A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of... | NCT06935370 | Trialant

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of... | NCT06935370 | Trialant

Official Title: EASi-HF Reduced - A Phase III Double-blind, Randomised, Parallel-group Superiority Trial to Evaluate Efficacy and Safety of the Combined Use of Oral Vicadrostat (BI 690517) and Empagliflozin Compared With Placebo and Empagliflozin in Participants With Symptomatic Chronic Heart Failure (HF: NYHA II-IV) and Left Ventricular Ejection Fraction (LVEF) < 40%
Brief Summary: This study is open to adults with chronic heart failure (HF) who have a reduced left ventricular ejection fraction (LVEF) of less than 40%. People can join the study if they have been diagnosed with chronic HF at least 3 months before they start on the study. The purpose of this study is to find out whether a medicine called vicadrostat, in combination with another medicine called empagliflozin, helps people with chronic heart failure.

In this study, participants are put into 2 groups randomly. Participants have an equal chance of being in either group. One group takes vicadrostat/empagliflozin tablets, and the other group takes placebo/empagliflozin tablets. Placebo tablets look like vicadrostat tablets but do not contain any medicine. Participants take the study medicines as tablets once a day for between about 6 months and about 3.5 years. During this time, they can continue their regular treatment for heart failure.

Participants can stay in the study as long as they benefit from treatment and can tolerate it, for a maximum of about 3.5 years. During this time, they visit the study site regularly. The exact number of visits is different for each participant, depending on how long they stay in the study. The study staff may also contact the participants by phone for some visits. Participants also regularly answer questions about their well-being. The doctors document when participants experience worsening of their heart failure symptoms, go to hospital due to heart failure or die during the study. The time until these events are observed is compared between the two treatment groups to see whether the treatment works. The doctors also regularly check participants' health and take note of any unwanted effects.

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Eligibility Criteria: Inclusion criteria:

At least 18 years old and at least at the legal age of consent in countries where it is greater than 18 years

Signed and dated written informed consent in accordance with International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use - Good Clinical Practice (ICH-GCP) and local legislation prior to admission to the trial

Male or female participants. Women of childbearing potential (WOCBP) must be ready and able to use highly effective methods of birth control per ICH M3 (R2) that result in a low failure rate of less than 1% per year when used consistently and correctly. A list of contraception methods meeting these criteria and instructions on the duration of their use is provided in the protocol.

Chronic heart failure (HF) diagnosed at least 3 months before Visit 1, and in New York Heart Association (NYHA) classes II to IV at Visit 1, with left ventricular ejection fraction (LVEF) < 40% per local reading (obtained by echocardiography, radionuclide ventriculography, invasive angiography, magnetic resonance imaging (MRI), or computed tomography (CT)).

Elevated N-terminal pro-brain natriuretic peptide (NT-proBNP) at Visit 1, analysed at the central laboratory

Treated according to best possible standard of care (SOC) (disregarding sodium-dependent glucose co-transporter 2 inhibitor (SGLT2i) and mineralocorticoid receptor antagonist (MRA)) in accordance with applicable heart failure (HF) local/international guidelines and judgement of the investigator.

Additional inclusion criteria apply.

Exclusion criteria:

Treatment with an MRA (e.g. spironolactone, eplerenone, finerenone) within 14 days prior to Visit 1 or requiring such treatment before randomisation or planned during the trial based on the judgment of the investigator. Treatment with an MRA should not be discontinued with the intention of study enrolment.

Treatment with amiloride or other potassium-sparing diuretic within 14 days prior to Visit 1 or requiring such treatment before randomisation or planned during the trial based on the judgment of the investigator.

Receiving the following treatments:

A direct renin inhibitor (e.g. aliskiren) at Visit 2

More than one angiotensin-converting enzyme inhibitor (ACEi), angiotensin receptor blocker (ARB) or angiotensin receptor-neprilysin inhibitor (ARNi) used simultaneously at Visit 2

Other aldosterone synthase inhibitors, e.g. baxdrostat at Visit 2 or planned during the trial

Systemic mineralocorticoid replacement therapy (e.g. fludrocortisone) at Visit 2

In case of acute decompensated HF:

i.v. inotrope, i.v. vasodilating drug (e.g. nitrate, nitroprusside), or i.v. natriuretic peptide (e.g. nesiritide, carperitide), or mechanical support (e.g. intra-aortic balloon pump, endotracheal intubation, mechanical ventilation, any ventricular assist device) within 24 hours prior to randomisation

i.v. diuretic with a dose that has been increased/intensified within 6 hours prior to randomisation (a stable dose of an i.v. diuretic is not exclusionary)

Myocardial infarction (MI), transient ischemic attack (TIA), stroke, coronary artery bypass graft surgery (CABG), heart valve surgery/intervention or any other major surgery (major according to the investigator's assessment) within 90 days prior to Visit 2, or scheduled for major elective surgery (e.g. hip replacement, CABG)

Percutaneous coronary intervention (PCI) or any angiography using iodinated contrast agents in the 7 days prior to Visit 2

Heart transplant recipient, awaiting heart transplant, or currently implanted left ventricular assist device (LVAD)

Known cardiomyopathy based on infiltrative diseases (e.g. amyloidosis), accumulation diseases (e.g. haemochromatosis, Fabry disease), muscular dystrophies, hypertrophic obstructive cardiomyopathy or known pericardial constriction, or cardiomyopathy with potentially reversible cause such as stress or peripartum cardiomyopathy or cardiomyopathy induced by chemotherapy within 12 months prior to Visit 1 and until Visit 2

Acute inflammatory heart disease, such as acute myocarditis, within 90 days preceding prior to Visit 1 and until Visit 2 Further exclusion criteria apply.

Cure Clinical ResearchSuspended

Beverly Hills, California 90211, United States

Valley Clinical Trials, Inc.Recruiting

Covina, California 91723, United States

Boehringer IngelheimContact

unitedstates@bitrialsupport.com833-602-2368

North Coast CardiologyNot yet recruiting

Encinitas, California 92024, United States

Merced Vein and Vascular CenterRecruiting

Merced, California 95340, United States

Radin Cardiovascular Medical GroupRecruiting

Newport Beach, California 92663, United States

Amicis Research Center - NordhoffTerminated

Northridge, California 91324, United States

University of California San DiegoNot yet recruiting

San Diego, California 92103, United States

Paradigm Clinical Research - San DiegoRecruiting

San Diego, California 92108, United States

Amicis Research CorporateTerminated

Santa Clarita, California 91355, United States

Care Access ResearchRecruiting

Thousand Oaks, California 91360, United States

Bay Area CardiologyRecruiting

Brandon, Florida 33511, United States

Cardiology Associates Research Co.Recruiting

Daytona Beach, Florida 32117, United States

Suncoast Research Associates, LLCRecruiting

Doral, Florida 33172, United States

Malcom Randall VA Medical CenterRecruiting

Gainesville, Florida 32608, United States

Velocity Clinical Research-Hallandale Beach-67888Recruiting

Hallandale, Florida 33009, United States

University of FloridaRecruiting

Jacksonville, Florida 32209, United States

East Coast Institute For Research, LLCRecruiting

Jacksonville, Florida 32216, United States

Jacksonville Center for Clinical ResearchRecruiting

Jacksonville, Florida 32216, United States

University of Miami - Miller School of MedicineRecruiting

Miami, Florida 33125, United States

Infinite Clinical Research IncRecruiting

Miami, Florida 33133, United States

Inpatient Research Clinic, LLCRecruiting

Miami Lakes, Florida 33014, United States

Innovation Medical Research CenterRecruiting

Palmetto Bay, Florida 33157, United States

Peace River Cardiovascular CenterRecruiting

Port Charlotte, Florida 33952, United States

St. Johns Center for Clinical ResearchRecruiting

Saint Augustine, Florida 32086, United States

University of South FloridaRecruiting

Tampa, Florida 33606, United States

Cardiology Partners Clinical Research InstituteRecruiting

Wellington, Florida 33449, United States

Cozy Research LLCRecruiting

Wesley Chapel, Florida 33544, United States

Clinical Site Partners, LLCRecruiting

Winter Park, Florida 32789, United States

Atlanta Clinical Research CentersRecruiting

Atlanta, Georgia 30342, United States

NSC Research IncRecruiting

Johns Creek, Georgia 30024, United States

Northwest Heart Clinical Research, LLCNot yet recruiting

Arlington Heights, Illinois 60005, United States

Illinois Masonic HospitalNot yet recruiting

Chicago, Illinois 60657, United States

Chicago Medical ResearchRecruiting

Hazel Crest, Illinois 60429, United States

Clinical Investigation Specialists, Inc.Recruiting

Libertyville, Illinois 60048, United States

AMR Park RidgeRecruiting

Park Ridge, Illinois 60068, United States

Springfield ClinicRecruiting

Springfield, Illinois 62703, United States

Midwest Cardiovascular Research and Education FoundationRecruiting

Elkhart, Indiana 46514, United States

St. Francis Medical Group-Indiana Heart Physicians, IncRecruiting

Indianapolis, Indiana 46237, United States

Cardiovascular Research of Northwest Indiana, LLCRecruiting

Munster, Indiana 46321, United States

Reid HospitalRecruiting

Richmond, Indiana 47374, United States

The Iowa Clinic, PCRecruiting

West Des Moines, Iowa 50266, United States

University of Kansas Medical CenterNot yet recruiting

Kansas City, Kansas 66160, United States

Kansas Nephrology Research Institute, LLCRecruiting

Wichita, Kansas 67214, United States

Robert J Dole Veterans Affairs Medical CenterRecruiting

Wichita, Kansas 67218, United States

West Houston Area Clinical Trial Consultants, LLCRecruiting

Wichita, Kansas 67226, United States

Heart Clinic of HammondRecruiting

Hammond, Louisiana 70403, United States

Grace Research, LLC-Shreveport-64616Suspended

Shreveport, Louisiana 71105, United States

Ascension Saint Agnes Heart CareRecruiting

Baltimore, Maryland 21229, United States

Metropolitan Cardiovascular ConsultantsRecruiting

Beltsville, Maryland 20705, United States

Capitol Cardiology AssociatesRecruiting

Lanham, Maryland 20706, United States

Cardiology and Vascular Associates - CAVARecruiting

Bloomfield Hills, Michigan 48304, United States

Michigan Healthcare Professionals Pulse CardiologyRecruiting

Farmington Hills, Michigan 48334, United States

Henry Ford Providence HospitalRecruiting

Southfield, Michigan 48075, United States

Michigan Heart, PCRecruiting

Ypsilanti, Michigan 48197, United States

Minneapolis VA Health Care SystemRecruiting

Minneapolis, Minnesota 55417, United States

Mayo Clinic, RochesterRecruiting

Rochester, Minnesota 55905, United States

Regions HospitalRecruiting

Saint Paul, Minnesota 55101, United States

Kansas City VA Medical CenterRecruiting

Kansas City, Missouri 64128, United States

St. Louis Heart and Vascular, P.C.Recruiting

St Louis, Missouri 63136, United States

Be Well Clinical StudiesRecruiting

Omaha, Nebraska 68144, United States

Advanced Heart Care, LLCRecruiting

Bridgewater, New Jersey 08807, United States

Mount Sinai Hospital-New York-52529Recruiting

New York, New York 10019, United States

Icahn School of Medicine at Mount SinaiRecruiting

New York, New York 10029, United States

IMA Clinical Research LenoirRecruiting

Lenoir, North Carolina 28645, United States

Pinehurst Medical Clinic, Inc. - EastRecruiting

Pinehurst, North Carolina 28374, United States

WakeMedRecruiting

Raleigh, North Carolina 27610, United States

Piedmont Healthcare, Inc.Recruiting

Statesville, North Carolina 28625, United States

Wilmington HealthRecruiting

Wilmington, North Carolina 28401, United States

VA Northeast Ohio Healthcare SystemNot yet recruiting

Cleveland, Ohio 44106, United States

K and R Research LLCRecruiting

Marion, Ohio 43302, United States

Cardiology Consultants of PhiladelphiaRecruiting

Yardley, Pennsylvania 19067, United States

Bon Secours Medical Group Greenville Specialty Care, LLCTerminated

Greenville, South Carolina 29607, United States

Pharmatex ResearchRecruiting

Amarillo, Texas 79109, United States

Amarillo Heart Clinical Research Institute, IncorporatedRecruiting

Amarillo, Texas 79124, United States

NextStage Clinical ResearchRecruiting

Beaumont, Texas 77702-1513, United States

Clinical Research Solution, LLCRecruiting

Cypress, Texas 77429, United States

Texas Health Research and Education InstituteRecruiting

Dallas, Texas 75231, United States

Southwest Family Medicine AssociatesRecruiting

Dallas, Texas 75235, United States

Helios CR Inc - Fort WorthRecruiting

Fort Worth, Texas 76104, United States

The Methodist Hospital Research InstituteRecruiting

Houston, Texas 77030, United States

DM Clinical Research - IrvingRecruiting

Irving, Texas 75061, United States

DCOL Center for Clinical ResearchRecruiting

Longview, Texas 75605, United States

North Texas Research AssociatesRecruiting

McKinney, Texas 75071, United States

Revival Research Institute, LLC - McKinneyRecruiting

McKinney, Texas 75071, United States

Texas Institute Of CardiologyRecruiting

McKinney, Texas 75071, United States

Accurate Clinical Research, Inc.Recruiting

Richmond, Texas 77469, United States

Baylor Scott and White HealthRecruiting

Temple, Texas 76508, United States

Northwest Heart CenterRecruiting

Tomball, Texas 77375, United States

NextStage Clinical ResearchRecruiting

Waco, Texas 76712, United States

Carient Heart and VascularRecruiting

Manassas, Virginia 20109, United States

Carilion ClinicRecruiting

Roanoke, Virginia 24014, United States

Inst de Inv Clinicas-Bahia BlancaRecruiting

Bahía Blanca, B8000FTD, Argentina

Hospital Regional de Bahia BlancaRecruiting

Bahía Blanca, B8000, Argentina

Centro de Investigaciones Metabolicas (CINME)Recruiting

Buenos Aires, C1056ABJ, Argentina

CIPRECRecruiting

Buenos Aires, C1061AAS, Argentina

Hospital Italiano de Buenos AiresNot yet recruiting

Ciudad Autonoma Buenos Aires, 1199, Argentina

Boehringer IngelheimContact

argentina@bitrialsupport.com08002667801

Fundacion FavaloroRecruiting

Ciudad Autonoma Buenos Aires, C1093AAS, Argentina

Boehringer IngelheimContact

argentina@bitrialsupport.com08002667801

Mautalen- Salud e InvestigacionRecruiting

Ciudad Autonoma Buenos Aires, C1128AAF, Argentina

Boehringer IngelheimContact

argentina@bitrialsupport.com08002667801

Centro Medico Dra Laura MaffeiRecruiting

Ciudad Autonoma Buenos Aires, C1425AGC, Argentina

Boehringer IngelheimContact

argentina@bitrialsupport.com08002667801

Glenny Corp. S.A. Bioclinica ArgentinaRecruiting

Ciudad Autonoma Buenos Aires, C1430CKE, Argentina

Boehringer IngelheimContact

argentina@bitrialsupport.com08002667801

Clinica Coronel SuarezRecruiting

Coronel Suárez, B7540GHD, Argentina

Sanatorio AllendeRecruiting

Córdoba, 5000, Argentina

Sanatorio Privado Duarte Quiros De Clinica Colombo SARecruiting

Córdoba, X5002AOQ, Argentina

Well MedicaRecruiting

Córdoba, X5002HWE, Argentina

Instituto Médico DAMIC S.R.L.Recruiting

Córdoba, X5003DCE, Argentina

Centro Medico LuquezRecruiting

Córdoba, X5006CBI, Argentina

Centro de Investigaciones Clinicas BaigorriaRecruiting

Granadero Baigorria, 2152, Argentina

Centro de Investigaciones Medicas Mar del PlataRecruiting

Mar del Plata, 7600, Argentina

Hospital Universitario AustralRecruiting

Pilar, B1629ODT, Argentina

Instituto Medico CERNot yet recruiting

Quilmes, B1878DVB, Argentina

Instituto de Investigaciones Clinicas de QuilmesRecruiting

Quilmes, B1878GEG, Argentina

DIM Clinica PrivadaRecruiting

Ramos Mejía, 1704, Argentina

INECO Neurociencias OroñoRecruiting

Rosario, 2000, Argentina

Instituto de Investigaciones Clinicas de RosarioRecruiting

Rosario, 2000, Argentina

Instituto Medico Fundacion Grupo Colaborativo Rosario Investigacion y Prevencion MedicaRecruiting

Rosario, 2000, Argentina

Sanatorio Parque S.A.Recruiting

Rosario, S2000DSV, Argentina

Instituto CAICIRecruiting

Rosario, S2000PBJ, Argentina

Investigaciones Clinicas Salta (ICSAL)Recruiting

Salta, 4400, Argentina

Centro Cardiovascular SaltaNot yet recruiting

Salta, A4406BFP, Argentina

Corporacion Medica de Gral. San Martin S.A.Recruiting

San Martin, B1650CSQ, Argentina

Investigaciones en Patologias RespiratoriasRecruiting

San Miguel de Tucumán, T4000IAI, Argentina

Investigaciones Clinicas TucumanRecruiting

San Miguel de Tucumán, T4000ICL, Argentina

Centro Integral de Arritmias TucumanRecruiting

San Miguel de Tucumán, T4000, Argentina

Centro Modelo de CardiologiaRecruiting

San Miguel de Tucumán, T4000, Argentina

Clinica MayoRecruiting

San Miguel de Tucumán, T4000, Argentina

Instituto de Investigaciones Clinicas San NicolasRecruiting

San Nicolás, B2900DMH, Argentina

Hospital "Dr. José Maria Cullen"Recruiting

Santa Fe, S3000EOZ, Argentina

Centro de Investigaciones Clinicas del LitoralRecruiting

Santa Fe, S3000FWO, Argentina

CEMEDIC - Centro de Especialidades MedicasRecruiting

Villa Luro, C1440CFD, Argentina

AZ Sint-BlasiusRecruiting

Dendermonde, 9200, Belgium

Ziekenhuis Oost-LimburgRecruiting

Genk, 3600, Belgium

AZ Sint-LucasRecruiting

Ghent, 9000, Belgium

Grand Hôpital de CharleroiRecruiting

Gilly, 6060, Belgium

C.H.U. de TivoliRecruiting

La Louvière, 7100, Belgium

CHR de la CitadelleRecruiting

Liège, 4000, Belgium

Hospital Sirio LibanesRecruiting

Bela Vista, 01308-050, Brazil

Hospital Felicio RochoRecruiting

Belo Horizonte, 30110-934, Brazil

Cardresearch Cardiologia Assistencial e de Pesquisas LtdaRecruiting

Belo Horizonte, 30150-274, Brazil

L2IP -Instituto de Pesquisas Clínicas Ltda.Recruiting

Brasília, 70200-730, Brazil

Hospital DF StarRecruiting

Brasília, 70390-140, Brazil

CECAP - Centro de Cardiologia ClínicaRecruiting

Brasília, 70710-100, Brazil

Hospital Angelina CaronRecruiting

Campina Grande do Sul, 83430-000, Brazil

IPECC - Instituto de Pesquisa Clínica de CampinasRecruiting

Campinas, 13060-080, Brazil

I9 Pesquisas Clinicas - Loema Instituto de Pesquisa Clínica e Consultores SS LtdaRecruiting

Campinas, 13092-133, Brazil

Hospital do RocioRecruiting

Campo Largo, 83606-177, Brazil

Fundacao Universidade de Caxias do SulRecruiting

Caxias do Sul, 95070-560, Brazil

PUC Trials - Núcleo de Pesquisa Clínica da Escola de Medicina da PUC-PRRecruiting

Curitiba, 80230-130, Brazil

Via MedicaRecruiting

Goiânia, 74223-130, Brazil

HC-UFG - Hospital das Clínicas da Universidade Federal de GoiásRecruiting

Goiânia, 74680160, Brazil

ICM - Instituto do Coracao de MariliaRecruiting

Marília, 17515-000, Brazil

Hospital Vera CruzRecruiting

Minas Gerais, 30220-140, Brazil

Instituto Atena de Pesquisa ClinicaRecruiting

Natal, 59020-035, Brazil

Instituto Mederi de Pesquisa e SaudeRecruiting

Passo Fundo, 99010-120, Brazil

Hospital de Clinicas de Porto AlegreRecruiting

Porto Alegre, 90035-903, Brazil

Irmandade da Santa Casa de Misericórdia de Porto AlegreRecruiting

Porto Alegre, 90050-170, Brazil

Nucleo de Pesquisa Clinica do Rio Grande do Sul (NPCRS)Recruiting

Porto Alegre, 90430-001, Brazil

Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa Sociedade SimplesRecruiting

Porto Alegre, 90840-440, Brazil

Hospital Esperança RecifeRecruiting

Recife, 50070-480, Brazil

Clinicor Clínica Cardiológica LTDA/ Cardio Prime - CAPEDRecruiting

Ribeirão Preto, 14026-900, Brazil

Instituto Brasil de Pesquisa Clinica (IBPClin)Recruiting

Rio de Janeiro, 20241-180, Brazil

Ruschel Medicina e Pesquisa ClínicaRecruiting

Rio de Janeiro, 22270-060, Brazil

Instituto D'Or Pesquisa e Ensino - Rio de JaneiroRecruiting

Rio de Janeiro, 22281-100, Brazil

Hospital Cardio PulmonarRecruiting

Salvador, 40170-310, Brazil

PesquisareRecruiting

Santo André, 09080-110, Brazil

Praxis Pesquisa MedicaRecruiting

Santo André, 09090-970, Brazil

Instituto Domingo BraileRecruiting

São José do Rio Preto, 15015-750, Brazil

Fundação Faculdade Regional de Medicina de São José do Rio PretoRecruiting

São José do Rio Preto, 15090-000, Brazil

CIPES - Centro Internacional de Pesquisa ClínicaRecruiting

São José dos Campos, 12230-001, Brazil

Cpquali Pesquisa Clinica LtdaRecruiting

São Paulo, 01228-000, Brazil

CPCLIN - Centro de Pesquisas Clínicas Ltda.Recruiting

São Paulo, 01228-200, Brazil

CEPIC - Centro Paulista de Investigacao Clinica e ServicosRecruiting

São Paulo, 04266-010, Brazil

Eurolatino Pesquisas Médicas Ltda.Recruiting

Uberlândia, 38400-500, Brazil

CEDOES - Diagnóstico e Pesquisa,VitóriaRecruiting

Vitória, 29055-450, Brazil

Medical center 4LIFE Ltd.Recruiting

Burgas, 8000, Bulgaria

MHAT Heart and brainRecruiting

Burgas, 8000, Bulgaria

Medical Center Doktor Staykov Ltd.Recruiting

Burgas, 8008, Bulgaria

Diamedical Medical Center 2013Recruiting

Dimitrovgrad, 6400, Bulgaria

MHAT "Sveta Ekaterina-Dimitrovgrad", EOODRecruiting

Dimitrovgrad, 6400, Bulgaria

Medical Center New Polyclinic Gabrovo Ltd.Recruiting

Gabrovo, 5300, Bulgaria

MHAT Ivan Skenderov EOODRecruiting

Gotse Delchev, 2900, Bulgaria

Medical Center Rodopimed EOODRecruiting

Kardzhali, 6600, Bulgaria

Medical Center Hera - Kyustendil EOODRecruiting

Kyustendil, 2500, Bulgaria

Tonus 2013 Ltd.Recruiting

Pazardzhik, 4400, Bulgaria

Ambulatory Individual Practice for Cardiology Specialized Medical CareRecruiting

Pernik, 2300, Bulgaria

Medical Center Medconsult Pleven OODRecruiting

Pleven, 5800, Bulgaria

MHAT Heart and brainSuspended

Pleven, 5804, Bulgaria

UMHAT "Sv. Georgi", EADRecruiting

Plovdiv, 4002, Bulgaria

MBAL Sveta Karidad EADRecruiting

Plovdiv, 4004, Bulgaria

Medical Center Rusemed EOODRecruiting

Rousse, 7013, Bulgaria

National Multiprofile Transport Hospital "Tzar Boris III"Recruiting

Sofia, 1233, Bulgaria

Medical Center For Specialized Medical Help In Cardiovascular Diseases OODRecruiting

Sofia, 1309, Bulgaria

University Hospital LozenetzRecruiting

Sofia, 1407, Bulgaria

Alexandrovska University HospitalRecruiting

Sofia, 1431, Bulgaria

Diagnostic Consultative Center AlexandrovskaRecruiting

Sofia, 1431, Bulgaria

University Multidisciplinary Hospital for Active Treatment Sveta Ekaterina EADRecruiting

Sofia, 1431, Bulgaria

Medical Center Hera EOODRecruiting

Sofia, 1510, Bulgaria

UMHAT "Tsaritsa Yoanna-ISUL" EADRecruiting

Sofia, 1527, Bulgaria

ASOMHIDC - Individual practice "Cardio Tonus" EOODRecruiting

Sofia, 1582, Bulgaria

Multiprofile Hospital MHATEM 'Pirogov', SofiaRecruiting

Sofia, 1606, Bulgaria

Diagnostic Consultation Center XX-Sofia EOODRecruiting

Sofia, 1618, Bulgaria

MHAT "St. Sofia"Recruiting

Sofia, 1618, Bulgaria

Kalimat Medical Center Ltd.Recruiting

Sofia, 1680, Bulgaria

Medical Center Intermedica Ltd.Recruiting

Sofia, 1680, Bulgaria

Medical Center Medicabilis Ltd.Recruiting

Sofia, 1756, Bulgaria

Medical center DEA Medicals Ltd.Recruiting

Sofia, Bulgaria

Medical Center Zara-Med EOODRecruiting

Stara Zagora, 6000, Bulgaria

UMHAT Prof. Dr. Stoyan Kirkovich ADRecruiting

Stara Zagora, 6000, Bulgaria

MDHAT 'Dr. Stefan Cherkezov', ADRecruiting

Veliko Tarnovo, 5000, Bulgaria

Medical Center Medica Plus Ltd.Recruiting

Veliko Tarnovo, 5000, Bulgaria

Medical Centre Nevromedics EOODRecruiting

Veliko Tarnovo, 5006, Bulgaria

MHAT St PanteleimonRecruiting

Yambol, 8600, Bulgaria

Saul Vizel Medicine Professional CorporationRecruiting

Cambridge, Ontario N1R 7R1, Canada

Health Sciences NorthRecruiting

Greater Sudbury, Ontario P3E 5J1, Canada

Premier Clinical Trial NetworkRecruiting

Hamilton, Ontario L8L 5G4, Canada

Elevate Clinical Research - KMH HamiltonRecruiting

Kitchener, Ontario N2M 5N4, Canada

KMH Cardiology Centres (Mississauga)Recruiting

Mississauga, Ontario L5K 2L3, Canada

Oakville Trafalgar Memorial HospitalRecruiting

Oakville, Ontario L6K 3W7, Canada

James Cha, MDRecruiting

Oshawa, Ontario L1J 2K1, Canada

Kawartha Cardiology Clinical TrialsRecruiting

Peterborough, Ontario K9J 0B2, Canada

CardioQuest Research CentreRecruiting

Sarnia, Ontario N7T 4P5, Canada

Fadia El Boreky Medicine Professional CorporationRecruiting

Waterloo, Ontario N2J 1C4, Canada

ViaCar Recherches Cliniques Inc. (Brossard)Recruiting

Brossard, Quebec J4Z 2K9, Canada

Diex Recherche (Sherbrooke)Recruiting

Sherbrooke, Quebec J1L 0H8, Canada

Diex Recherche (Trois-Rivieres)Recruiting

Trois-Rivières, Quebec G9A 4P3, Canada

Institut Universitaire de Cardiologie et de Pneumologie de Quebec (IUCPQ)Recruiting

Québec, G1V 4G5, Canada

CIUSSS du Saguenay - Lac-Saint-JeanNot yet recruiting

Québec, G7H 5H6, Canada

Enroll SpaRecruiting

Santiago, 7500587, Chile

CeCim - Centro de Estudios Clinicos e Investigacion MedicaRecruiting

Santiago, 8331143, Chile

Centro de Investigacion del MauleRecruiting

Talca, 3465586, Chile

Hospital Las HiguerasRecruiting

Talcahuano, 4270918, Chile

CECMI LtdaRecruiting

Temuco, 4780000, Chile

CINVEC - Centro de Investigacion Clinica V Reg.,Vina del MarRecruiting

Viña del Mar, 2520997, Chile

Beijing AnZhen Hospital, Capital Medical UniversityRecruiting

Beijing, 100029, China

Cardiovascular Institute and Fu Wai HospitalRecruiting

Beijing, 100037, China

Jilin Province People's HospitalRecruiting

Changchun, 130021, China

The First Hospital of Jilin UniversityRecruiting

Changchun, 130021, China

China-Japan Union Hospital of Jilin UniversityRecruiting

Changchun, 130033, China

Changde Second People's HospitalRecruiting

Changde, 415001, China

Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University)Recruiting

Changsha, 410005, China

The Second Xiangya Hospital Of Central South UniversityRecruiting

Changsha, 410011, China

The Third Hospital of ChangshaRecruiting

Changsha, 410015, China

People's Hospital of Sichuan ProvinceRecruiting

Chengdu, 610072, China

Chenzhou No.1 people's HospitalRecruiting

Chenzhou, 423000, China

Second Affiliated Hospital Chongqing Medical UniversityRecruiting

Chongqing, 400010, China

Chongqing Three Gorges Central HospitalRecruiting

Chongqing, 404000, China

Affiliated Zhongshan Hospital of Dalian UniversityRecruiting

Dalian, 116001, China

Daqingshi People's HospitalRecruiting

Daqing, 163711, China

The First People's Hospital of FoshanRecruiting

Foshan, 528000, China

The First Affiliated Hospital of Fujian Medical UniversityRecruiting

Fuzhou, 350005, China

The First Affiliated Hospital of Guangzhou University of Chinese MedicineRecruiting

Guangzhou, 510000, China

Guangdong Provincial People's HospitalRecruiting

Guangzhou, 510080, China

Third Affiliated Hospital of Guangzhou Medical UniversityRecruiting

Guangzhou, 510150, China

The Affiliated Panyu Central Hospital of Guangzhou Medical UniversityRecruiting

Guangzhou, 511400, China

Guizhou Provincial People's HospitalRecruiting

Guiyang, 550002, China

Hainan General HospitalRecruiting

Haikou, 570311, China

The First Affiliated Hospital of Harbin Medical UniversityRecruiting

Harbin, 150040, China

Jiangmen Central HospitalRecruiting

Jiangmen, 529030, China

Center Hospital of JinanRecruiting

Jinan, 250013, China

Lanzhou University Second HospitalRecruiting

Lanzhou, 730030, China

Linfen Central HospitalRecruiting

Linfen, 041000, China

Luoyang Third People's HospitalRecruiting

Luoyang, 471002, China

The First Affiliated Hospital of Henan University of Science and TechnologyRecruiting

Luoyang, 471003, China

Jiangxi Province Integrated Tractional Chinese Medicine& Western Medicine HospitalRecruiting

Nanchang, 330003, China

The First Affiliated Hospital of Nanchang UniversityRecruiting

Nanchang, 330006, China

Zhongda Hospital Southeast UniversityRecruiting

Nanjing, 210009, China

Nanjing Jiangning HospitalRecruiting

Nanjing, 211100, China

The First Affiliated Hospital of Guangxi Medical UniversityRecruiting

Nanning, 530021, China

Nanyang First People's HospitalRecruiting

Nanyang, 473004, China

Nanyang Second General HospitalRecruiting

Nanyang, 473009, China

Ningbo Second HospitalRecruiting

Ningbo, 315010, China

The First Affiliated Hospital of Ningbo UniversityRecruiting

Ningbo, 315010, China

Pingxiang People's HospitalRecruiting

Pingxiang, 337000, China

Zhongshan Hospital Affiliated to Fudan UniversityRecruiting

Shanghai, 200032, China

Tongren hospital, Shanghai Jiaotong University School of MedicineRecruiting

Shanghai, 200050, China

Shanghai General HospitalRecruiting

Shanghai, 200080, China

Shengjing Hospital of China Medical UniversityRecruiting

Shenyang, 110004, China

People's Hospital of Liaoning ProvinceRecruiting

Shenyang, 110067, China

Shenzhen People's HospitalRecruiting

Shenzhen, 518172, China

The Second Hospital of Hebei Medical UniversityRecruiting

Shijiazhuang, 050000, China

Shanxi Bethune HospitalRecruiting

Taiyuan, 030032, China

Shanxi Cardiovascular HospitalRecruiting

Taiyuan, 30013, China

Taian City Central HospitalRecruiting

Tai’an, 271000, China

Tianjin Union Medical Center Nankai University Affiliated HospitalRecruiting

Tianjin, 300121, China

The 2nd Hospital of Tianjin Medical UniversityRecruiting

Tianjin, 300211, China

Hubei Province Zhongshan HospitalRecruiting

Wuhan, 430032, China

Renmin Hospital of Wuhan UniversityRecruiting

Wuhan, 430060, China

Shaanxi Provincial People's HospitalRecruiting

Xi'an, 710068, China

Xinxiang Central HospitalRecruiting

Xinxiang, 453000, China

The People's Hospital Of Xuancheng CityRecruiting

Xuancheng, 242000, China

The General Hospital of XZCMG (The Second Affiliated Hospital of Xuzhou Medical University)Recruiting

Xuzhou, 221006, China

The first People's Hosptal of YinchuanRecruiting

Yinchuan, 750001, China

Yueyang Central HospitalRecruiting

Yueyang, 414000, China

Yuncheng Central HospitalRecruiting

Yuncheng, 44000, China

The First Affiliated Hospital of Hebei North UniversityRecruiting

Zhangjiakou, 075000, China

The First Affiliated Hospital of Zhengzhou UniversityRecruiting

Zhengzhou, 450008, China

Affiliated Hospital of Jiangsu UniversityRecruiting

Zhenjiang, 212001, China

Cardiomet CEQUIN S.A.SRecruiting

Armenia, 630001, Colombia

Centro de Investigacion Medico Asistencial S.A.SRecruiting

Barranquilla, 80020, Colombia

Corazon IPS S.A.S.Recruiting

Barranquilla, 80020, Colombia

Fundacion Santa Fe de BogotaRecruiting

Bogotá, 110111, Colombia

Administradora Country S.A.S.Recruiting

Bogotá, 110221, Colombia

Fundacion Hospital Infantil Universitario de San JoseRecruiting

Bogotá, 111221, Colombia

IPS Centro Medico Julián Coronel S.A.Recruiting

Cali, 760001, Colombia

Centro de Diagnostico Cardiologico S.A.S.Recruiting

Cartagena, 130001, Colombia

IPS médicos internistas de Caldas S.A.S.Recruiting

Manizales, 170004, Colombia

T Y C Inversiones S.A.S GrupsaludRecruiting

Santa Marta, 470001, Colombia

MUDr. Hana BurianovaRecruiting

Bílovec, 743 01, Czechia

Medicus Services s.r.o.Recruiting

Brandýs nad Labem, 250 01, Czechia

Fakultni nemocnice u sv. Anny v BrneRecruiting

Brno, 602 00, Czechia

MUDr. Jan Hubac s.r.o.Recruiting

Chrudim, 537 01, Czechia

EDUMED s.r.o.Recruiting

Jaroměř, 551 01, Czechia

MUDr Petra Maskova PhDRecruiting

Litovel, 784 01, Czechia

KardioBusak s.r.o.Recruiting

Louny, 440 01, Czechia

InterKardioML s.r.o.Recruiting

Mariánské Lázně, 353 01, Czechia

MUDr. Zdenek Vomacka kardiologie a interna s.r.o.Recruiting

Olomouc, 779 00, Czechia

MUDr. Jan Kvasnicka CScRecruiting

Prague, 10100, Czechia

Kardiologie Vinohrady s r oRecruiting

Prague, 11000, Czechia

Institute for Clinical and Experimental MedicineRecruiting

Prague, 140 21, Czechia

University Thomayer´s HospitalRecruiting

Praha 4-Krc, 140 59, Czechia

Boehringer IngelheimContact

support@bitrialsupport.com00441144040048

Nemocnice SlanyRecruiting

Slaný, 274 01, Czechia

Kardiologicka ambulance MUDr. Ferkl s.r.o.Recruiting

Trutnov, 541 01, Czechia

Clinical Trials Services s.r.oRecruiting

Uherské Hradiště, 68601, Czechia

Sygehus Sønderjylland ÅbenråRecruiting

Aabenraa, 6200, Denmark

Rigshospitalet CopenhagenRecruiting

Copenhagen, 2100, Denmark

Bispebjerg og Frederiksberg HospitalRecruiting

Copenhagen NV, 2400, Denmark

Boehringer IngelheimContact

danmark@bitrialsupport.com80711822

Amager-Hvidovre HospitalRecruiting

Copenhagen S, 2300, Denmark

Boehringer IngelheimContact

danmark@bitrialsupport.com80711822

Herlev and Gentofte HospitalRecruiting

Herlev, 2730, Denmark

Holbæk SygehusRecruiting

Holbæk, 4300, Denmark

Hvidovre HospitalRecruiting

Hvidovre, 2650, Denmark

Sjællands UniversitetshospitalRecruiting

Roskilde, 4000, Denmark

Slagelse SygehusRecruiting

Slagelse, 4200, Denmark

Klinikum am PlattenwaldRecruiting

Bad Friedrichshall, 74177, Germany

Boehringer IngelheimContact

deutschland@bitrialsupport.com08007234742

CIMS Studienzentrum Bamberg GmbHRecruiting

Bamberg, 96049, Germany

Vivantes Netzwerk für Gesundheit GmbHRecruiting

Berlin, 10249, Germany

Velocity Clinical Research Germany GmbH, BerlinRecruiting

Berlin, 10787, Germany

Vivantes Humboldt-KlinikumNot yet recruiting

Berlin, 13509, Germany

GFO Kliniken Bonn, Betriebsstaette St. MarienRecruiting

Bonn, 53115, Germany

Universitätsklinikum Bonn AöRRecruiting

Bonn, 53127, Germany

Internistische Gemeinschaftspraxis in BündeNot yet recruiting

Bünde, 32257, Germany

SANA Kliniken Oberfranken Coburg GmbHNot yet recruiting

Coburg, 96450, Germany

Klinische Forschung Dresden GmbHRecruiting

Dresden, 01069, Germany

Facharztzentrum Dresden-Neustadt Betriebsgesellschaft mbHRecruiting

Dresden, 01099, Germany

Helios Klinikum ErfurtRecruiting

Erfurt, 99089, Germany

Klinische Forschung Hannover-Mitte GmbHRecruiting

Hanover, 30159, Germany

Medizinische Hochschule HannoverRecruiting

Hanover, 30625, Germany

Kardiopraxis SchirmerRecruiting

Kaiserslautern, 67655, Germany

Universitätsklinikum Schleswig-Holstein, Campus KielRecruiting

Kiel, 24105, Germany

Asklepios Klinik Langen-Seligenstadt GmbHRecruiting

Langen, 63225, Germany

Velocity Clinical Research Germany GmbH, LeipzigRecruiting

Leipzig, 04177, Germany

Klinikum der Stadt Ludwigshafen am Rhein GmbHRecruiting

Ludwigshafen, 67063, Germany

Praxis OedemeRecruiting

Lüneburg, 21339, Germany

ze:ro Praxen MVZ fuer Nierenerkrankungen und Bluthochdruck GmbH MannheimRecruiting

Mannheim, 68165, Germany

Marienhaus Klinikum St. ElisabethRecruiting

Neuwied, 56564, Germany

Kardiologische Praxis PapenburgRecruiting

Papenburg, 26871, Germany

Universitätsklinikum RegensburgRecruiting

Regensburg, 93053, Germany

Gemeinschaftspraxis Dr. Josef Grosskopf und Dr. Wilma GrosskopfRecruiting

Wallerfing, 94574, Germany

Cardiologicum Hamburg GbRRecruiting

Wandsbek, 22041, Germany

Kardiologische Praxis, WermsdorfRecruiting

Wermsdorf, 04779, Germany

Velocity Clinical Research Germany GmbH, WiesbadenRecruiting

Wiesbaden, 65189, Germany

Klinikum Worms gGmbHRecruiting

Worms, 67550, Germany

Belgyogyaszati es Kardiologiai MaganrendeloRecruiting

Békéscsaba, 5600, Hungary

Betegapolo Irgalmasrend Budai Irgalmasrendi KorhazRecruiting

Budapest, 1023, Hungary

Obudai Egeszegugyi CentrumRecruiting

Budapest, 1036, Hungary

Belvaros-Lipotvaros Egeszsegugyi SzolgalatRecruiting

Budapest, 1051, Hungary

Gottsegen National Cardiovascular CenterRecruiting

Budapest, 1096, Hungary

Semmelweis UniversityRecruiting

Budapest, 1122, Hungary

Privat Doktor Egeszseguegyi Szolgaltato Zrt.Recruiting

Budapest, 1132, Hungary

Kardio Innova Kft.Recruiting

Budapest, 1134, Hungary

BKS Research LtdRecruiting

Hatvan, 3000, Hungary

Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato KorhazRecruiting

Miskolc, 3526, Hungary

IPR Hungary Kft.Recruiting

Miskolc, 3530, Hungary

TaNa Med Kft.Recruiting

Mosonmagyaróvár, 9200, Hungary

Coromed-Smo Kft.Recruiting

Pécs, 7623, Hungary

Tolna Varmegyei Balassa Janos KorhazRecruiting

Szekszárd, 7100, Hungary

Belvarosi Egeszseghaz Kft.Recruiting

Zalaegerszeg, 8900, Hungary

Kamal Nayan Bajaj HospitalRecruiting

Aurangabad, 431005, India

Narayana Institute of Cardiac SciencesRecruiting

Bangalore, 560099, India

S.P. Medical College & Associated Group of HospitalsRecruiting

Bikaner, 334003, India

Tamil Nadu Government Multi Super Speciality Hospital TNGMSSHRecruiting

Chennai, 600002, India

Apollo Hospital - ChennaiRecruiting

Chennai, 600006, India

Lisie HospitalRecruiting

Kochi, 682 018, India

IPGMER and SSKM HospitalRecruiting

Kolkata, 700020, India

Supe Heart & Diabetes Hospital & Research CentreRecruiting

Nashik, 422002, India

Chopda Medicare and Research Centre Pvt LtdRecruiting

Nashik, 422005, India

Max Super Speciality HospitalRecruiting

New Delhi, 110017, India

Indira Gandhi Institute of Medical SciencesRecruiting

Patna, 800014, India

Nirmal HospitalRecruiting

Surat, 395002, India

Unicare Heart InstituteRecruiting

Surat, 395002, India

King George HospitalRecruiting

Visakhapatnam, 530002, India

Humanitas GavazzeniRecruiting

Bergamo, 24125, Italy

ASST Papa Giovanni XXIIIRecruiting

Bergamo, 24127, Italy

Azienda Ospedaliera Universitaria "Federico II"Recruiting

Naples, 80131, Italy

Fondazione IRCCS Policlinico S. MatteoRecruiting

Pavia, 27100, Italy

Azienda Ospedaliera Universitaria PisanaRecruiting

Pisa, 56126, Italy

Azienda Ospedaliera Sant'Andrea-Università di Roma La SapienzaRecruiting

Roma, 00189, Italy

Istituto Clinico HumanitasRecruiting

Rozzano, 20089, Italy

Hyogo Prefectural Amagasaki General Medical CenterRecruiting

Amagasaki-shi, 660-8550, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Asahi General HospitalRecruiting

Asahi-shi, 289-2511, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Shonan Fujisawa Tokushukai HospitalRecruiting

Fujisawa-shi, 251-0041, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Kyushu University HospitalRecruiting

Fukuoka, 812-8582, Japan

Fukuokaken Saiseikai Futsukaichi HospitalRecruiting

Fukuoka, Chikushino, 818-8516, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Gunma University HospitalRecruiting

Gunma, Maebashi, 371-8511, Japan

Minamino Cardiovascular HospitalRecruiting

Hachioji-shi, 192-0918, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

National Hospital Organization Hamada Medical CenterRecruiting

Hamada-shi, 697-8511, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

JA-Shizuoka Enshu HospitalRecruiting

Hamamatsu, 430-0929, Japan

Hyogo Prefectural Harima-Himeji General Medical CenterRecruiting

Himeji-shi, 670-8560, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Hiratsuka Kyosai HospitalRecruiting

Hiratsuka-shi, 254-8502, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Hitachi Ltd. Hitachinaka General HospitalRecruiting

Hitachi-Naka, 312-0057, Japan

National Hospital Organization Kanazawa Medical CenterRecruiting

Ishikawa, Kanazawa, 920-8650, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

National Hospital Organization Iwakuni Clinical CenterRecruiting

Iwakuni-shi, 740-8510, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Tokushukai Shonan Kamakura General HospitalRecruiting

Kamakura-shi, 247-8533, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Tokushukai Hayama Heart CenterRecruiting

Kanagawa, Miura-gun, 240-0116, Japan

Mitoyo General HospitalRecruiting

Kanonji-shi, 769-1695, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Ibaraki Prefectural Central HospitalRecruiting

Kasama-shi, 309-1793, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Kasugai Municipal HospitalRecruiting

Kasugai-shi, 486-8510, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Saiseikai Kawaguchi HospitalRecruiting

Kawaguchi-shi, 332-8558, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

St. Marianna University HospitalRecruiting

Kawasaki-shi, 216-8511, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Tokushukai Kishiwada Tokushukai HospitalRecruiting

Kishiwada-shi, 596-0042, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

National Hospital Organization Kobe Medical CenterRecruiting

Kobe, 654-0155, Japan

Kumamoto University HospitalRecruiting

Kumamoto, 860-8556, Japan

Japanese Red Cross Kumamoto HospitalRecruiting

Kumamoto, 861-8520, Japan

National Hospital Organization Kure Medical Center and Chugoku Cancer CenterRecruiting

Kure, 737-0023, Japan

Chibanishi General HospitalRecruiting

Matsudo-shi, 270-2251, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Shinshu University HospitalRecruiting

Matsumoto-shi, 390-8621, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Ehime Prefectural Central HospitalRecruiting

Matsuyama, 790-0024, Japan

Matsuyama Shimin HospitalRecruiting

Matsuyama, 790-0067, Japan

National Hospital Organization Tokyo Medical CenterRecruiting

Meguro-ku, 152-8902, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Mito Saiseikai General HospitalRecruiting

Mito, 311-4198, Japan

Sendai Cardiovascular CenterRecruiting

Miyagi, Sendai, 981-3133, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Nagasaki Harbor Medical CenterRecruiting

Nagasaki, Nagasaki, 850-8555, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Nagoya Kyoritsu HospitalRecruiting

Nagoya, 454-0933, Japan

Nagoya City University HospitalRecruiting

Nagoya, 467-8602, Japan

Hokushin General HospitalRecruiting

Nakano-shi, 383-8505, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Nara Medical University HospitalRecruiting

Nara, Kashihara, 634-8522, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Juzenkai The Sakakibara Heart Institute of OkayamaRecruiting

Okayama, Okayama, 700-0804, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Ome Municipal General HospitalRecruiting

Ome-shi, 198-0042, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Nagasaki Medical CenterRecruiting

Omura-shi, 856-8562, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Osaka Metropolitan University HospitalRecruiting

Osaka, 545-8586, Japan

Osaka General Medical CenterRecruiting

Osaka, 558-8558, Japan

Kosekai Iwatsuki-minami HospitalRecruiting

Saitama, Saitama, 339-0033, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Osaka Rosai HospitalRecruiting

Sakaishi, 591-8025, Japan

Teine Keijinkai HospitalRecruiting

Sapporo, 006-8555, Japan

Tohoku University HospitalRecruiting

Sendai, 980-8547, Japan

NHO Sendai Medical CenterRecruiting

Sendai, 983-8520, Japan

NHO Kanmon Medical CenterRecruiting

Shimonoseki-shi, 752-8510, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

National Cerebral and Cardiovascular CenterRecruiting

Suita-shi, 564-8565, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

The University of Osaka HospitalRecruiting

Suita-shi, 565-0871, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Tachikawa HospitalRecruiting

Tachikawa-shi, 190-8531, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

National Hospital Organization Takasaki General Medical CenterRecruiting

Takasaki-shi, 370-0829, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

NHO Minami Wakayama Medical CenterRecruiting

Tanabe-shi, 646-8558, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Tokushima Prefectural Central HospitalRecruiting

Tokushima, 770-8539, Japan

Tomakomai City HospitalRecruiting

Tomakomai-shi, 053-8567, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Toyota Memorial HospitalRecruiting

Toyota-shi, 471-8513, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

NHO Shinshu Ueda Medical CenterRecruiting

Ueda-shi, 386-8610, Japan

Boehringer IngelheimContact

nippon@bitrialsupport.com05050508862

Hospital Cardiologica AguascalientesRecruiting

Aguascalientes, 20230, Mexico

Centro Especializado de Investigación Medical Group CuliacanNot yet recruiting

Culiacán, 80200, Mexico

Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada S.C.Not yet recruiting

Culiacán, 80230, Mexico

Cardiologia Clinica e IntervencionistaRecruiting

Guadalajara, 44670, Mexico

Proactive CR Mexico S.A. de C.V.Not yet recruiting

Irapuato, 36520, Mexico

Clinstile S.A. de C.V.Not yet recruiting

México, 06700, Mexico

Cardiolink Clin Trials S.C.Not yet recruiting

Monterrey, 64060, Mexico

Hospital Universitario Dr Jose Eleuterio GonzalezRecruiting

Monterrey, 64460, Mexico

Centro de Estudios Clinicos de Queretaro S.CRecruiting

Querétaro, 76000, Mexico

Centro de Investigacion Cardiovascular y MetabolicaNot yet recruiting

Tijuana, 22500, Mexico

CIMAB S.A. de C.V.Recruiting

Torreón, 27000, Mexico

Universitair Medisch Centrum GroningenRecruiting

Groningen, 9713 GZ, Netherlands

Maastricht University Medisch CentrumRecruiting

Maastricht, 6229 HX, Netherlands

St. Antonius ZiekenhuisRecruiting

Nieuwegein, 3435 CM, Netherlands

Isala Klinieken StichtingRecruiting

Zwolle, 8025 AB, Netherlands

Polsko-Amerykanskie Kliniki SercaRecruiting

Bielsko-Biala, 43-316, Poland

Centrum Medyczne Intercor Sp. z o.o.Recruiting

Bydgoszcz, 85-092, Poland

Pratia Bydgoszcz Clinical Research SiteRecruiting

Bydgoszcz, 85-796, Poland

NZOZ Medical Center KERmedRecruiting

Bydgoszcz, 85231, Poland

Centrum Medyczne Pratia GdyniaRecruiting

Gdynia, 81-338, Poland

Specjalistyczna Praktyka Lekarska Ewa Mirek-BryniarskaRecruiting

Krakow, 30-082, Poland

Pratia MCM KrakowRecruiting

Krakow, 30-727, Poland

Beata Miklaszewicz & Dariusz Dabrowski Cardiamed Sp. j.Recruiting

Legnica, 59-220, Poland

Santa SP. z o.oRecruiting

Lodz, 90-302, Poland

Velocity Nova Sp. z o.o.Recruiting

Lublin, 20-362, Poland

Zanamed Medical Clinic Sp. z o.o.Recruiting

Lublin, 20-601, Poland

Nzoz HeurekaRecruiting

Piaseczno, 05-500, Poland

CBK Med Clinic SP Z O ORecruiting

Płock, 09-407, Poland

Centrum Medyczne MedykRecruiting

Rzeszów, 35-055, Poland

Lukmed Lukasz WozniakRecruiting

Siedlce, 08-110, Poland

Velocity Skierniewice Sp. z o.oRecruiting

Skierniewice, 96-100, Poland

Centrum Medyczne Pratia PoznanRecruiting

Skórzewo, 60-185, Poland

Velocity StaszowRecruiting

Staszów, 28-200, Poland

Sedimed Sp. z o.o.Recruiting

Szczecin, 70-240, Poland

Balsammedica Sp. z o. o.Recruiting

Warsaw, 01249, Poland

MTZ Clinical Research Powered by PratiaRecruiting

Warsaw, 02-172, Poland

ETG WarszawaRecruiting

Warsaw, 02-677, Poland

4. Military Clinical Hospital with Polyclinic SP ZOZRecruiting

Wroclaw, 50-981, Poland

Sedimed Sp. z o.o.Recruiting

Wroclaw, 53-030, Poland

Velocity Nova Sp. z o.o.Recruiting

Zamość, 22-400, Poland

Centrum Medyczne Serafin medRecruiting

Żarów, 58-130, Poland

Spitalul Judetean De Urgenta Dr. Constantin Opris Baia MareRecruiting

Baia Mare, 430031, Romania

Spitalul Clinic De Urgenta Prof Dr Agrippa IonescuRecruiting

Baloteşti, 77015, Romania

S.C.Centrul Medical Unirea S.R.L.Recruiting

Brasov, 500091, Romania

Spitalul Clinic Judetean de Urgenta BrasovRecruiting

Brasov, 500365, Romania

Emergency University HospitalRecruiting

Bucharest, 050098, Romania

Clinica Medicala Data Plus SRLRecruiting

Bucharest, 10192, Romania

Spitalul Angiocare SRLRecruiting

Cluj-Napoca, 400015, Romania

Emergency County Hospital CraiovaRecruiting

Craiova, 200640, Romania

Spitalul Clinic Judetean de Urgenta BihorRecruiting

Oradea, 410167, Romania

Sal Med SrlRecruiting

Piteşti, 110424, Romania

U 2 Serv Com S.R.L.Recruiting

Suceava, 720049, Romania

Country Clinical Emergency Hospital, Targu-MuresRecruiting

Târgu Mureş, 540136, Romania

Podoleanu G. Cristian-Gheorghe-CalinRecruiting

Târgu Mureş, 540143, Romania

Spitalul Clinic Judetean de Urgenta Targu MuresRecruiting

Târgu Mureş, 54136, Romania

S.C Medicali's S.R.LRecruiting

Timișoara, 300043, Romania

Timisoara Municipal Emergency Clinical HospitalRecruiting

Timișoara, 300079, Romania

King AbdulAziz University HospitalRecruiting

Al Ahsa, Saudi Arabia

Boehringer IngelheimContact

saudi@bitrialsupport.com8001263002

King Fahad Specialist Hospital - Research CenterRecruiting

Dammam, 31444, Saudi Arabia

Imam Abdulrahman bin Faisal UniversityRecruiting

Dammam, 34212, Saudi Arabia

King Faisal Specialist Hospital and Research CenterRecruiting

Riyadh, 11211, Saudi Arabia

Clinical Center " Dr Dragisa Misovic Dedinje"Recruiting

Belgrade, 11000, Serbia

University Clinical Center of SerbiaRecruiting

Belgrade, 11000, Serbia

University Clinical Center of KragujevacRecruiting

Kragujevac, 34000, Serbia

University Clinical Center NisRecruiting

Niš, 18000, Serbia

Institute for Treatment and Rehabilitation, Niska BanjaRecruiting

Niška Banja, 18205, Serbia

General Hospital PancevoRecruiting

Pančevo, 26000, Serbia

General Hospital Sveti LukaRecruiting

Smederevo, 11300, Serbia

Institute of Cardiovascular Diseases of VojvodineRecruiting

Sremska Mitrovica, 21204, Serbia

Health Centre ZajecarRecruiting

Zaječar, 19000, Serbia

Stredoslovensky Ustav Srdcovych A Cievnych Chorob A SRecruiting

Banská Bystrica, 974 01, Slovakia

Alian s.r.o.Recruiting

Bardejov, 08501, Slovakia

Cliniq s.r.o.Recruiting

Bratislava, 81109, Slovakia

Premedix ClinicRecruiting

Bratislava, 83101, Slovakia

Nemocnica S Poliklinikou Brezno N.O.Recruiting

Brezno, 977 01, Slovakia

Medical Group Kosice s.r.oRecruiting

Košice, 04001, Slovakia

KARDIO R s r oRecruiting

Košice, 04011, Slovakia

Cardio D&R s.r.o. KosiceRecruiting

Košice, 04022, Slovakia

KARDIO 1 s.r.o.Recruiting

Lučenec, 984 01, Slovakia

Kardiomed s.r.o.Recruiting

Lučenec, 98401, Slovakia

KVC Kardiovaskularne Centrum s.r.o.Recruiting

Martin, 036 01, Slovakia

Cardioamb s.r.oRecruiting

Nové Zámky, 94002, Slovakia

Nemocnica AGEL Zvolen a.s.Recruiting

Zvolen, 960 01, Slovakia

Inje University Busan Paik HospitalRecruiting

Busan, 47392, South Korea

Dong-A University HospitalRecruiting

Busan, 49201, South Korea

Pusan National University Yangsan HospitalRecruiting

Busan, 49241, South Korea

Chonnam National University HospitalRecruiting

Gwangju, 61469, South Korea

Gachon University Gil Medical CenterRecruiting

Incheon, 21565, South Korea

Seoul National University Bundang HospitalRecruiting

Seongnam, 13620, South Korea

Severance HospitalRecruiting

Seoul, 03722, South Korea

Samsung Medical CenterRecruiting

Seoul, 06351, South Korea

Korea University Guro HospitalRecruiting

Seoul, 08308, South Korea

Korea University Anam HospitalRecruiting

Seoul, 2841, South Korea

Yonsei University Wonju Severance Christian HospitalRecruiting

Wŏnju, 26426, South Korea

Hospital Clínic de BarcelonaRecruiting

Barcelona, 08036, Spain

Hospital Universitario 12 de OctubreRecruiting

Madrid, 28041, Spain

Hospital Universitario La PazRecruiting

Madrid, 28046, Spain

Hospital Virgen del CaminoRecruiting

Sanlúcar de Barrameda, 11540, Spain

Hospital Universitario De TorrejonRecruiting

Torrejón de Ardoz, 28850, Spain

Hospital Clinico Universitario de ValenciaRecruiting

Valencia, 46010, Spain

Hospital General Universitario de ValenciaRecruiting

Valencia, 46014, Spain

Hospital Universitari i Politècnic La FeRecruiting

Valencia, 46026, Spain

Hospital Virgen de las MontañasRecruiting

Villamartín, 11650, Spain

Kaohsiung Medical University Chung-Ho Memorial HospitalRecruiting

Kaohsiung City, 807, Taiwan

E-Da HospitalRecruiting

Kaohsiung City, 82445, Taiwan

China Medical University HospitalRecruiting

Taichung, 40447, Taiwan

Taichung Veterans General HospitalRecruiting

Taichung, 407219, Taiwan

Taipei Medical University HospitalRecruiting

Taipei, 110, Taiwan

Taipei Veterans General HospitalRecruiting

Taipei, 11217, Taiwan

Tri-Service General HospitalRecruiting

Taipei, 114202, Taiwan

Changhua Christian HospitalRecruiting

Taipei, 50006, Taiwan

Cukurova Universitesi Tip Fakultesi Gog. Hast. Anabilim DaliRecruiting

Adana, 01330, Turkey (Türkiye)

Ataturk Universitesi Tip FakultesiRecruiting

Erzurum, 25240, Turkey (Türkiye)

Osmangazi Uni Medical FacultyRecruiting

Eskişehir, 26480, Turkey (Türkiye)

Gaziantep University Medical Faculty Sahinbey Educational Research HospitalRecruiting

Gaziantep, 27310, Turkey (Türkiye)

Siyami Ersek Heart HospitalNot yet recruiting

Istanbul, 34668, Turkey (Türkiye)

Kutahya Health Science UniversityRecruiting

Kütahya, 43040, Turkey (Türkiye)

Inonu Uni. Med. Fac., BattalgaziRecruiting

Malatya, 44280, Turkey (Türkiye)

Mersin University Medical FacultyRecruiting

Mersin, 33020, Turkey (Türkiye)

Southmead HospitalRecruiting

Bristol, BS10 5NB, United Kingdom

Golden Jubilee National HospitalRecruiting

Clydebank, G81 4DY, United Kingdom

Royal Devon and Exeter Hospital, WonfordRecruiting

Exeter, EX2 5DW, United Kingdom

Calderdale Royal HospitalRecruiting

Halifax, HX3 0PW, United Kingdom

Northwick Park HospitalRecruiting

Harrow, HA1 3UJ, United Kingdom

St Bartholomew's HospitalRecruiting

London, EC1A 7BE, United Kingdom

Bach Mai hospitalNot yet recruiting

Hanoi, 100000, Vietnam

Tam Anh General HospitalRecruiting

Hanoi, 100000, Vietnam

Hanoi Heart HospitalRecruiting

Hà Nội, 150000, Vietnam

Military Hospital 175Not yet recruiting

Ho Chi Minh City, 700000, Vietnam

Nguyen Tri Phuong HospitalNot yet recruiting

Ho Chi Minh City, 700000, Vietnam

Tam Anh HCMCRecruiting

Ho Chi Minh City, 700000, Vietnam

Thong Nhat Hospital HCMCRecruiting

Ho Chi Minh City, 700000, Vietnam

Cho Ray HospitalRecruiting

Ho Chi Minh City, 70000, Vietnam

University Medical Center HCMCRecruiting

Ho Chi Minh City, 70000, Vietnam

Trung Vuong HospitalRecruiting

Ho Chi Minh City, Vietnam