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| ID | Type | Description | Link |
|---|---|---|---|
| 2025-A00267-42 | Other Identifier | ID-RCB |
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| Name | Class |
|---|---|
| IHU reConnect | UNKNOWN |
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The goal of this observational study is to understand the mechanisms underlying tinnitus, and improve the clinical assessment strategies needed to develop targeted therapeutic interventions by comparing endogenous attention capacities in healthy subjects and subjects with tinnitus
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy subjects | Sham Comparator |
| |
| Subjets with tinnitus | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Quality of Life questionnaires | Other | Subjects will complete a number of self-questionnaires on subjects such as attention span, anxiety levels and sleep quality. |
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| Measure | Description | Time Frame |
|---|---|---|
| Contingent negative variation (CNV) in EEG | 2 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Response reaction time (in ms) | Comparison of reaction time (RT) variability following response button presses in behavioural tasks | 2 hours |
| Answer accuracy (% correct answers) | Comparison of the variability of the number of correct responses following button presses in behavioural tasks. |
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Inclusion Criteria:
Group of people with tinnitus :
- Chronic tinnitus > 3 months, uni or bilateral, stable (no period of remission)
Control group :
- No tinnitus
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Séverine Samson | Contact | +33 (0)1 76 53 51 44 | severine.samson@pasteur.fr |
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| ID | Term |
|---|---|
| D014012 | Tinnitus |
| ID | Term |
|---|---|
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012678 | Sensation Disorders |
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| ID | Term |
|---|---|
| D006309 | Hearing |
| ID | Term |
|---|---|
| D000084323 | Vestibulocochlear Physiological Phenomena |
| D010829 | Physiological Phenomena |
| D012677 | Sensation |
| D009424 | Nervous System Physiological Phenomena |
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| Hearing tests | Other | listening to sounds on headphones and repeating words |
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| Auditory prediction task | Behavioral | listening to sounds and assessing auditory perception |
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| Attention task | Behavioral | assessment of reaction time to visual or auditory cues |
|
| 2 hours |
| Cerebral oscillations (alpha bands) obtained by EEG during behavioural tasks | 2 hours |
| Skin conductance (μS) | during behavioral task | 2 hours |
| Heart rate variability (in ms) | during behavioral task | 2 hours |
| Pupillometry (pupillary dilation in mm) | 2 hours |
| D009461 |
| Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |