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To evaluate the clinical efficacy of a Dual Zinc Toothpast containing 5% small particle size silica (AC43) as compared to Colgate MaxFresh Tea Toothpaste on dentin hypersensitivity reduction after brushing two times daily (morning and evening) for a period of 8 weeks
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test 1 toothpaste | Experimental | Subjects will be instructed to brush their teeth with their assigned test dentifrice and toothbrush twice daily |
|
| Control toothpaste | Active Comparator | Subjects will be instructed to brush their teeth with their assigned test dentifrice and toothbrush twice daily |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Test toothpaste | Drug | A commercially available fluoride toothpaste |
| |
| Measure | Description | Time Frame |
|---|---|---|
| tactile sensitivity | tactile stimulation is measured by the Yeaple Electronic Force Sensing Probe | baseline and 8 week measurement |
| air blast sensitivity | air blast sensitivity is delivered by a standard dental unit syringe at a measured temperature of 19-21°C (70°F [± 3°F]) [sensitivity will be defined by a score of 2 or 3 on the Schiff Cold Air sensitivity scale Air Sensitivity Scale](streamdown:incomplete-link) | baseline and 8 week measurement |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Deyu Hu, DDS, MS | West China Dental Institute of Chengdu | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West China Dental Institute of Chengdu | Chengdu | Sichuan | 610041 | China |
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| ID | Term |
|---|---|
| D006967 | Hypersensitivity |
| ID | Term |
|---|---|
| D007154 | Immune System Diseases |
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| Control toothpaste |
| Drug |
A commercially available fluoride toothpaste |
|