Normal Pediatric Liver and Spleen SWE

Normal Liver and Spleen Stiffness Values Using Shear Wave Elastography in Children

This observational study aims to determine normal liver and spleen stiffness values in healthy children using shear wave elastography (SWE). The study will include participants from the pediatric age group without known liver or spleen disease. SWE measurements will be performed non-invasively to establish reference values. The results may contribute to improving diagnostic accuracy in pediatric elastography applications.

Shear wave elastography (SWE) is a non-invasive imaging method used to assess tissue stiffness. While reference values for SWE have been established in adults, data regarding normal liver and spleen stiffness in children are limited. This single-center, cross-sectional observational study aims to establish normative SWE values for the liver and spleen in the pediatric age group. Children with no known liver or spleen pathology will undergo standardized SWE measurement under controlled conditions. Age-specific and sex-specific reference ranges will be analyzed, which may contribute to enhancing the clinical utility of SWE in pediatric practice.

Inclusion Criteria:

• Healthy children aged 0-18 years
• No known liver or spleen pathology
• Written informed consent obtained from parents or guardians

Exclusion Criteria:

• Known liver disease (e.g., hepatitis, cirrhosis)
• Known spleen disease (e.g., splenomegaly)
• Any history of liver or spleen disease
• Age outside the 0-18 years range