This cross-sectional survey study will be conducted on a consecutive sample of physicians who treat patients with animal bites potentially requiring post-exposure anti-rabies prophylaxis. The sample will include emergency physicians, general practice or family physicians, and surgeons of both sexes, with varying degrees of experience and post-graduate clinical training.

All participants will consent to submit an anonymous Google Form-based questionnaire. The designed questionnaire will include introductory personal, academic, and work experience data about the physicians as gender, age, specialty, workplace, highest achieved medical-academic or training degree, and number of years of postgraduate clinical work experience. Candidates will be asked to reflect on their pre and postgraduate education/training quality and their confidence level in prescribing anti-rabies post-exposure prophylaxis treatment. (as a linear scale).

This study aims to investigate physicians' adherence to the Advisory Committee on Immunization.

Practices (ACIP) guidelines regarding Anti-rabies post-exposure prophylaxis in Egypt. This will be through a score given for the correct response to the case-based questionnaire. This questionnaire include 10 case-based scenarios where anti-rabies post-exposure prophylaxis may or may not be indicated as per ACIP guidelines. True response will be scored 1, wrong response will be scored 0 with maximum total score of 10. Higher score reflects better adherence to guidelines recommendations & vice versa.

This study attempts to evaluate the possible economic burden of this expected departure from the standard of care by examining doctors' compliance with appropriate prescription of anti-rabies post-exposure prophylaxis. Economic burden will be calculated by incorporating total odds ratio of inappropriate prescription of anti-rabies vaccine with or without human rabies immunoglobulin , cost of each dose of them to get a rough estimate of the expected cost rising from inappropriate prescription of theses drugs when they are not indicated.