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The CA-800 Corneal Analyzer (Visia Imaging S.R.L., Italy) is a device that can measure small imperfections in the tear film when the eyes are open. The goal of this study is to see if the device can detect changes in the tear film after instillation of an eye drop or when contact lenses are worn.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental: Systane Complete / Senofilcon A/ Somofilcon A | Experimental | On the first day of the study, one drop of Systane Complete will be instilled in each eye. On the second day of the study, senofilcon A will be worn in both eyes. On the third day of the study, somofilcon A will be worn in both eyes. |
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| Experimental: Systane Complete/ Somofilcon A/ Senofilcon A | Experimental | On the first day of the study, one drop of Systane Complete will be instilled in each eye. On the second day of the study, somofilcon A will be worn in both eyes. On the third day of the study, senofilcon A will be worn in both eyes. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Systane Complete Preservative-Free | Drug | One drop of Systane Complete Preservative Free will be instilled in each eye. Higher order aberrations assessed before and after instillation. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in higher order aberrations with an eye drop | The change in root mean square (measured in microns) was assessed over 20 seconds. Data from the right eye was analyzed. | Baseline (prior to instillation); immediately, 10, 20, 30, and 60 minutes post instillation of an eye drop |
| Change in higher order aberrations with senofilcon A | The change in root mean square (measured in microns) was assessed over 20 seconds. Data from the right eye was analyzed. | Baseline (prior to insertion); immediately, 30 minutes, and 6 hours post insertion of a contact lens |
| Change in higher order aberrations with somofilcon A | The change in root mean square (measured in microns) was assessed over 20 seconds. Data from the right eye was analyzed. | Baseline (prior to insertion); immediately, 30 minutes, and 6 hours post insertion of a contact lens |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lyndon Jones, PhD, DSc, FCOptom | Centre for Ocular Research & Education | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre for Ocular Research & Education | Waterloo | Ontario | N2L 3G1 | Canada |
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| Senofilcon A | Device | Daily disposable silicone hydrogel contact lenses indicated for myopia or hyperopia. Higher order aberrations assessed before and after instillation. |
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| Somofilcon A | Device | Daily disposable silicone hydrogel contact lenses indicated for myopia or hyperopia. Higher order aberrations assessed before and after instillation. |
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