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The goal of this observational study is to develop and validate a predictive model for prolonged mechanical ventilation (PMV) following acute type A aortic dissection (ATAAD) surgery.
The main questions it aims to answer are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Development cohort | As the development cohort, this cohort retrospectively enrolled approximately 1000 postoperative patients undergoing acute type A aortic dissection (ATAAD) surgery to establish a clinical model for predicting the risk of prolonged mechanical ventilation (PMV) after ATAAD surgery.This cohort will also be utilized to analyze the risk factors for PMV following ATAAD surgery and their impact on clinical outcomes. | ||
| Validation cohort | As the validation cohort, this cohort retrospectively enrolled approximately 400 patients (from January 2024 to December 2024) who underwent ATAAD surgery to validate the predictive performance of the model. |
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| Measure | Description | Time Frame |
|---|---|---|
| The predictive performance of the model for prolonged mechanical ventilation (PMV) following acute type A aortic dissection (ATAAD) surgery | The predictive performance of PMV following ATAAD surgery includes its discriminative ability and calibration ablility. | 72 hours after ATAAD surgery |
| The proportion of patients with PMV | The proportion of patients with PMV refers to the proportion of patients with PMV among the total included ATAAD postoperative patients. PMV is defined as postoperative mechanical ventilation lasting more than 72 hours | 72 hours after ATAAD surgery |
| Measure | Description | Time Frame |
|---|---|---|
| ICU length of stay (ICU-LOS) | ICU length of stay was defined as the length of time spent in ICU from surgery to discharge or death. | From surgery to discharge or death, whichever came first, assessed up to 6 months |
| surgery-related mortality |
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Inclusion Criteria:
Exclusion Criteria:
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ATAAD postoperative patients admitted to SICU
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhou Xiaoming, Dr | Contact | 010-68314466 | zhouxmcmu@163.com | |
| Zhang Qin, Dr | Contact | +86 18990236167 | zhangqincmu@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai Hospital | Beijing | Beijing Municipality | 100029 | China |
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surgery-related mortality encompassed any death occurring during the index hospitalization (even beyond 30 days) or after discharge but before postoperative day 30.
| 30 days after ATAAD surgery |