The objectives of this study are to determine if the 'Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress' (TEAM-LEADS) intervention is feasible and acceptable to adolescents and young adults with lupus and dermatomyositis and whether it can help reduce stress and promote cardiovascular health behaviors in these individuals.

Patients with juvenile systemic lupus erythematosus (JSLE) and juvenile dermatomyositis (JDM) are at higher risk of cardiovascular disease, with premature mortality. Adolescents and young adults with JSLE/JDM experience high rates of psychological stress which is associated with worse cardiovascular health (CVH) behaviors, including inadequate physical activity, diet quality, and sleep. However, evidence-based behavioral interventions for stress reduction remain inaccessible for many adolescents and young adults with JSLE/JDM. There is a critical need for stress reduction interventions that are effective, accessible, and tailored to JSLE/JDM-specific experiences. 'Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress', or TEAM-LEADS, is an online stress reduction and CVH behavior promotion intervention for adolescents and young adults with JSLE/JDM. TEAM-LEADS will be evaluated in a Phase I open-label, single-arm successive cohort pilot trial in adolescents and young adults with JSLE and JDM. Participants will complete the online intervention and assessments at baseline, post-intervention, and follow-up. The study will evaluate feasibility, acceptability, adherence, and preliminary efficacy for stress reduction and CVH behavior promotion.

Inclusion Criteria:

• Diagnosis of juvenile-onset systemic lupus erythematosus (JSLE) or dermatomyositis (JDM)
• Age 13-22 years old at time of enrollment

Exclusion Criteria:

• Inability to complete surveys/interviews reliably
• Lack of access to internet-enabled device;
• Non-JSLE/JDM diagnosis
• History of myocardial infarction or cerebrovascular accident
• Evidence of severe emotional distress defined as any of the following at time of screening: a) Patient Health Questionnaire for Adolescents (PHQ9A) score ≥ 15 indicating severe depression; b) PHQ9A suicidality item score > 0 indicating presence of any suicidal ideation; c) any other evidence noted of severe emotional distress per PI's judgment.

Study protocols, data collection instruments, data dictionaries, and statistical analysis plans will be deposited in Vivli repository via Duke University's institutional license.

Data will be made available at time of publication or the end of the performance period (whichever comes first). At a minimum, Vivli will make data available for researchers for 10 years, unless they are contractually unable to do so.

Vivli provide metadata, persistent identifiers (e.g. NCT ID), study search functions, and long-term access. Vivli repository is available to Duke investigators via institutional license and datasets are available via standardized process in which requestors search Vivli platform for the study, request the IPD data package (with requests reviewed per contributor's publicly stated requirements), and then access data in Vivli's secure environment (or download with permission).