Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging

Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging

The goal of this observational study is to evaluate the role and effect of 18F-FAPI PET imaging in the identification of intestinal lesions and the assessment of disease activity in inflammatory bowel disease. The main question it aims to answer is:

Can 18F-FAPI PET imaging effectively identify intestinal lesions in inflammatory bowel disease and accurately assess disease activity? Colonoscopy, enhanced abdominal CT, and 18F-FAPI intestinal imaging were completed within 1 week, and major adverse outcomes (MAO) were followed up 12 months after enrollment.

Last updated on March 25, 2025

Inclusion Criteria:

• Patients diagnosed with IBD according to clinical, imaging, endoscopic, and histopathological criteria;
• Patients ≥18 years old;
• 18F-FAPI PET/CT intestinal imaging, conventional endoscopic and enhanced CT were performed within 1 week;
• Intestinal segment matching was evaluated by endoscopy and imaging;
• Patients voluntarily participate and sign informed consent.

Exclusion Criteria:

• Pregnant or lactating patients;
• Imaging images are of poor quality and cannot be used for diagnosis and evaluation;
• Patients with contraindications for endoscopic or CT examination.