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Ten years after our team's publication, practices have changed considerably in the management of severe cirrhotic patients. This study will analyse these practices in primary care hospitals and in a tertiary centre, and assess the impact of these changes on the prognosis of these patients.
The following hypotheses will be tested:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| observational study | Other | This observational study aims to describe the clinical practices and the outcome of patients admitted in ICU. |
| Measure | Description | Time Frame |
|---|---|---|
| 28-day survival | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Phenotype of patients admitted to intensive care | baseline | |
| Overall survival | through study completion | |
| Survival without liver transplantation |
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Inclusion Criteria:
Patients with cirrhosis over 18 years of age (cirrhosis either histologically proven or diagnosed by hepatologists according to clinical, biological and ultrasound criteria) admitted to intensive care between January 2014 and December 2024.
Exclusion Criteria:
None
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Patients with cirrhosis admitted to intensive care between January 2014 and December 2024.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Besançon | Recruiting | Besançon | 25000 | France |
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| 12 months |
| Proportion of patients listed for liver transplantation | through study completion |
| number of patients receiving LT | through study completion |
| Prognostic performance of general and cirrhosis-specific organ failure scores | baseline |
| Comparison of the characteristics of patients on admission in primary care hospitals and in university hospital. | baseline |
| ID | Term |
|---|---|
| D005355 | Fibrosis |
| D065290 | Acute-On-Chronic Liver Failure |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D017114 | Liver Failure, Acute |
| D017093 | Liver Failure |
| D048550 | Hepatic Insufficiency |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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