Nitazoxanide in Patients With Ulcerative Colitis

Clinical Study to Evaluate Safety and Efficacy of Nitazoxanide in Patients With Ulcerative Colitis.

Ulcerative colitis (UC) is a chronic inflammatory bowel Disease (IBD) that primarily affects the rectum and colon. The severity and persistence of mucosal inflammation are associated with morbidity and mortality.

Inclusion Criteria:

• Age ≥ 18 years
• Both male and female will be included
• Mild and moderate UC patients are already diagnosed and confirmed by endoscope and histopathology.

Exclusion Criteria:

• Breast feeding or pregnancy.
• Colorectal cancer patients.
• Patients with severe UC.
• Patients taking rectal or systemic steroids.
• Patients taking immunosuppressives or biological therapies.
• Addiction to alcohol and / or drugs.
• Known allergy to the studied medications.