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Postoperative pain after laparoscopic cholecystectomy can be considerable. Regional techniques such as erector spinae plane (ESP) block or transversus abdominis plane (TAP) block may be suitable for patients at increased risk of postoperative pain. The deep rectus sheath block is a novel block which is a modified version of the conventional rectus sheath block. It was reported in a few case reports that, it may be used for postoperative analgesia in patients undergoing laparoscopic cholecystectomy. The aim of this study is to investigate the postoperative analgesic efficacy of deep rectus sheath block in patients undergoing laparoscopic cholecystectomy.
Patients scheduled for elective laparoscopic gastrectomy will be separated into 2 groups: Control Group and Deep Rectus Sheath Block Group. Patients in Control Group will be received patient controlled analgesia with morphine for postoperative analgesia. Patients in Deep Rectus Sheath Block Group will be performed Deep Rectus Sheath Block at the end of the surgery, along with patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, numerical rating scale scores, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | Active Comparator | The patients in Control Group will be received patient controlled analgesia with morphine for postoperative analgesia |
|
| Deep rectus sheath block group | Active Comparator | The patients in deep rectus sheath block group will be received deep rectus sheath block and patient controlled analgesia with morphine for postoperative analgesia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intravenous morphine patient control analgesia | Other | 24-hour morphine consumption will be recorded |
|
| Measure | Description | Time Frame |
|---|---|---|
| Morphine consumption | The amount of morphine required by the patient and given by the device will be recorded for the first 24 hours. | Postoperative 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative numerical rating scale scores | Postoperative pain will be assessed using a numerical rating scale (NRS) (from 0 = no pain to 10 = maximum possible pain) for the first 24 hours. | Postoperative 24 hours |
| Rescue analgesic drug requirement |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Taylan Sahin, M.D. | Contact | +902129794000 | taylansah@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Taylan Sahin, M.D. | Istinye University | Principal Investigator |
| Ali Sait Kavakli, M.D. | Istinye University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istinye University Hospital | Recruiting | Istanbul | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42303918 | Derived | Kavakli AS, Bozkurt MA, Diri M, Sahin T, Koc U, Ipek ZSK, Cekem A. Preperitoneal analgesia under direct visualization: laparoscopic-guided deep rectus sheath block improves postoperative pain control after laparoscopic cholecystectomy: a randomized controlled trial. Surg Endosc. 2026 Jun 16. doi: 10.1007/s00464-026-12973-5. Online ahead of print. |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| Intravenous patient control analgesia | Other | 24-hour morphine consumption will be recorded |
|
| Deep rectus sheath block | Other | Deep rectus sheath block will be administered at the end of the surgery. |
|
The amount of rescue analgesic in mg required by the patient will be recorded for the first 24 hours.
| Postoperative 24 hours |
| Incidence of postoperative nausea and vomiting | Number of patients developing postoperative nausea and vomiting will be recorded for the first 24 hours | Postoperative 24 hours |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |