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| ID | Type | Description | Link |
|---|---|---|---|
| 2023YFC2507200 | Other Grant/Funding Number | The National Key Research and Development Program of China |
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Right heart catheterization(RHC) plays a crucial role in the diagnosis and treatment of pulmonary vascular diseases(PVD). In China, the lack of equipment and technical expertise has historically limited the implementation of RHC, thereby greatly restricting the diagnosis and treatment of RVD. In recent years, with improvements in these issues, more hospitals have acquired the capability to perform RHC. The purpose of this study is to conduct quality control of RHC across multiple pulmonary hypertension(PH) centers in China. The study population consists of patients who underwent RHC for the first time due to dyspnea or suspected PH. This study retrospectively and prospectively collects multicenter RHC data, with the main quality control contents including indications for the procedure, collection and analysis of hemodynamic data, diagnosis and treatment, and long-term management of patients.
This study is led by the China-Japan Friendship Hospital and will be conducted across approximately 30 pulmonary hypertension centers in China. It is an observational cohort study without interventional treatment. Eligible participants are patients aged 14 years or older who undergo right heart catheterization due to dyspnea or suspected pulmonary hypertension. After study initiation, investigators at each center will enroll eligible patients and collect baseline data, hemodynamic parameters from right heart catheterization, diagnostic classification of pulmonary hypertension, and treatment plans. Patients will receive routine follow-up at their respective centers, and investigators will gather follow-up data according to the study protocol. All de-identified data will be recorded in an Electronic Data Capture (EDC) system. A dedicated data management team will oversee data management, quality control, and statistical analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients who underwent right heart catheterization | The study population consists of patients who underwent right heart catheterization for the first time due to dyspnea or suspected pulmonary hypertension. No intervention. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention; Observational study | Other | No intervention; observational study |
|
| Measure | Description | Time Frame |
|---|---|---|
| 3-month all cause death | 3-month all cause death | 3 month |
| Measure | Description | Time Frame |
|---|---|---|
| dignosis and type of pulmonary hypertension | dignosis and type of pulmonary hypertension according to latest guidelines | 1 month |
| 1-year all cause death | 1-year all cause death |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who underwent right heart catheterization for the first time due to dyspnea or suspected pulmonary hypertension and age over 14 years old
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhenguo Zhai | Contact | 010-8420-6265 | zhaizhenguo2011@126.com | |
| Yu Zhang, MD | Contact | +8613120211583 | zhangyuccmu2013@yeah.net |
| Name | Affiliation | Role |
|---|---|---|
| Zhenguo Zhai, PhD | China-Japan Friendship Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| China-Japan Friendship Hospital | Recruiting | Beijing | China |
We retain the property rights to the patient-level data, and therefore will not share this data. We plan to publish the study results and provide aggregate data when necessary.
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blood sample
| 1 year |
| ID | Term |
|---|---|
| D006976 | Hypertension, Pulmonary |
| D011655 | Pulmonary Embolism |
| D004194 | Disease |
| D000081029 | Pulmonary Arterial Hypertension |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D006973 | Hypertension |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D004617 | Embolism |
| D016769 | Embolism and Thrombosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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