Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale

Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale

To establish a headache center in China that combines clinical, imaging and laboratory examinations, explore the feasible treatment options for migraine combined with patent foramen ovale, and search for the possible influencing factors, construct models that influence prognosis.

Inclusion Criteria:

• Meet the diagnostic criteria for migraine in the International Classification of Headache (ICHD-3);
• Confirmation of patent foramen ovale through transthoracic echocardiography(TTE) or transesophageal echocardiography(TEE)/right heart contrast echocardiography
• Agree to participate in the study and sign the informed consent form.

Exclusion Criteria:

• Can not sign the informed consent form or cooperate with follow-up.