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Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients. One group assigned for placement of xenograft after molar extraction and immediate implant placement, while the other group received allograft as space-filling material.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Xenograft | Active Comparator |
| |
| Allograft | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Xenograft | Procedure | The jumping gap and surrounding space will be augmented and packed with Xenograft |
|
| Measure | Description | Time Frame |
|---|---|---|
| Horizontal bone thickness in millimeters | Two CBCT images will be taken, one immediately after surgery (baseline) and the other at 6 months post-surgically | 6 months postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Vertical bone height in millimeters | Two CBCT images will be taken, one 2 days after surgery (baseline) and the other at 6 months post-surgically | 6 months postoperative |
| Pain intensity | The pain will be recorded by participants at 1, 3, and 7 days after surgery using the Visual Analogue Scale (VAS), which ranges from 0 to 10. The minimum score is 0, indicating no pain, and the maximum score is 10, representing the worst possible pain. Higher scores on the VAS indicate worse outcomes in terms of pain experienced. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed Mohamed Tawfik, BSc | Contact | +201095544285 | ahmed-tawfik@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Mohamed Atef, PhD | Cairo University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, Cairo University | Cairo | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12562363 | Background | Botticelli D, Berglundh T, Buser D, Lindhe J. The jumping distance revisited: An experimental study in the dog. Clin Oral Implants Res. 2003 Feb;14(1):35-42. doi: 10.1034/j.1600-0501.2003.140105.x. | |
| 18761580 | Background | Bhola M, Neely AL, Kolhatkar S. Immediate implant placement: clinical decisions, advantages, and disadvantages. J Prosthodont. 2008 Oct;17(7):576-81. doi: 10.1111/j.1532-849X.2008.00359.x. Epub 2008 Aug 26. |
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|---|---|
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| ID | Term |
|---|---|
| D014183 | Transplantation, Heterologous |
| D014184 | Transplantation, Homologous |
| ID | Term |
|---|---|
| D014180 | Transplantation |
| D013514 | Surgical Procedures, Operative |
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This trial is considered a randomized single blind clinical trial due to the following:
| Allograft | Procedure | The jumping gap and surrounding space will be augmented and packed with Allograft |
|
| One week postoperative |
| 22211305 | Background | Lang NP, Pun L, Lau KY, Li KY, Wong MC. A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res. 2012 Feb;23 Suppl 5:39-66. doi: 10.1111/j.1600-0501.2011.02372.x. |
| 21704997 | Background | Dimitriou R, Mataliotakis GI, Angoules AG, Kanakaris NK, Giannoudis PV. Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review. Injury. 2011 Sep;42 Suppl 2:S3-15. doi: 10.1016/j.injury.2011.06.015. Epub 2011 Jun 25. |
| 26009921 | Background | Khoury F, Hanser T. Mandibular bone block harvesting from the retromolar region: a 10-year prospective clinical study. Int J Oral Maxillofac Implants. 2015 May-Jun;30(3):688-97. doi: 10.11607/jomi.4117. |
| 18181932 | Background | Schropp L, Isidor F. Timing of implant placement relative to tooth extraction. J Oral Rehabil. 2008 Jan;35 Suppl 1:33-43. doi: 10.1111/j.1365-2842.2007.01827.x. |
| 33438320 | Background | Alexopoulou M, Lambert F, Knafo B, Popelut A, Vandenberghe B, Finelle G. Immediate implant in the posterior region combined with alveolar ridge preservation and sealing socket abutment: A retrospective 3D radiographic analysis. Clin Implant Dent Relat Res. 2021 Feb;23(1):61-72. doi: 10.1111/cid.12974. Epub 2021 Jan 13. |
| 30904559 | Background | Howe MS, Keys W, Richards D. Long-term (10-year) dental implant survival: A systematic review and sensitivity meta-analysis. J Dent. 2019 May;84:9-21. doi: 10.1016/j.jdent.2019.03.008. Epub 2019 Mar 20. |
| 6809663 | Background | Adell R, Lekholm U, Rockler B, Branemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg. 1981 Dec;10(6):387-416. doi: 10.1016/s0300-9785(81)80077-4. |
| 31370168 | Background | Kononen E, Gursoy M, Gursoy UK. Periodontitis: A Multifaceted Disease of Tooth-Supporting Tissues. J Clin Med. 2019 Jul 31;8(8):1135. doi: 10.3390/jcm8081135. |
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