Brazilian Registry of Menopausal Health

Population-based Cross-sectional Observational Study for a Brazilian Registry of Menopausal Women and Associated Factors Related to Clinical Profile, Socioeconomic Aspects, Social Disparities, Access to Healthcare, Quality of Life, and Knowledge About Menopause

The Brazilian Registry of Menopausal Health is a national study aimed to better understand the health and quality of life of participants aged 35 to 65 who are in the menopausal transition or postmenopausal phase, including cisgender women and transgender men.

The study's hypothesis is that significant regional and socioeconomic disparities influence individuals' health, knowledge, and perception of menopause.

The Brazilian Registry of Menopausal Health, called EMBRACE STUDY (Endrocrine Mapping in the Broad Range Of Aging and Climateric Experiences), is an observational, cross-sectional, population-based study conducted with the objective of characterizing the epidemiological aspects of the Brazilian population during the menopausal transition and postmenopause, as well as the factors associated with clinical profiles and symptomatology, socioeconomic conditions, social inequalities, access to healthcare services, quality of life, and knowledge about menopause.

The study will include cisgender women and transgender men who have not undergone surgical or hormonal gender reassignment of secondary sexual characteristics, aged between 35 and 65 years, who seek outpatient care in public or private healthcare services.

A total of 1,592 participants will be enrolled, with 617, 509, and 466 participants in the respective age groups of 35-44, 45-54, and 55-65 years, proportionally stratified across the 27 state capitals of Brazil. These age groups will be used solely for the purpose of sample stratification.

Data about transgender men will be collected for exploratory purposes.

Inclusion Criteria:

1. Women aged between 35 and 65 years attending medical consultation at public and private outpatient health services;
2. Ability to confirm voluntary participation and sign the Informed Consent Form

Exclusion Criteria:

1. Inability to respond to the interview for any reason
2. Suspected or confirmed pregnancy
3. Lactation
4. Uncontrolled diabetes
5. Uncontrolled arterial hypertension
6. Uncontrolled thyroid disorders
7. Grade 3 obesity, defined by a BMI equal to or greater than 40.0 kg/m²
8. Diagnosis of psychiatric disorders that may compromise participation in the interview
9. Previous hysterectomy
10. Previous oophorectomy
11. Current use of illicit drugs