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Pregnant women who established prenatal examination cards in the prenatal outpatient department of our hospital from January 2025 to September 2025 were selected. According to the inclusion criteria, 200 high-risk pregnant women with gestational diabetes mellitus (GDM) were selected. 100 people in the control group received conventional nursing intervention measures, and 100 people in the intervention group adopted the family-centered wechat platform interactive management nursing model. The observation period was from the start of prenatal examination to follow-up until delivery. The blood glucose conditions, glycated hemoglobin (HbA1c) levels, incidence of GDM, and weight gain during pregnancy of the two groups of pregnant women were observed. The pregnancy outcomes included: Gestational age at delivery, gestational complications (gestational hypertension, diabetic ketosis, preterm birth, post-term pregnancy, urogenital tract infection), polyhydramnios, mode of delivery (induced labor, shoulder dystocia, cesarean section), premature rupture of membranes, postpartum complications (postpartum hemorrhage, puerperal infection), etc. Perinatal outcomes: including fetal growth restriction, macrosomia, preterm birth, stillbirth, fetal malformations, fetal distress, neonatal respiratory distress syndrome, neonatal hypoglycemia, etc. We applied FCC to pregnant women at high risk of gestational diabetes mellitus (GDM) and advanced the intervention window to the beginning of prenatal examination (8-10 weeks of pregnancy). This may be able to improve weight gain and blood glucose levels during pregnancy in high-risk pregnant women, reduce the incidence of GDM, improve the final maternal and infant outcomes, and provide a certain theoretical basis for prenatal nursing intervention in pregnant women at high risk of GDM in the future.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | Experimental |
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| Intervention group | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Control group:The interactive management nursing model on the wechat platform | Behavioral | The intervention subjects of the control group: targeted at the pregnant and postpartum women themselves. Specifically, conduct routine outpatient prenatal examinations and health education for pregnant women. Regularly receive health education and pregnancy guidance intervention provided by the wechat platform. It includes: ① Setting specific wechat ringtones, 60-second voice messages and picture reminders every day; ② Basic knowledge education every Monday ③ Dietary guidance is provided every Tuesday. ④ Exercise guidance every Wednesday ⑤ Guidance on blood glucose monitoring every Thursday; Weight guidance is provided every Friday. |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of gestational diabetes | The number of cases of GDM/the total number of observed cases | 24 weeks of gestation |
| Measure | Description | Time Frame |
|---|---|---|
| Blood sugar status of pregnant women | The occurrence of abnormal OGTT (OGTT examination was performed at 24 weeks, and fasting, 1-hour, and 2-hour blood glucose were measured), and the level of glycated hemoglobin (HbA1c) | 24 weeks of gestation |
| The weight gain of pregnant women during pregnancy |
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Inclusion Criteria:
Gestational age <10 weeks Singleton pregnancy confirmed by first-trimester ultrasound
Primary caregiver availability: At least one primary caregiver (spouse or parent) who:
Metabolic risk factors meeting ≥1 criterion:
Preterm delivery (<37 weeks) Stillbirth or fetal demise Congenital malformations Neonatal death or unexplained neonatal death
Exclusion Criteria:
Pre-existing medical conditions:
Prohibited medication use during pregnancy including:
Activity-limiting comorbidities:
a) Severe medical complications contraindicating physical activity (e.g., unstable angina, advanced respiratory failure)
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nantong First People's Hospital | Nantong | Jiangsu | 226001 | China |
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| Intervention group:Family-centered early care intervention | Behavioral | The intervention subjects of the intervention group were parturients and their primary caregivers (spouses and parents). The specific measures are as follows:
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The pre-pregnancy BMI was lower than the normal value, and the weight gain during pregnancy was 12.5-18.0kg. Those with a normal BMI before pregnancy gained 11.5 to 16.0kg during pregnancy. Those with an excessive BMI before pregnancy gained 7.0 to 11.5 kilograms during pregnancy. Obese people before pregnancy gain 5.0 to 9.0 kilograms during pregnancy. Weight gain during pregnancy is classified into three levels: insufficient weight gain, appropriate weight gain, and excessive weight gain. If the weight gain during pregnancy is less than the corresponding pre-pregnancy BMI weight gain range, it is considered insufficient weight gain; if it is greater than the corresponding weight gain range, it is considered excessive weight gain. |
| From randomization to pregnancy termination (maximum assessment time: 42 weeks of gestation) |
| Gestational weeks at delivery | Gestational age at delivery (based on the gestational age confirmed by the last menstrual period or early ultrasound) | From pregnancy confirmation to delivery (range: ≥20 weeks to ≤42 weeks) |
| Complications during pregnancy | Clinical diagnosis of gestational hypertension, preeclampsia, diabetic ketoacidosis, preterm birth (<37 weeks), post-term pregnancy (≥42 weeks), and urogenital tract infections | From enrollment to delivery |
| Polyhydramnios | Ultrasound diagnosis: Amniotic fluid index (AFI) >24 cm or maximum vertical amniotic fluid depth (MVP) >8 cm | Middle and late stages of pregnancy (such as being evaluated every 4 weeks after 20 weeks of pregnancy until delivery) |
| Postpartum complications | The incidence of postpartum hemorrhage (blood loss ≥500ml) and puerperal infection (body temperature ≥38℃+ laboratory confirmation) | From delivery to discharge (or within 42 days after delivery) |
| Mode of delivery | The incidence rates of induced labor, shoulder dystocia and cesarean section | Records during childbirth |
| Premature rupture of membranes | Clinical diagnosis of natural rupture of membranes before labor | Pregnancy ≥37 weeks until before delivery |
| The length and cost of hospital stay after delivery | Length of hospital stay (days) and total cost | From delivery to discharge |
| Fetal growth restriction | Ultrasound assessment of fetal weight < the 10th percentile at the same gestational week | The assessment should be conducted every 4 weeks after 20 weeks of pregnancy until delivery |
| Macrosomia | Birth weight ≥4000g | Records during childbirth |
| Premature birth | The gestational age at delivery is less than 37 weeks | From enrollment to delivery |
| Stillbirth | Fetal death occurs after ≥20 weeks of pregnancy | From enrollment to delivery |
| Fetal malformation | Congenital malformations confirmed by ultrasound or clinically after birth | During the second trimester of pregnancy (18-24 weeks) and within 24 hours after birth |
| Fetal distress | Abnormal fetal heart rate monitoring (such as repeated late deceleration) or amniotic fluid fecal contamination | Records during childbirth |
| Neonatal respiratory distress syndrome | Clinical diagnosis (aerobic therapy or ventilator support + chest X-ray confirmation) | Within 7 days after birth |
| Neonatal hypoglycemia | Blood glucose <2.6mmol/L (at least two tests are required for confirmation) | Within 24 hours after birth |
| The rate of newborns admitted to the NICU | Indications and days of transfer to the Neonatal Intensive Care Unit (NICU) | From birth to discharge (or within 28 days after birth) |
| ID | Term |
|---|---|
| D016640 | Diabetes, Gestational |
| ID | Term |
|---|---|
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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