Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This randomized controlled trial investigates the comparative effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy and selective serotonin reuptake inhibitors (SSRIs) in fostering post-traumatic growth among patients diagnosed with post-traumatic stress disorder (PTSD). Participants will be randomized to receive either EMDR therapy or standard SSRI pharmacotherapy. The primary objective is to evaluate the extent of psychological growth and recovery achieved through each intervention, aiming to guide future therapeutic strategies for PTSD.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| EMDR | Experimental | EMDR therapy |
|
| SSRIs | Active Comparator | Acting as control group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EMDR | Behavioral | Participants will receive structured EMDR therapy sessions conducted by trained therapists following standard EMDR protocols. Sessions will occur weekly over a 6 week period. |
| Measure | Description | Time Frame |
|---|---|---|
| Post-Traumatic Growth (PTG) measured by Post-Traumatic Growth Inventory (PTGI) | Change in PTGI total score from baseline to 6 weeks. | 6 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| PTSD symptom severity measured by PTSD Checklist | Change in PTSD Checklist total score from baseline to 6 weeks. | 6 weeks |
Not provided
Inclusion Criteria:
Clinical diagnosis of Post-Traumatic Stress Disorder (PTSD) based on DSM-5 criteria
Willingness to participate and provide informed consent
Ability to comply with study procedures
Exclusion Criteria:
Current diagnosis of psychotic disorder, bipolar disorder, or severe major depressive episode with psychotic features
Active substance use disorder within the past 6 months
Severe cognitive impairment or inability to complete study assessments
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Combined Military Hospital | Nowshera | KPK | 25770 | Pakistan | ||
| Department of Psychiatry, Combined Military Hospital Nowshera |
Privacy concerns and confidentiality protections for participants limit the feasibility of public data sharing.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| SSRIs | Drug | Participants will receive pharmacotherapy with an SSRI prescribed according to standard clinical guidelines for PTSD, monitored by a psychiatrist over a 6-week period. |
|
| Nowshera |
| KPK |
| 25770 |
| Pakistan |
| ID | Term |
|---|---|
| D003130 | Combat Disorders |
| D013313 | Stress Disorders, Post-Traumatic |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
| ID | Term |
|---|---|
| D057169 | Eye Movement Desensitization Reprocessing |
| D017367 | Selective Serotonin Reuptake Inhibitors |
| ID | Term |
|---|---|
| D003887 | Desensitization, Psychologic |
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
| D014179 | Neurotransmitter Uptake Inhibitors |
| D049990 | Membrane Transport Modulators |
| D045504 | Molecular Mechanisms of Pharmacological Action |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D018377 | Neurotransmitter Agents |
| D018490 | Serotonin Agents |
| D045505 | Physiological Effects of Drugs |
Not provided
Not provided