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The purpose of this study is to investigate which flow rate (higher versus lower) is most effective at increasing apneic time and preventing greater than 5% drop in desaturation, as well as assessing transcutaneous carbon dioxide (CO2) levels during airway procedures in children
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High flow | Experimental |
| |
| Low Flow | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High flow | Device | The High Flow Nasal Cannula (HFNC) device (Vapotherm) will be placed through the nostrils for oxygen (2L/kg per min with max of 45L) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants that show an incidence of oxygen desaturation >5 % | from start of procedure to end of procedure (about 1 hour) |
| Measure | Description | Time Frame |
|---|---|---|
| Apnea time measured in seconds or minutes | from start of procedure to end of procedure (about 1 hour) | |
| Number of Participants With Surgical Interruptions Due to Desaturation | Number of surgical interruptions due to desaturation defined by a pause in surgical procedures due to need to provide airway intervention to improve patient's oxygen saturation, normalized to case length. Airway interventions may include LMA, bag mask ventilation, and/or endotracheal intubations |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhen Huang, MD | Contact | (713) 500-5419 | Zhen.J.Huang@uth.tmc.edu | |
| Candace Hernandez | Contact | (713) 500-5410 | Candace.Hernandez@uth.tmc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Zhen Huang, MD | The University of Texas Health Science Center, Houston | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | United States |
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| Low Flow | Device | The High Flow Nasal Cannula (HFNC) device (Vapotherm) will be placed through the nostrils for oxygen (0.5L/kg per min with max of 5L) |
|
| from start of procedure to end of procedure (about 1 hour) |
| Oxygen nadir level | from start of procedure to end of procedure (about 1 hour) |
| Transcutaneous CO2 measurements throughout procedure | from start of procedure to end of procedure (about 1 hour) |
| Adverse events related to device itself (nasal pain, skin irritation) | from baseline to end of study (1 month after baseline) |