Indocyanine Green Fluorescence Angiography (ICG-FA) in Revisional Bariatric Surgery

Prospective Single-center Diagnostic Parallel-group Study to Determine the Minimal Dose of Indocyanine Green to Observe Vascular Perfussion in Revisional Bariatric Surgery.

This study will compare different doses of a green fluorescent product that is administered during weight loss surgery in order to observe where blood vessels are located. There is uncertainty around the optimal dose of this product for patients with obesity, so this study will aim to study if the dose in the minimal range recommended by international guidelines is sufficient for most patients or if higher doses are needed with increasing body mass index.

Inclusion Criteria:

• Diagnosis of obesity with a BMI ≥ 30 kg/m²
• Scheduled for revisional bariatric surgery

Exclusion Criteria:

• Allergy to iodides.
• Anticoagulation with products containing sodium bisulfite (due to the risk of ICG-FA inactivation).
• Use of radioactive iodine studies within the past 7 days.
• Pregnant, breastfeeding, or planning to become pregnant within the next year (due to unknown teratogenic or fertility effects of ICG-FA).
• History of liver disease or laboratory findings suggestive of moderate to severe hepatic disease: total bilirubin >1.5 times the upper limit of normal (ULN), or any elevation of aspartate aminotransferase (AST) above ULN.
• Participants who withdraw their consent to participate in the study (elimination criterion).