In intensive care units, sepsis, which can be defined as bacteremia and the irregular and uncontrolled inflammatory response to it, is one of the most important causes of mortality. Early recognition of sepsis and appropriate antibiotic use for the causative agent is one of the most important steps in the fight against sepsis. Procalcitonin (PCT) is a calcitonin precursor peptide and has been reported to predict bacteremia early. While the PCT concentration level is negligible in healthy individuals, it has been shown to increase especially in bacterial infections, sepsis, trauma and burns. In our study, our aim is to determine whether there is a relationship between serum PCT concentration levels taken within 24 hours according to the time of the sample taken for blood culture with growth in patients followed up in our Internal Intensive Care Unit.

Inclusion Criteria:

• Positive blood culture during their follow up
• Patients over 18 years of age

Exclusion Criteria:

• Those under the age of 18
• Those who have had surgery or trauma in the last 72 hours
• Those with a history of autoimmune disease, chronic renal failure
• Patients admitted to intensive care due to acute pancreatitis, pregnancy, burns.
• Patients with incomplete data.

Among the patients who were followed up in the intensive care unit between 01.01.2018 and 01.01.2023 and who were found to have a positive blood culture during their follow up, only those whose PCT results were obtained within 24 hours, based on the time the blood culture sample was taken, will be included.

Data to be Shared:

Anonymized individual patient data (demographic information, laboratory results, culture results, clinical scores and mortality status).

Sharing Time:

After the study is completed and the results are published

Sharing Conditions:

Requests with ethics committee approval and scientific purposes will be evaluated with a written application. Data sharing will be done via e-mail or secure systems by signing a data usage protocol.

Sharing Scope:

Only anonymous data will be shared, excluding identifying personal information