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Eligible participants will first undergo a 1-week home blood pressure diary and 24-hour ambulatory blood pressure assessment. After a confirmed diagnosis of hypertension, etiological subtyping will be performed. Based on the blood pressure evaluation results and etiological classification, the most appropriate antihypertensive medication will be selected. Simultaneously, a personalized lifestyle prescription will be provided according to the patient's individual circumstances. Following medication initiation, participants will continue to monitor their blood pressure through home diaries. Monthly evaluations will be conducted, and if blood pressure fails to reach the target value, medication adjustments will be made based on the blood pressure diary until target levels are achieved. This regimen will be maintained long-term.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hypertension precision diagnosis and treatment group | Experimental | participants will undergo etiological testing for primary hypertension, followed by tailored pharmacological treatment and digital blood pressure monitoring, with regular medication adjustments. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Etiological Classification and Digital Intervention | Other | Eligible participants will first undergo a 1-week home blood pressure diary and 24-hour ambulatory blood pressure assessment. After a confirmed diagnosis of hypertension, etiological subtyping will be performed. Based on the blood pressure evaluation results and etiological classification, the most appropriate antihypertensive medication will be selected. Simultaneously, a personalized lifestyle prescription will be provided according to the patient's individual circumstances. Following medication initiation, participants will continue to monitor their blood pressure through home diaries. Monthly evaluations will be conducted, and if blood pressure fails to reach the target value, medication adjustments will be made based on the blood pressure diary until target levels are achieved. This regimen will be maintained long-term. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Blood Pressure Recorded in a 1-Week Home Blood Pressure Diary | Changes in blood pressure recorded (SBP/DBP) in a 1-week home blood pressure diary from baseline to 3 months. | 3 months following intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Change in 24-hour Ambulatory Blood Pressure Monitoring | Change in 24-hour ambulatory blood pressure monitoring (daytime, nighttime, and overall SBP/DBP) at 1/2 /3 months. | 1/2/3 months following intervention |
| Change in Home Blood Pressure Monitoring |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yi Zhang | Contact | 18917686332 | yizshcn@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Cardiology, Shanghai Tenth People's Hospital | Shanghai | Shanghai Municipality | 200072 | China |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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Change in home blood pressure monitoring (SBP/DBP) at 1/2months.
| 1/2 months following intervention |
| Control Rate | Proportion of patients achieving target blood pressure at 3 months. | 3 months following intervention |
| Drug adjustment times | The total number of times to adjust blood pressure medication in 3 months | 3 months following intervention |
| Shanghai Tenth People's Hospital | Shanghai | Shanghai Municipality | 200092 | China |