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| Name | Class |
|---|---|
| First Affiliated Hospital, Sun Yat-Sen University | OTHER |
| Liaoning Health Industry Group Fushun Mining General Hospital | UNKNOWN |
| Liaoning Health Industry Group Benxi Steel General Hospital | UNKNOWN |
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The main objective of this study is to evaluate the efficacy and safety of Metformin Hydrochloride and Empagliflozin Tablets in the treatment of type 2 diabetes in real-world clinical settings. A total of 2,600 type 2 diabetes patients were included in the study. The study observed the clinical glycemic control rate and adverse events over a period of at least 6 months from the prescription date to the end of continuous clinical follow-up.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Metformin Hydrochloride and Empagliflozin tables (Fixed-Dose Combination) | Drug | First-time treatment with Metformin Hydrochloride and Empagliflozin Tablets (metformin 500mg and empagliflozin 5mg per table) for at least 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| 6-month clinical glycemic control rate | 6-month clinical glycemic control rate (clinical control defined as HbA1c < 7.0%) | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in HbA1c from baseline | Change in HbA1c from baseline at 12 months | 12 months |
| Change of β cell function | Change of β cell function at 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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Outpatient and inpatient patients
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Endocrinology Department, The First Affiliated Hospital of Sun Yat-sen University | Guangzhou | Guangdong | China |
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| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D008687 | Metformin |
| ID | Term |
|---|---|
| D001645 | Biguanides |
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
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| Changsha Fourth Hospital | OTHER_GOV |
| Second Hospital of Shanxi Medical University | OTHER |
| The First People's Hospital of Kunshan | OTHER |
| Suzhou Ninth People's Hospital | UNKNOWN |
| the First Affiliated Hospital of Anhui University of Science and Technology | UNKNOWN |
| Mingguang People's Hospital | UNKNOWN |
| the People's Hospital Longhua Shenzhen | UNKNOWN |
| Affiliated Hospital of North Sichuan Medical College | OTHER |
| Yiyang County People's Hospital | UNKNOWN |
| THE SECOND PEOPLE'S HOSPITAL, WUHU | UNKNOWN |
| The First People's Hospital of Zhangjiagang | UNKNOWN |
| Yixing People's Hospital | OTHER |
| Shijiazhuang People's Hospital | OTHER |
| The First People's Hospital of Guiyang | OTHER |
| Lanzhou University Second Hospital | OTHER |
| Tiefa Coal Industry Group General Hospital | UNKNOWN |
| Shenzhen Hospital of Southern Medical University | OTHER |
| The Second Hospital of Shijiazhuang | UNKNOWN |
| The Affiliated People's Hospital of Ningbo University | OTHER_GOV |
| Dongyang People's Hospital | OTHER |
| Xiangyang Central Hospital | OTHER |
| Li Hui Li Hospital | UNKNOWN |
| Nanning Second People's Hospital | OTHER |
| Hunan Provincial People's Hospital Ma Wang Dui Branch | UNKNOWN |
| Second Affiliated Hospital of Bengbu Medical College | OTHER |
| Ruyang County People's Hospital | UNKNOWN |
| Kaifeng People's Hospital | UNKNOWN |
| Dingzhou People's Hospital | UNKNOWN |
| The Second People's Hospital of Changshu | UNKNOWN |
| The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine | OTHER |
| Dengzhou People's Hospital | UNKNOWN |
| Taizhou First People's Hospital | OTHER |
| Red Cross Hospital, Hangzhou, China | OTHER |
| First People's Hospital of Hangzhou | OTHER |
| China Resources Wugang General Hospital | UNKNOWN |
| Yiwu Central Hospital | OTHER |
| The First People's Hospital of Jiashan County | UNKNOWN |
| The First People's Hospital of Tongxiang City | UNKNOWN |
| Shaoxing Central Hospital | OTHER |
| The First People's Hospital of Jiande City | UNKNOWN |
| Beilun District People's Hospital | UNKNOWN |
| Huantai County People's Hospital | UNKNOWN |
| Fifth Affiliated Hospital of Guangzhou Medical University | OTHER |
| Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University | OTHER |
| Shaanxi Hospital of Traditional Chinese Medicine | OTHER |
| Zhangjiagang Traditional Chinese Medicine Hospital | UNKNOWN |
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| 12 months |
| Change of insulin sensitivity | Change of insulin sensitivity indicators at the end of study | 12 months |
| Change of lipid profiles | Change of cholesterol, Triglyceride, high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) at the end of study | 12 months |
| Change of body weight | Change of body weight at the end of study | 12 months |
| Changes in echocardiographic indicators in type 2 diabetes patients with cardiovascular disease | Changes in echocardiographic indicators in type 2 diabetes patients with cardiovascular disease at the end of study | 12 months |
| Change of blood pressure | Change of blood pressure at the end of study | 12 months |
| Change of Quality of life assessment (EQ-5D) | Change of Quality of life assessment (EQ-5D) at the end of study | 12 months |
| Incidence of adverse events | incidence of adverse events at the end of study | 12 months |
| D004700 | Endocrine System Diseases |