Dobutamine During Major Abdominal Surgery

Dobutamine During Major Abdominal Surgery: A Randomized Pilot Trial (PUSH-1)

The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.

Inclusion Criteria:

• Consenting patients ≥18 years scheduled for elective major abdominal surgery under general anesthesia (expected surgery duration ≥ 120 minutes)
• Planned continuous intraarterial blood pressure monitoring using an arterial catheter for clinical indications not related to the trial

Exclusion Criteria:

• Emergency surgery
• Liver or kidney transplantation surgery
• Status of post transplantation of kidney, liver, heart, or lung
• Pregnancy
• Heart rhythms other than sinus rhythm