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The worldwide incidence of placenta accreta spectrum is increasing, following the trend of rising caesarean delivery. It is an heterogeneous condition associated with a high maternal morbidity and mortality rate (Jauniaux et al., 2018).
caesarean hysterectomy is considered the gold standard for the treatment of placenta accreta. Also this radical approach is associated with high rates of severe maternal morbidity as hemorrhage and insult to surrounding organs during surgery (Hoffman et al., 2010).
Surgeons should be able to dissect the bladder safely and confidently through minimally invasive techniques, to avoid surgical injury, it is important to use anatomic landmarks, minimize the use of cauterization (Farhat and Casale, 2018).
All centers are encouraged to develop guidelines to manage the potential urologic complications of these cases tailored to their resources (Taneja and Shah, 2017).
This study aims to evaluate the timing of bladder dissection in caesarean section in patient with placenta accreta spectrum.
Objective:
Try to provide preliminary data to judge between two different approaches during caesarean section for morbidly adherent placenta, that's are bladder dissection before and after uterine incision as regard operative time, blood loss, and incidence of urological injuries.
Research Question:
- Does bladder dissection after uterine incision in caesarean sections with PAS avoids bladder injuries compared to bladder dissection before uterine incision and does it affects operative time and blood loss.
Research hypothesis:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group A | Active Comparator | 40 patients will have bladder dissection at the start of caesarean section for patient with morbidly adherent placenta |
|
| group b | Active Comparator | 40 patients will have bladder dissection after closing uterine incision and just before clamping uterine artery in case of caesarean hysterectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bladder dissection in placenta accreta spectrum | Procedure | All caesarean sections will be performed by a surgeon who has experience in performing caesarean hysterectomy in both groups.
|
| Measure | Description | Time Frame |
|---|---|---|
| o Blood loss | assessed by number of soaked towels and suction reservoir) | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
o History of urinary bladder injury.
pregnant females
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| salma M hussain, assistan lecturer | Contact | 00201145895970 | salmaa_mohd@hotmail.com | |
| Hatem Elsayed, lecturer | Contact | 00201009525878 |
| Name | Affiliation | Role |
|---|---|---|
| khaled saed, professor | direcror | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19191778 | Background | Eller AG, Porter TF, Soisson P, Silver RM. Optimal management strategies for placenta accreta. BJOG. 2009 Apr;116(5):648-54. doi: 10.1111/j.1471-0528.2008.02037.x. Epub 2009 Feb 4. | |
| 20510963 | Background | Hoffman MS, Karlnoski RA, Mangar D, Whiteman VE, Zweibel BR, Lockhart JL, Camporesi EM. Morbidity associated with nonemergent hysterectomy for placenta accreta. Am J Obstet Gynecol. 2010 Jun;202(6):628.e1-5. doi: 10.1016/j.ajog.2010.03.021. |
| Label | URL |
|---|---|
| pubmed | View source |
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|
| 28599899 | Background | Jauniaux E, Collins S, Burton GJ. Placenta accreta spectrum: pathophysiology and evidence-based anatomy for prenatal ultrasound imaging. Am J Obstet Gynecol. 2018 Jan;218(1):75-87. doi: 10.1016/j.ajog.2017.05.067. Epub 2017 Jun 24. |
| 22071057 | Background | Marshall NE, Fu R, Guise JM. Impact of multiple cesarean deliveries on maternal morbidity: a systematic review. Am J Obstet Gynecol. 2011 Sep;205(3):262.e1-8. doi: 10.1016/j.ajog.2011.06.035. Epub 2011 Jun 15. |
| ID | Term |
|---|---|
| D010921 | Placenta Accreta |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D010922 | Placenta Diseases |
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