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In the included patients, after complete removal of caries from the entire cavity, the exposed pulp will be treated with either a 2.5% NaOCl or 0.1% Octenidine solution. Subsequently, the cavity will be restored using calcium silicate cement, glass ionomer cement, and composite resin. Postoperatively, the patient's pain level will be assessed using the Visual Analogue Scale (VAS) at 24 and 72 hours, as well as on the 7th day. Responses to pulp sensitivity tests and periapical radiographs will be evaluated at 6 months.
After obtaining a detailed pain history from the patients and conducting clinical and radiographic examinations, if a case is deemed suitable for the study, patients will be informed about the possibility of participating in this research project and the procedures involved. The risks and benefits associated with the study will be explained to the patients. Once a patient is considered a potential candidate for the study and expresses interest in participation, informed consent will be obtained.
Before the caries removal procedure, local anesthesia will be administered, and the teeth will be isolated using a rubber dam. Cavities will be prepared using a diamond bur under continuous water cooling. Caries will be completely removed from the entire cavity with the help of steel round burs and excavators, continuing until hard dentin is reached. Bleeding from the exposed pulp will be controlled by pressing a cotton pellet soaked in sterile physiological saline onto the exposure site for one minute. At this point, a researcher not involved in this study will provide the treating clinician with a glass dish containing either a 2.5% NaOCl or 0.1% Octenidine solution. A cotton pellet soaked in the test or control solution will be applied to the exposed pulp, and the cavity will be gently wiped. The cavity will be restored using calcium silicate cement, glass ionomer cement, and composite resin. Postoperatively, the patient's pain levels will be assessed using the Visual Analogue Scale (VAS) at 24 and 72 hours, as well as on the 7th day. Pulp sensitivity tests and periapical radiographs will be conducted at 6 months to evaluate the outcome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Octenidine | Experimental | A cotton pellet soaked in 0.1% Octenidine will be applied to the exposed pulp area |
|
| NaOCl | Experimental | A cotton pellet soaked in 2.5% NaOCl will be applied to the exposed pulp area |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pulp lavage Octenidine | Other | Use of Octenidine as a pulp irrigation solution in pulp capping for mature permanent teeth |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post operative pain | Use of the Visual Analog Scale (VAS) following the procedure | 24 hours |
| Post operative pain | Use of the Visual Analog Scale (VAS) following the procedure | 48 hours |
| Post operative pain | Use of the Visual Analog Scale (VAS) following the procedure | 72 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Pulp vitality-ct | Evaluation through cold testing | 6 months |
| Pulp vitality-ept | Evaluation through electric pulp testing | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Cemre Koç | Aydın Adnan Menderes University, Faculty of Dentistry | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cemre Koç | Aydin | Efeler | 09100 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D003789 | Dental Pulp Exposure |
| ID | Term |
|---|---|
| D003788 | Dental Pulp Diseases |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| pulp lavage NaOCl | Other | Use of NaOCl as a pulp irrigation solution in pulp capping for mature permanent teeth |
|
| Pulp vitality-pr | Evaluation through periapical radiographic examinations | 6 months |