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The investigators present a pilot diet intervention study, to be conducted as a within-subject design, to assess the feasibility of iron biofortified microgreens on iron intake and status in women of reproductive age and postmenopausal women. This will be investigated by providing smoothie kits for 28 days containing these microgreens and determining the impact on iron biomarkers. The investigators will also assess habitual diet, BMI, physical activity and gastrointestinal symptoms. This study will be a proof-of-concept exploratory study to explore diet based biofortification through vertical farming systems.
In this study microgreens that were grown using agronomic iron biofortification will be supplied to women to add to their diet to establish the potential nutritional impact of iron biofortified microgreens on overall iron intake and iron status. Furthermore, it will assess the adherence to the provided consumption recommendations of the biofortified crops.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vertigreens | Experimental | Phase 1: Habitual diet (1 week) Phase 2: Vertigreens diet: One smoothie a day containing biofortified microgreens (4 weeks) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Smoothie containing iron biofortified microgreens | Other | 30g of iron biofortified microgreens consumed within a smoothie for 28 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Haemoglobin status change from baseline | Iron status changes in haemoglobin | Measured at study day 1 and on study day 28 |
| Serum iron status change from baseline | Iron status changes in serum iron | Measured at study day 1 and on study day 28 |
| Ferritin status change from baseline | Iron status changes in ferritin | Measured at study day 1 and on study day 28 |
| CRP change from baseline | Changes in CRP | Measured at study day 1 and on study day 28 |
| Dietary iron intake changes compared to habitual diet | Dietary iron intake changes in iron intake compared to habitual diet measured though food diaries | every study day (28 days) |
| Measure | Description | Time Frame |
|---|---|---|
| Serum Vitamin B12 status change from baseline | Vitamin B12 status changes | Measured on study day 1 and on study day 28 |
| Adherence to consumption of microgreens/smoothie | intake measured through food diaries |
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Inclusion Criteria:
Exclusion Criteria:
Medication exclusion criteria:
Medical exclusion criteria:
Other exclusion criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alexandra Johnstone, Prof | University of Aberdeen, Rowett Institute of Nutrition and Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rowett Institute, University of Aberdeen | Aberdeen | AB25 2ZD | United Kingdom |
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| every study day (28 days) |