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Oral clinical descriptions related to adverse events in patients treated with those elective multi-targeted receptor tyrosine kinase inhibitors and a recombinant humanised monoclonal antibody
Electronical medical and dental records, high-resolution digital photograph were reviewed. Demographic data, medical background, clinical and laboratory information were recorded for each individual case.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| angiogenesis inhibitors | Oral clinical manifestation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clinical evaluation | Other | treatment methods, associated symptoms, evolution and clinical presentation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Benign migratory glossitis | erythematous erosions, with loss of filiform papillae, surrounded by white circinate rims on the dorsal tongue | From enrollment to the end of study at 7 years |
| Measure | Description | Time Frame |
|---|---|---|
| Adverse events | Dysgeusia , dermatologic toxicities such as skin erythemas and vesicles on the palms of the hands and burning sensation | From enrollment to the end of study at 7 years |
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Inclusion Criteria:
Exclusion Criteria:
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Hospital -Instituto do Cancer do Estado de Sao Paulo-ICESP
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| Name | Affiliation | Role |
|---|---|---|
| Mauricio Neves Gomes, PhD | Instituto do Cancer do Estado de São Paulo | Principal Investigator |
| Wagner Gomes da Silva, PhD | Instituto do Cancer do Estado de São Paulo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto do Cancer do Estado de São Paulo | São Paulo | São Paulo | 01246-000 | Brazil |
undecided
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D005929 | Glossitis, Benign Migratory |
| ID | Term |
|---|---|
| D005928 | Glossitis |
| D014060 | Tongue Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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