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| Name | Class |
|---|---|
| Xi'an Jiaotong University | OTHER |
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With the deepening of societal aging, degenerative spinal diseases have become increasingly prevalent in China and are one of the leading causes of disability among middle-aged and elderly populations. Current musculoskeletal assessment methods primarily focus on imaging rather than functional evaluation, and emphasize static over dynamic analysis, failing to capture the daily functional state of the musculoskeletal system. This limitation hinders a deeper understanding of functional patterns and their role in the progression of degenerative spinal diseases. Therefore, there is an urgent need to develop precise and dynamic functional assessment methods that overcome the constraints of time and space in measurement. This project adopts a dynamic perspective of the musculoskeletal system, developing a wearable monitoring approach based on flexible sensors to assess limb and spinal motion. The method will be validated against traditional imaging techniques such as X-ray and ultrasound, laying the foundation for investigating the pathogenesis of degenerative spinal diseases. This research aligns with China's strategic initiatives and practical needs in addressing the challenges of an aging population.
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| Measure | Description | Time Frame |
|---|---|---|
| Motor and Stabilizing Function of the Spine | The assessment of spinal stability at the baseline involves evaluating flexion-extension mobility in the sagittal plane, lateral bending capability in the coronal plane, and detecting relative displacement between vertebral segments during three-dimensional motion. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Limb Motor Function | Assessment of Limb Muscle Strength Function Using Dynamometer Grip Strength Tests and Hand Function Scoring at the baseline. | Baseline |
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We are recruiting patients with spinal diseases, including cervical spondylosis with hand dysfunction, kyphosis/spinal imbalance, scoliosis (Cobb angle 20°-50°), and lumbar spondylolisthesis (>3mm dynamic slip).
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Weishi Li | Contact | +8615701206146 | hangengyu@pku.edu.cn |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35271152 | Result | Wang Y, Zheng L, Yang J, Wang S. A Grip Strength Estimation Method Using a Novel Flexible Sensor under Different Wrist Angles. Sensors (Basel). 2022 Mar 4;22(5):2002. doi: 10.3390/s22052002. | |
| 36196076 | Result | Han G, Zhou S, Wang W, Li W, Qiu W, Li X, Fan X, Li W. Correlations between paraspinal extensor muscle endurance and clinical outcomes in preoperative LSS patients and clinical value of an endurance classification. J Orthop Translat. 2022 Sep 20;35:81-86. doi: 10.1016/j.jot.2022.08.005. eCollection 2022 Jul. |
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| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| 34366759 | Result | Li Z, Zhang S, Chen Y, Ling H, Zhao L, Luo G, Wang X, Hartel MC, Liu H, Xue Y, Haghniaz R, Lee K, Sun W, Kim H, Lee J, Zhao Y, Zhao Y, Emaminejad S, Ahadian S, Ashammakhi N, Dokmeci MR, Jiang Z, Khademhosseini A. Gelatin methacryloyl-based tactile sensors for medical wearables. Adv Funct Mater. 2020 Dec 1;30(49):2003601. doi: 10.1002/adfm.202003601. Epub 2020 Sep 6. |
| 34542672 | Result | Hodges PW, Bailey JF, Fortin M, Battie MC. Paraspinal muscle imaging measurements for common spinal disorders: review and consensus-based recommendations from the ISSLS degenerative spinal phenotypes group. Eur Spine J. 2021 Dec;30(12):3428-3441. doi: 10.1007/s00586-021-06990-2. Epub 2021 Sep 20. |