Pain, anxiety, anxiety and changes in vital signs are observed in patients during needle insertion into the port catheter.Patients and their relatives should be informed by nurses to eliminate these problems and to provide more comfortable infusion to patients.However, studies on the care process for the symptoms that occur before port catheter infusion are limited in the literature.The thesis study planned for this purpose will be carried out to determine the effect of the training given before port catheter infusion on infusion-related symptoms.The research will be conducted as pretest-posttest, randomised controlled.Oncology-Hematology Services and Chemotherapy Unit of Karadeniz Technical University Farabi Hospital.The sample of the study will be determined by simple randomisation method and 64 patient will be included in the study.The data of the study will be collected by Patient Descriptive Information Form, Visual Analogue Scale and State and Trait Anxiety Scale, Vital Signs Follow-up Chart.

Inclusion Criteria:

• Having a port catheter
• The patient has no previous experience with a port catheter,
• The patient will receive an infusion from a port catheter for the first time,
• The patient's age range is between 18-70,
• The patient is literate,
• Volunteering to participate in the study,
• The patient will receive training from the training material for the first time.

Exclusion Criteria:

• Those with communication, hearing and vision problems,
• Those with any psychiatric disorder,
• Those who used any analgesic medication at least 8 hours before