Hand Dysfunction in Coronary Diagnosis and Intervention Via Distal Radial Access

COmparison of the HaNd DysFunction in Coronary Diagnosis and INtervention Via Distal vs Conventional Radial AccEss: Randomized Controlled Trial (CONFINE)

Randomized controlled trial for comparison of the hand dysfunction in coronary diagnosis and intervention via distal vs conventional radial access

Coronary diagnosis and intervention via distal radial access has gradually become an alternative access to the conventional radial access because of its advantages of reducing radial artery occlusion (RAO), shortening compression time, and decreasing patient discomfort. However, as awareness of distal radial access has increased, some patients have been found to have symptoms such as abnormal hand sensation and inflexibility after the procedure.

The primary objective is to assess hand function after coronary diagnosis and intervention via distal vs conventional radial access at 24 hours and 1 month.

Hand sensory and motor dysfunction will be assessed by:

• Consultation and physical examination
• Hand grip test
• Hand pinch test (lateral pinch)
• Monofilament sensory test
• Quick DASH questionnaire
• High-frequent ultrasound The other endpoints include the success rate of puncture, the success rate of single-attempt puncture, time of puncture, procedural duration, duration of hemostasis, vascular complication, etc.

Inclusion Criteria

• Indications for coronary diagnosis and intervention
• Distal and conventional radial artery pulsation are palpable
• Patient should be able to comply with the protocol

Exclusion Criteria

• Age < 18 years or ≥ 90 years
• Height ≥ 185 cm
• Acute STEMI
• Haemodynamic instability
• Contraindications to puncture at the puncture site (such as infection, scarring or indwelling needles)
• Enrollment in another study that competes or interferes with this study