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| Name | Class |
|---|---|
| Ondokuz Mayıs University | OTHER |
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This study aims to develop a non-invasive and contact-free diagnostic system that uses artificial intelligence (AI) to detect Chronic Obstructive Pulmonary Disease (COPD) by analyzing walking patterns.
Participants in this study will include individuals with a diagnosis of COPD and healthy volunteers. All participants will undergo a 6-minute walk test (6MWT), during which their movements will be recorded using video. In addition, they will complete a breathing test (spirometry) and a short questionnaire about symptoms.
The recorded videos will be analyzed using an AI model based on motion tracking software. This model will evaluate walking-related parameters such as step count, step length, walking time, and total walking distance. The goal is to determine whether walking patterns can be used to detect COPD with high accuracy, especially in situations where traditional lung function tests may not be available or feasible.
This study is observational and does not involve any experimental drug or treatment. The results may help to create new diagnostic tools that are easy to use, safe, and accessible for early detection of COPD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COPD Group | Participants with a confirmed diagnosis of Chronic Obstructive Pulmonary Disease (COPD) based on spirometry. |
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| Control Group | Healthy volunteers with no history of pulmonary disease and normal spirometry results. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gait Video Recording and Analysis | Other | Participants undergo a 6-minute walk test (6MWT) while being recorded on video. The footage is later analyzed using artificial intelligence algorithms to assess gait parameters. |
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic Accuracy of AI-Based Gait Analysis for Detection of COPD | Evaluation of the sensitivity, specificity, and overall accuracy of the artificial intelligence-based motion analysis system in identifying patients with COPD compared to spirometry (gold standard). | At time of initial assessment (Day 0) |
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Inclusion Criteria:
Exclusion Criteria:
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This study will include individuals between the ages of 40 and 80. The study population consists of two cohorts: patients previously diagnosed with Chronic Obstructive Pulmonary Disease (COPD) based on spirometry results, and healthy volunteers with no history of pulmonary disease. All participants must be physically able to complete a 6-minute walk test and willing to participate in video-based gait assessment.
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31369388 | Result | Altan G, Kutlu Y, Allahverdi N. Deep Learning on Computerized Analysis of Chronic Obstructive Pulmonary Disease. IEEE J Biomed Health Inform. 2019 Jul 26. doi: 10.1109/JBHI.2019.2931395. Online ahead of print. | |
| 36858443 | Result | Agusti A, Celli BR, Criner GJ, Halpin D, Anzueto A, Barnes P, Bourbeau J, Han MK, Martinez FJ, Montes de Oca M, Mortimer K, Papi A, Pavord I, Roche N, Salvi S, Sin DD, Singh D, Stockley R, Lopez Varela MV, Wedzicha JA, Vogelmeier CF. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Eur Respir J. 2023 Apr 1;61(4):2300239. doi: 10.1183/13993003.00239-2023. Print 2023 Apr. |
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Individual participant data (IPD) that underlie the results reported in this study will be shared with qualified researchers upon reasonable request. Data will be de-identified to protect participant confidentiality and shared for academic research purposes only, in accordance with institutional ethics approval and data protection policies.
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |