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The goal of this trial is to learn if a resilience intervention can lead to improvements in lymphoma survivors' quality of life.
The Stress Management and Relaxation Response Resiliency Program for lymphoma survivors (SMART3RP-Lymphoma) was adapted by researchers at the MGH. This group program seeks to buffer stress and promote psychological resiliency and physical well-being through a variety of mind-body approaches, such as imagery, relaxation, and yoga, cognitive behavioral strategies, and positive psychology tools.
The main questions it aims to answer are:
To answer these questions, researchers will compare a resilience intervention tailored to the needs of lymphoma survivors (SMART3RP-Lymphoma) to a Health Education Program to see how they affect quality of life of lymphoma survivors.
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Health Education Program | Active Comparator | Participants will participate in 8 weekly sessions. Components include:
HEP is an active control condition for mind body programs and is structurally equivalent to SMART3RP |
|
| SMART3RP-Lymphoma | Experimental | Participants will participate in 8 weekly sessions. The intervention components include:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Health Education Program | Other | 8 weekly sessions that include education on the co-occurrence of mental and physical problems, goal setting for health behavior change, and self-monitoring. Each session includes basic didactic information, interactive application of the information, and open discussion of didactic material. |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of Life (QoL): Change in PROMIS-29 | To examine the effects of the SMART3RP-Lymphoma vs. a Health Education Program (HEP) in improving quality of life in early posttreatment lymphoma survivors. Quality of life will be measured using the PROMIS-29 which assesses physical, functional, emotional, and social quality of life. Each survey item is measured on a 1-5 scale. The unit of measurement is a score on a scale. | From enrollment to 6 month follow up |
| Measure | Description | Time Frame |
|---|---|---|
| Resilience: Change in Scores on the Current Experiences Scale (CES) | To compare the effects of the SMART3RP-Lymphoma vs. a Health Education Program (HEP) on resilience in posttreatment lymphoma survivors. Resilience will be measured by the Current Experiences Scale (CES). The CES is a 23-item measure that assesses the following domains of resilience on 0-5 scale: appreciation for life, adaptive perspectives, personal strength, spiritual connectedness, relating to others, and health behaviors. The unit of measurement is a score on a scale. |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between scores on measures of Resilience (CES) and Quality of Life (PROMIS-29) | The investigators will determine how resilience at 3 months correlates to quality-of-life improvements at 6 and 12 months. Resilience will be measured by the Current Experiences Scale (CES), which is a 23-item measure. The CES assesses 6 domains of resilience including appreciation for life, adaptive perspectives, personal strength, spiritual connectedness, relating to others, and health behaviors). Quality of life will be measured by the PROMIS-29 which is a 29-item measure. It assesses physical, functional, emotional, and social quality of life domains. The unit of measurement for both assessments are scores on a scale. |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mass General Hospital | Boston | Massachusetts | 02114 | United States |
de-identified information as required by the NIH
Information will be made available as required by the NIH in public repository and via clinicaltrials.gov
Researchers submitting formal requests as required and allowable by the NIH will be able to access supporting information.
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| ID | Term |
|---|---|
| D008223 | Lymphoma |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
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| SMART3RP-Lymphoma | Other | The SMART3RP-lymphoma is a group program that, through a variety of mind-body approaches, such as imagery, relaxation, and yoga, seeks to buffer stress and promote psychological resiliency and physical well-being. |
|
| Enrollment to 3 month follow up |
| 3, 6 and 12 months |
| D006425 | Hemic and Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |