This study aims to evaluate the impact of a structured education program delivered under midwife guidance on menopause-specific quality of life among women aged 45-55 undergoing natural menopause, and to assess the sustainability of its effects over time.

This randomized controlled longitudinal study was conducted with 101 women aged 45-55 experiencing natural menopause (intervention: 51, control: 50). The intervention group received a structured menopause education program developed based on literature and expert review. Data were collected using a Personal Information Form and the Menopause-Specific Quality of Life Questionnaire (MENQOL) at three time points: baseline (T1), after education (T2), and six months later (T3). The intervention consisted of four weekly face-to-face sessions delivered by a midwife. The education content included information on menopausal changes, symptoms, and coping strategies. The control group received no intervention during the study but received educational material after final data collection. Data were analyzed using SPSS 20.0 with p<0.05 considered statistically significant.

Inclusion Criteria:

• • Women aged 45-55

  • Experiencing natural (non-surgical) menopause
  • Literate and able to complete questionnaires
  • No neurological or cognitive impairments
  • Willing to participate and attend sessions
  • Has access to phone/internet

Exclusion Criteria:

• Surgical menopause
• Hormonal disorders causing amenorrhea
• Current use of hormonal therapy or antidepressants
• Diagnosed psychiatric conditions

Removal Criteria (if applicable):

• Did not attend at least 80% of sessions
• Lost to follow-up at 6 months
• Developed a new health issue affecting menopause
• Participated in other menopause interventions
• Incomplete or inconsistent questionnaire

There is no plan to share individual participant data (IPD).

The study was not blinded; both participants and investigators were aware of group assignments.