Comparison of Prostate Cancer-related Quality of Life in Sexually Active Men With Favourable Intermediate-risk Localised Prostate Cancer Treated With Total Prostatectomy or Focal HIFU

Comparison of Prostate Cancer-related Quality of Life in Sexually Active Men With Favourable Intermediate-risk Localised Prostate Cancer Treated With Total Prostatectomy or Focal HIFU

The goal of this trial is to assess the impact of focal HIFU therapy on quality of life in patients with favourable intermediate-risk localised prostate cancer. The main question it aims to answer is:

What is the prostate cancer-related quality of life in patients with favourable intermediate-risk localised cancer treated by total prostatectomy or focal HIFU ?

Researchers will compare patients with favourable intermediate-risk localised cancer treated by total prostatectomy to patients with favourable intermediate-risk localised cancer treated by focal HIFU to see their quality of life.

Participants will answer EPIC-CP questionnaire 6 months, 12 months and 24 months after treatment

Inclusion Criteria:

• Patient, male, aged between ≥ 40 and ≤ 75 years
• Patient with a life expectancy > 10 years at the time of inclusion.
• Patient with a therapeutic strategy (prostatectomy or focal HIFU) defined during a PCR.
• Patient with a diagnosis of localised prostate cancer at favourable intermediate risk
• Patient able to tolerate general anaesthesia or type IV sedation
• Patient with normal urinary continence status
• Patient with satisfactory erectile function allowing penetration:
• Patient with targeted biopsies and systematic biopsies
• Patient affiliated to or benefiting from a social security scheme
• French-speaking patients who do not object to the use of their data.

Exclusion Criteria:

• Patients with a contraindication to MRI
• Stage T3a or b on MRI
• Patient on long-term anticoagulants and unable to stop them.
• Patient already included in another study
• Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision