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Stroke-related gait impairments, such as poor limb coordination, imbalance, and reduced push-off strength, are often addressed using robotic systems or electrical stimulation, which can be costly, invasive, or insufficient for long-term recovery. Current devices often assist movement but fail to promote functional motor learning. Research supports rehabilitation strategies that amplify gait errors to drive neuroplasticity and adaptation. The LegExoNET (Exoskeletal Network for Elastic Torque) is a novel, passive wearable exoskeleton designed to address this need by enabling both assistive and therapeutic gait training. It stores and releases elastic energy to aid movement while allowing natural joint motion. The system aims to support individuals post-stroke transitioning to independent rehabilitation by offering a lightweight, affordable, and adaptive solution. Initial testing will focus on healthy individuals to assess safety and feasibility before expanding to stroke populations. The LegExoNET has the potential to enhance gait recovery and reduce therapist burden through error augmentation and personalized support, both in clinical and at-home settings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Experimental | Participants will receive Sham → Assist → Resist in a crossover design. |
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| Group 2 | Experimental | Participants will receive Sham → Resist → Assist in a crossover design |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Assist | Other | The device will provide assistive torques to support either ankle, knee, and/or hip movements. |
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| Measure | Description | Time Frame |
|---|---|---|
| Electromyography (EMG) amplitude during walking under each intervention condition | Muscle activation (specifically voltage amplitude) using wearable surface EMG of the gastrocnemius, lateral gastrocnemius, tibialis anterior, soleus, biceps femoris, rectus femoris, and gluteus maximus. | Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham) |
| Measure | Description | Time Frame |
|---|---|---|
| 6 Minute Walk Test |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marc Camardo | Contact | 224-422-7182 | mcamardo@sralab.org |
| Name | Affiliation | Role |
|---|---|---|
| James L Patton, PhD | Shirley Ryan AbilityLab | Principal Investigator |
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| ID | Term |
|---|---|
| D007316 | Insemination, Artificial, Heterologous |
| ID | Term |
|---|---|
| D007315 | Insemination, Artificial |
| D027724 | Reproductive Techniques, Assisted |
| D012099 | Reproductive Techniques |
| D013812 | Therapeutics |
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All participants will receive either intervention, but the order in which they receive it will be randomized.
| Resist | Other | The device will apply resistive torques to exaggerate gait asymmetries, facilitating error augmentation. |
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| Slack | Other | The device will be worn but will not generate any torque. |
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| Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham) |
| 10 Meter Walk Test | The individual is instructed to walk a set distance (6 meters, 10 meters, etc). Time is measured while the individual walks the set distance (often the individual is given space to accelerate to his/her preferred walking speed (this distance is not included when determining speed). The distance covered is divided by the time it took the individual to walk that distance. | Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham) |
| Gait Symmetry | Collect gait symmetry and other gait parameters such as stride length, using Kinect v2, GaitRite, and OpenCap. Kinect v2 tracks 3D joint kinematics to assess symmetry (left-right differences), stride length (foot displacement), and parameters like step time and velocity. GaitRite's pressure-sensitive walkway measures precise stride length, symmetry (step length/time differences), and parameters such as cadence and stance time. OpenCap, with multiple cameras and cloud processing, captures 3D kinematics to calculate symmetry, stride length, joint angles, and the Gait Deviation Index (GDI). Data will be synchronized, systems calibrated, and participants will walk naturally for analysis using dedicated software and scripts, ensuring comprehensive gait evaluation. | Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham) |
| D008919 | Investigative Techniques |
| D007314 | Insemination |
| D012098 | Reproduction |
| D055703 | Reproductive Physiological Phenomena |
| D012101 | Reproductive and Urinary Physiological Phenomena |