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This prospective study aimed to predict morbidity and mortality after thoracic trauma in intensive care unit evaluated clinical and biochemical data of 50 intensive care unit patients. The research examined demographic factors such as gender, age, and smoking status, trauma scoring systems like ISS and RTS as well as biomarkers such as Surfactant-d and oxygenation parameters including the ROX index, PaOâ‚‚/FiOâ‚‚ ratio and FiOâ‚‚.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| thorax trauma patients | thorax trauma patients admitted to icu |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blood sampling | Diagnostic Test | blood samples obtained for 3 different days, limited to 5cc |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mortality Prediction Using ROX Index in Thoracic Trauma Patients | To evaluate the predictive ability of the ROX index (unit: cmHâ‚‚O/L/s) for mortality in thoracic trauma patients. ROX index values were recorded at 1st, 3rd, and 7th days of hospitalization using standard clinical monitoring and ventilatory support parameters. Trends were analyzed in relation to survival outcomes. | Measurements taken on day 1, day 3, and day 7 of hospitalization, following ICU admission. |
| Mortality Prediction Using SP-D Levels in Thoracic Trauma Patients | To assess the prognostic value of Surfactant Protein D (SP-D) levels (unit: ng/mL) for mortality prediction in thoracic trauma patients. SP-D levels were measured using an ELISA assay (Elabscience® Human Pulmonary Surfactant-associated Protein-D ELISA Kit) at 1st, 3rd, and 7th days to evaluate trends and correlations with survival outcomes. | Measurements taken on day 1, day 3, and day 7 of hospitalization, following ICU admission. |
| Measure | Description | Time Frame |
|---|---|---|
| Predictive Value of APACHE II Score in Mortality | To analyze the effectiveness of the APACHE II score (range: 0-71; higher scores indicate worse outcomes) in predicting mortality in thoracic trauma patients. APACHE II scores were calculated based on clinical and laboratory parameters, including vital signs, blood gas values, and organ dysfunction markers at 1st, 3rd, and 7th days. | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
| Measure | Description | Time Frame |
|---|---|---|
| NEU/LYM Ratio and Mortality Correlation | To investigate the prognostic role of the Neutrophil-to-Lymphocyte Ratio (NEU/LYM) (unit: ratio value) in predicting mortality among thoracic trauma patients. NEU/LYM values were obtained from complete blood count (CBC) results and recorded at 1st, 3rd, and 7th days | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
Inclusion Criteria:
Exclusion Criteria:
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Patients with thoracic trauma admitted to icu
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| Name | Affiliation | Role |
|---|---|---|
| pınar karabacak | Suleyman Demirel University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Suleyman Demirel University | Isparta | 32260 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20158912 | Background | Determann RM, Royakkers AA, Haitsma JJ, Zhang H, Slutsky AS, Ranieri VM, Schultz MJ. Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients. BMC Pulm Med. 2010 Feb 16;10:6. doi: 10.1186/1471-2466-10-6. | |
| 32507628 | Background | Baker JE, Millar DA, Heh V, Goodman MD, Pritts TA, Janowak CF. Does chest wall Organ Injury Scale (OIS) or Abbreviated Injury Scale (AIS) predict outcomes? An analysis of 16,000 consecutive rib fractures. Surgery. 2020 Jul;168(1):198-204. doi: 10.1016/j.surg.2020.04.032. Epub 2020 May 13. |
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Hemogram Biochemical markers arterial blood gas analyses
| Predictive Value of SOFA Score in Mortality | To evaluate the prognostic accuracy of the Sequential Organ Failure Assessment (SOFA) score (range: 0-24; higher scores indicate worse outcomes) in thoracic trauma patients. SOFA scores were determined based on respiratory, cardiovascular, hepatic, coagulation, renal, and neurological functions at 1st, 3rd, and 7th days. | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
| Predictive Value of TRISS Score in Mortality | To examine the relationship between Trauma and Injury Severity Score (TRISS) (range: 0-100%; higher scores indicate better survival probability) and survival outcomes in thoracic trauma patients. TRISS scores were calculated using physiological and anatomical injury severity data at 1st, 3rd, and 7th days. | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
| Predictive Value of RTS Score in Mortality | To assess the relationship between Revised Trauma Score (RTS) (range: 0-7.84; higher scores indicate better prognosis) and mortality risk in thoracic trauma patients. RTS scores were calculated using Glasgow Coma Scale, systolic blood pressure, and respiratory rate values at 1st, 3rd, and 7th days. | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
| CRP Levels and Mortality Prediction | To evaluate the association between C-reactive protein (CRP) levels (unit: mg/L) and mortality in thoracic trauma patients. | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
| Procalcitonin Levels and Mortality Prediction | To analyze the prognostic value of procalcitonin (unit: ng/mL) levels in mortality prediction among thoracic trauma patients. | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
| Glasgow Coma Scale (GCS) and Mortality Correlation | Description: To evaluate the predictive value of the Glasgow Coma Scale (GCS) score on mortality and other clinical outcomes in thoracic trauma patients. Score Range: 3-15 (lower scores indicate worse outcomes). | Measurements taken on day 1, day 3, and day 7 of hospitalization. |
| 36503613 | Background | Lundin A, Akram SK, Berg L, Goransson KE, Enocson A. Thoracic injuries in trauma patients: epidemiology and its influence on mortality. Scand J Trauma Resusc Emerg Med. 2022 Dec 12;30(1):69. doi: 10.1186/s13049-022-01058-6. |
| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |
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