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For patients diagnosed with early gastric cancer involving submucosal invasion, super-ESD indications, or lymph node metastasis, a combination of preoperative endoscopic ultrasound and abdominal contrast-enhanced CT was utilized to ascertain the depth of tumor invasion and to identify any suspicious metastatic lymph nodes in the vicinity of the stomach. Subsequently, a local full-thickness resection, coupled with or followed by individualized precise lymph node dissection, was conducted to fulfill the following objectives: â‘ To investigate the safety, feasibility, and efficacy of local resection for patients meeting super-ESD criteria; â‘¡ To offer a clinical foundation for the individualized and precise lymph node dissection treatment of early gastric cancer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | Experimental | Patients in group A-No lymph node metastasis, who underwent simple Double-Endoscopic Combined with local full-thickness resection. |
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| Group B | Experimental | Patients in group B-imaging examination showed lymph node metastasis. patients were randomly divided into Group N + a and Group N + b. Group N + a: Local full-thickness gastric wall and lymph nodes dissection on D1 or D1 + were performed with Double-Endoscopic Group N + b: Traditional standard surgical gastrectomy and D1 or D1 + lymph nodes dissection was performed . |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sixty patients with early gastric cancer in stage T1bN0-1M0 were divided into Group A-N0 and Group B-N + according to the presence or absence of lymph node metastasis. When the enrolled patients und | Procedure | Patients in group A-No lymph node metastasis, who underwent simple Double-Endoscopic Combined with local full-thickness resection. Patients in group B-imaging examination showed lymph node metastasis. patients were randomly divided into Group N + a and Group N + b. Group N + a: Local full-thickness gastric wall and lymph nodes dissection on D1 or D1 + were performed with Double-Endoscopic Group N + b: Traditional standard surgical gastrectomy and D1 or D1 + lymph nodes dissection was performed . |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of recurrence | Within 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| The operation time, complications and hospital stay were recorded | 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Qun Zhao, Ph.D | Contact | China+8613930162111 | zhaoqun@hebmu.edu.cn | |
| Gang pei Yang, Master's degree | Contact | China+8613731153070 |
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