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The aim of this study is to describe the results of cardiac radiofrequency ablation under general anesthesia.
to evaluate mechanical ventilation methods in pediatric patients. The main questions it aims to answer are
Radiofrequency ablation (RF) is an effective method for the threatment of cardiac arrhythmias in pediatric patients. General anaesthesia and mechanical ventilation is the most common anesthesia management for pediatric arrhythmia patients. During the prosedure, thoracic excursion results in displacement of the catheter and disrupts the catheter stability which is crucial for quality of contact force (CF), sufficient ablation and safety. To minimize the thoracic excursion, high frequency low tidal volume ventilation and apnea ventilation may be needed during radiofrequency ablation. According to investigators knowledge there are studies about ventilatory strategies in adult patients who underwent cardiac radiofrequency ablation. However, there are no studies corcerning pediatric patients. In this study investigators aimed to investigate best ventilatory strategy for minimize thoracic excursion in pediatric patients with general anaesthesia. In this study investigators are going to observe 3 different ventilation strategies on radiofrequency ablation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1) Lung protective mechanical ventilation | Mechanical ventilation with 7-9 ml tidal volume during RF | ||
| 2) Low tidal volume high frequency ventilation | Mechanical ventilation with 4 ml tidal volume with high frequency during RF | ||
| 3) Apnea ventilation | Apne ventilastion during RF |
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| Measure | Description | Time Frame |
|---|---|---|
| Contact force | continuously measured through the catheter | intraprosedural |
| Measure | Description | Time Frame |
|---|---|---|
| Lession count | number of successful lesions | intraprosedural |
| Time | RF time | intraprosedural |
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Inclusion Criteria:
Exclusion Criteria:
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During the 3-month period, cardiac paediatric patients undergoing radiofrequency ablation under general anaesthesia in the catheterisation laboratory will be analysed
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| Name | Affiliation | Role |
|---|---|---|
| Gözde Gürsoy Çirkinoğlu, MD | Izmir City Hospital, Anesthesiology and Reanimation Department | Principal Investigator |
| Halide Hande Sahinkaya, MD | Izmir City Hospital, Anesthesiology and Reanimation Department | Study Chair |
| Zeki Tuncel Tekgül, Prof. Dr. | University of Health Sciences, Izmir City Hospital, Anesthesiology and Reanimation Department | Study Chair |
| Cem Karadeniz, Prof. Dr | Izmir Katip Celebi University Medical Faculty, Pediatric Cardiology Department | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| İzmir City Hospital | Izmir | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35333095 | Result | Osorio J, Varley A, Kreidieh O, Godfrey B, Schrappe G, Rajendra A, Silverstein J, Romero J, Rodriguez D, Morales G, Zei P. High-Frequency, Low-Tidal-Volume Mechanical Ventilation Safely Improves Catheter Stability and Procedural Efficiency During Radiofrequency Ablation of Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2022 Apr;15(4):e010722. doi: 10.1161/CIRCEP.121.010722. Epub 2022 Mar 25. No abstract available. | |
| 30573114 |
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| Result |
| Sivasambu B, Hakim JB, Barodka V, Chrispin J, Berger RD, Ashikaga H, Ciuffo L, Tao S, Calkins H, Marine JE, Trayanova N, Spragg DD. Initiation of a High-Frequency Jet Ventilation Strategy for Catheter Ablation for Atrial Fibrillation: Safety and Outcomes Data. JACC Clin Electrophysiol. 2018 Dec;4(12):1519-1525. doi: 10.1016/j.jacep.2018.08.016. Epub 2018 Nov 1. |
| 34137629 | Result | Janson CM, Shah MJ, Kennedy KF, Iyer VR, Sweeten TL, Glatz AC, Steven JM, O'Byrne ML. Comparison of Outcomes of Pediatric Catheter Ablation by Anesthesia Strategy: A Report From the NCDR IMPACT Registry. Circ Arrhythm Electrophysiol. 2021 Jul;14(7):e009849. doi: 10.1161/CIRCEP.121.009849. Epub 2021 Jun 17. |