A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001) | NCT06925737 | Trialant

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001) | NCT06925737 | Trialant

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: Male
Accepts Healthy Volunteers: No
Eligibility Criteria: Inclusion Criteria:

The main inclusion criteria include but are not limited to the following:

Has histologically- or cytologically-confirmed adenocarcinoma of the prostate without small cell histology

Has prostate cancer progression while on androgen deprivation therapy (ADT) (or post bilateral orchiectomy) within 6 months prior to Screening

Has current evidence of distant metastatic disease (M1 disease) documented by either bone lesions on bone scan and/or soft tissue disease by computed tomography (CT)/magnetic resonance imaging (MRI)

Has received prior treatment with 1 or 2 androgen receptor pathway inhibitors (ARPIs) and progressed during or after at least 8 weeks of treatment

Has provided tumor tissue from a core or excisional biopsy from soft tissue not previously irradiated and obtained after disease progression on the most recent prior therapy

Has recovered from adverse events (AEs) due to previous anticancer therapies

Exclusion Criteria:

The main exclusion criteria include but are not limited to the following:

Is unable to swallow tablets/capsules

Has any of the following indicators of interstitial lung disease (ILD)/pneumonitis:

Has any history of ILD/pneumonitis that required steroid use, except for a history of radiation pneumonitis that did not require steroids

Has current ILD/pneumonitis

Has a clinical or radiographic suspicion of ILD for which the diagnosis of ILD cannot be ruled out

Has clinically severe pulmonary compromise resulting from intercurrent pulmonary illnesses

Has uncontrolled or significant cardiovascular disease

Has received prior treatment with a taxane-based chemotherapy agent for metastatic castration-resistant prostate cancer (mCRPC)

Has had prior discontinuation of an antibody drug conjugate (ADC) that consists of an exatecan derivative (eg, trastuzumab deruxtecan) due to treatment-related toxicities

Has a "superscan" bone scan

Mayo Clinic in Arizona - Phoenix ( Site 0044)Recruiting

Phoenix, Arizona 85054, United States

Study CoordinatorContact

855-776-0015

City of Hope Comprehensive Cancer Center ( Site 0049)Recruiting

Duarte, California 91010, United States

City of Hope Lennar Foundation Cancer Center ( Site 0059)Recruiting

Irvine, California 92618, United States

Moores Cancer Center ( Site 0010)Recruiting

La Jolla, California 92093, United States

Veterans Affairs Long Beach Healthcare System ( Site 0058)Recruiting

Long Beach, California 90822, United States

Cedars-Sinai Medical Center ( Site 0068)Recruiting

Los Angeles, California 90048, United States

UCLA Hematology/Oncology - Santa Monica ( Site 0002)Recruiting

Los Angeles, California 90404, United States

University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0006)Recruiting

Orange, California 92868, United States

Stanford Cancer Center ( Site 0046)Recruiting

Palo Alto, California 94304, United States

Rocky Mountain Regional Veterans Affairs Medical Center ( Site 0053)Recruiting

Aurora, Colorado 80045, United States

Yale-New Haven Hospital-Yale Cancer Center ( Site 0050)Recruiting

New Haven, Connecticut 06510, United States

Veterans Affairs Connecticut Healthcare System ( Site 0062)Recruiting

West Haven, Connecticut 06516, United States

The GW Medical Faculty Associates ( Site 0057)Recruiting

Washington D.C., District of Columbia 20037, United States

Washington DC Veterans Affairs Medical Center ( Site 0056)Recruiting

Washington D.C., District of Columbia 20422, United States

Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0077)Recruiting

Jacksonville, Florida 32224, United States

Emory University School of Medicine- Grady Campus ( Site 0103)Recruiting

Atlanta, Georgia 30303, United States

Winship Cancer Institute, Emory University ( Site 0003)Recruiting

Atlanta, Georgia 30322, United States

Rush University Medical Center-Hematology and Oncology ( Site 0028)Recruiting

Chicago, Illinois 60607, United States

University of Illinois at Chicago-University of Illinois Cancer Center ( Site 0063)Recruiting

Chicago, Illinois 60612, United States

University of Kentucky Chandler Medical Center ( Site 0048)Recruiting

Lexington, Kentucky 40536, United States

Greenebaum Comprehensive Cancer Center ( Site 0021)Recruiting

Baltimore, Maryland 21201, United States

Beth Israel Deaconess Medical Center ( Site 0043)Recruiting

Boston, Massachusetts 02215, United States

Dana Farber Cancer Institute ( Site 0012)Recruiting

Boston, Massachusetts 02215, United States

University of Michigan ( Site 0005)Recruiting

Ann Arbor, Michigan 48109, United States

Henry Ford Hospital ( Site 0035)Recruiting

Detroit, Michigan 48202, United States

Cancer and Hematology Centers of Western Michigan ( Site 0015)Recruiting

Grand Rapids, Michigan 49503, United States

Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0078)Recruiting

Rochester, Minnesota 55905, United States

HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0032)Recruiting

Saint Louis Park, Minnesota 55426, United States

HealthPartners Cancer Center at Regions Hospital ( Site 0052)Recruiting

Saint Paul, Minnesota 55101, United States

St. Vincent Frontier Cancer Center-Research ( Site 0037)Recruiting

Billings, Montana 59102, United States

Oncology Hematology West, PC dba Nebraska Cancer Specialists - Grand Island ( Site 0076)Completed

Grand Island, Nebraska 68803, United States

Oncology Hematology West P.C. dba Nebraska Cancer Specialists ( Site 0026)Completed

Omaha, Nebraska 68130, United States

Comprehensive Cancer Centers of Nevada ( Site 0082)Recruiting

Las Vegas, Nevada 89148, United States

John Theurer Cancer Center at Hackensack University Medical Center ( Site 0016)Recruiting

Hackensack, New Jersey 07601, United States

University of New Mexico Comprehensive Cancer Center ( Site 0022)Recruiting

Albuquerque, New Mexico 87131, United States

Icahn School of Medicine at Mount Sinai ( Site 0009)Recruiting

New York, New York 10029, United States

Great Lakes Cancer Care ( Site 0047)Recruiting

Williamsville, New York 14221, United States

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0061)Recruiting

Columbus, Ohio 43221, United States

VA Portland Health Care System ( Site 0038)Recruiting

Portland, Oregon 97239, United States

Perelman Center for Advanced Medicine ( Site 0067)Recruiting

Philadelphia, Pennsylvania 19104, United States

Abramson Cancer Center - Penn Medicine ( Site 0079)Recruiting

Philadelphia, Pennsylvania 19106, United States

Memphis VA Medical Center ( Site 0072)Recruiting

Memphis, Tennessee 38105, United States

SCRI Oncology Partners ( Site 0074)Recruiting

Nashville, Tennessee 37203, United States

Henry-Joyce Cancer Clinic ( Site 0042)Recruiting

Nashville, Tennessee 37232, United States

UT Southwestern Medical Center ( Site 0039)Recruiting

Dallas, Texas 75390, United States

University of Texas-MD Anderson Cancer Center ( Site 0055)Recruiting

Houston, Texas 77030, United States

Blue Ridge Cancer Care ( Site 0024)Recruiting

Roanoke, Virginia 24014, United States

VA Puget Sound Health Care System ( Site 0054)Recruiting

Seattle, Washington 98108, United States

Fred Hutchinson Cancer Center ( Site 0060)Recruiting

Seattle, Washington 98109, United States

University Hospital and UW Health Clinics ( Site 0065)Recruiting

Madison, Wisconsin 53792, United States

Medical College of Wisconsin ( Site 0008)Recruiting

Milwaukee, Wisconsin 53226, United States

Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 0136)Recruiting

Berazategui, Buenos Aires B1884BBF, Argentina

Instituto de Investigaciones Clinicas Mar del Plata ( Site 0129)Recruiting

Mar del Plata, Buenos Aires B7600FZO, Argentina

Instituto Alexander Fleming ( Site 0125)Recruiting

Mar del Plata, Buenos Aires C1426ANZ, Argentina

Sanatorio Parque ( Site 0126)Recruiting

Rosario, Santa Fe Province S2000DSV, Argentina

Centro Medico Dra De Salvo ( Site 0132)Recruiting

CABA, C1426ABP, Argentina

Study CoordinatorContact

+5491151082017

Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0131)Recruiting

La Rioja, F5300COE, Argentina

Centro Oncologico de Integracion Regional. COIR ( Site 0130)Recruiting

Mendoza, M5500AYB, Argentina

Centro de Diagnostico Investigación y Tratamiento Oncológico (CeDIT) ( Site 0135)Recruiting

Salta, A4400AWG, Argentina

Instituto San Marcos ( Site 0137)Recruiting

San Juan, J5400EBB, Argentina

Blacktown Hospital ( Site 0154)Recruiting

Blacktown, New South Wales 2148, Australia

Macquarie University-MQ Health Clinical Trials Unit ( Site 0151)Completed

Macquarie University, New South Wales 2109, Australia

Gallipoli Medical Research Ltd ( Site 0153)Recruiting

Greenslopes, Queensland 4120, Australia

Peter MacCallum Cancer Centre ( Site 0152)Recruiting

Melbourne, Victoria 3000, Australia

Fiona Stanley Hospital ( Site 0155)Recruiting

Murdock, Western Australia 6150, Australia

Study CoordinatorContact

+61861525886

Ordensklinikum Linz GmbH Elisabethinen-Urologie ( Site 0170)Recruiting

Linz, Upper Austria 4020, Austria

Klinikum Wels-Grieskirchen GmbH ( Site 0171)Recruiting

Wels, Upper Austria 4600, Austria

Uniklinikum Salzburg Universitaetsklinik für Innere Medizin III ( Site 0172)Recruiting

Salzburg, 5020, Austria

Hospital Mario Penna ( Site 0179)Recruiting

Belo Horizonte, Minas Gerais 30380-472, Brazil

Hospital Universitário Evangélico Mackenzie ( Site 0181)Recruiting

Curitiba, Paraná 80730-150, Brazil

Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0184)Recruiting

Porto Alegre, Rio Grande do Sul 90020-090, Brazil

Hospital de Base de São José do Rio Preto ( Site 0176)Recruiting

São José do Rio Preto, São Paulo 15090-000, Brazil

IPITEC ( Site 0189)Recruiting

São Paulo, 01221-020, Brazil

IBCC - Núcleo de Pesquisa e Ensino ( Site 0183)Recruiting

São Paulo, 04014-012, Brazil

FALP ( Site 0201)Recruiting

Santiago, Region M. de Santiago 7500921, Chile

Bradfordhill ( Site 0200)Recruiting

Santiago, Region M. de Santiago 8420383, Chile

Peking University First Hospital ( Site 1434)Recruiting

Beijing, Beijing Municipality 100034, China

Shanghai General Hospital ( Site 1449)Recruiting

Beijing, Beijing Municipality 200080, China

The First Affiliated Hospital of Chonqing Medical University ( Site 1406)Recruiting

Chongqing, Chongqing Municipality 400016, China

Chongqing University Three Gorges Hospital ( Site 1405)Recruiting

Chongqing, Chongqing Municipality 404199, China

The First Affiliated Hospital Of Fujian Medical University ( Site 1452)Recruiting

Fuzhou, Fujian 350005, China

Guangzhou First People's Hospital ( Site 1410)Recruiting

Guangzhou, Guangdong 510000, China

Sun Yat-Sen University Cancer Center ( Site 1467)Recruiting

Guangzhou, Guangdong 510060, China

Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1402)Recruiting

Guangzhou, Guangdong 510220, China

Sun Yat-sen University Cancer Center ( Site 1409)Recruiting

Guangzhou, Guangdong 510300, China

The Fifth Affiliated Hospital of Sun Yat-Sen University ( Site 1459)Recruiting

Zhuhai, Guangdong 51900, China

Guangxi Medical University Cancer Hospital ( Site 1414)Recruiting

Nanning, Guangxi 530201, China

Henan Cancer Hospital ( Site 1472)Recruiting

Zhengzhou, Henan 450008, China

Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 1424)Recruiting

Wuhan, Hubei 430022, China

Hunan Cancer Hospital ( Site 1411)Recruiting

Changsha, Hunan 410013, China

Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School ( Site 1425)Recruiting

Nanjing, Jiangsu 210008, China

Jiangsu Province Hospital ( Site 1426)Recruiting

Nanjing, Jiangsu 210029, China

Zhongda Hospital Southeast University ( Site 1427)Recruiting

Nanjing, Jiangsu 214023, China

The Affiliated Hospital of Xuzhou Medical University ( Site 1438)Recruiting

Xuzhou, Jiangsu 221002, China

Jilin Province People's Hospital ( Site 1461)Recruiting

Changchun, Jilin 130021, China

The first affiliated Hospital of Xi an Jiaotong University ( Site 1408)Recruiting

Xi'an, Shaanxi 710061, China

Shandong Cancer Hospital ( Site 1421)Recruiting

Jinan, Shandong 250117, China

Shanghai Tenth People's Hospital ( Site 1441)Recruiting

Shanghai, Shanghai Municipality 200000, China

Fudan University Shanghai Cancer Center ( Site 1400)Recruiting

Shanghai, Shanghai Municipality 200032, China

Zhongshan Hospital Fudan University ( Site 1430)Recruiting

Shanghai, Shanghai Municipality 200032, China

Shanghai Tongji Hospital ( Site 1412)Recruiting

Shanghai, Shanghai Municipality 200065, China

Renji Hospital Shanghai Jiao Tong University School of Medicine ( Site 1457)Recruiting

Shanghai, Shanghai Municipality 200127, China

First Affiliated Hospital Of Shanxi Medical University ( Site 1460)Recruiting

Taiyuan, Shanxi 030001, China

West China Hospital of Sichuan University ( Site 1451)Recruiting

Chengdu, Sichuan 610041, China

West China Hospital, Sichuan University ( Site 1468)Recruiting

Chengdu, Sichuan 610041, China

The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 1469)Recruiting

Ürümqi, Xinjiang 830000, China

Zhejiang Cancer Hospital ( Site 1447)Recruiting

Hangzhou, Zhejiang 310022, China

The First Hospital of Jiaxing ( Site 1416)Recruiting

Jiaxing, Zhejiang 314001, China

The First Affiliated Hospital of Ningbo University ( Site 1419)Recruiting

Ningbo, Zhejiang 315010, China

The First Affiliated Hospital of Wenzhou Medical University ( Site 1437)Recruiting

Wenzhou, Zhejiang 325000, China

Promotora Medica Las Americas S.A ( Site 0234)Recruiting

Medellín, Antioquia 050025, Colombia

Centro Cancerológico del Caribe (CECAC) ( Site 0227)Recruiting

Barranquilla, Atlántico 080002, Colombia

Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 0229)Recruiting

Bogotá, Bogota D.C. 111321, Colombia

Instituto Nacional De Cancerologia ( Site 0237)Recruiting

Bogotá, Bogota D.C. 111511, Colombia

Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 0228)Recruiting

Valledupar, Cesar Department 200001, Colombia

FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0230)Recruiting

Bogota, Cundinamarca 110111, Colombia

Study CoordinatorContact

+57 3219198898

Oncologos Del Occidente ( Site 0231)Recruiting

Pereira, Risaralda Department 660001, Colombia

Fakultni nemocnice u sv. Anny v Brne ( Site 0264)Recruiting

Brno, Brno-mesto 602 00, Czechia

Masarykuv onkologicky ustav ( Site 0260)Recruiting

Brno, Brno-mesto 656 53, Czechia

Fakultni nemocnice Ostrava ( Site 0263)Recruiting

Ostrava - Poruba, Moravian-Silesian Region 708 52, Czechia

Study CoordinatorContact

+420597371111

Fakultni Nemocnice v Motole ( Site 0261)Recruiting

Prague, Praha 5 150 06, Czechia

Fakultni nemocnice Olomouc ( Site 0262)Recruiting

Olomouc, 779 00, Czechia

Herlev and Gentofte Hospital ( Site 0290)Recruiting

Herlev, Capital Region 2370, Denmark

Aalborg Universitetshospital, Syd ( Site 0293)Recruiting

Aalborg, North Denmark 9000, Denmark

Odense Universitetshospital ( Site 0294)Recruiting

Odense, Region Syddanmark 5000, Denmark

Vejle Sygehus ( Site 0291)Recruiting

Vejle, Region Syddanmark 7100, Denmark

Hôpital Foch ( Site 0309)Recruiting

Suresnes, Ain 92150, France

Hôpital Privé Clairval ( Site 0303)Recruiting

Marseille, Bouches-du-Rhone 13273, France

Centre François Baclesse ( Site 0311)Recruiting

Caen, Calvados 14076, France

CHU Besançon ( Site 0305)Completed

Besançon, Doubs 25000, France

Centre Hospitalier Universitaire de Nîmes - Institut de Canc-Medical Oncology ( Site 0313)Recruiting

Nîmes, Gard 30029, France

Clinique Francois Chenieux ( Site 0312)Recruiting

Limoges, Haute-Vienne 87039, France

Institut de Cancérologie de Lorraine Alexis Vautrin ( Site 0307)Recruiting

Vandœuvre-lès-Nancy, Meurthe-et-Moselle 54519, France

CHU de Rouen ( Site 0301)Recruiting

Rouen, Seine-Maritime 76031, France

Hôpital Saint-Louis ( Site 0310)Recruiting

Paris, Île-de-France Region 75010, France

Studienpraxis Urologie ( Site 0358)Recruiting

Nürtingen, Baden-Wurttemberg 72622, Germany

Klinikum Stuttgart - Katharinenhospital ( Site 0355)Recruiting

Stuttgart, Baden-Wurttemberg 70174, Germany

klinikum rechts der isar der technischen universität münchen ( Site 0350)Recruiting

Munich, Bavaria 81675, Germany

Klinikum Nuernberg Nord ( Site 0353)Recruiting

Nuremberg, Bavaria 90419, Germany

Universitätsklinikum Frankfurt Goethe-Universität ( Site 0354)Recruiting

Frankfurt am Main, Hesse 60590, Germany

Urologicum Duisburg ( Site 0361)Recruiting

Duisburg, North Rhine-Westphalia 47169, Germany

Universitaetsklinikum Schleswig Holstein ( Site 0360)Recruiting

Lübeck, Schleswig-Holstein 23538, Germany

Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0352)Recruiting

Berlin, 10117, Germany

Universitaetsklinik Hamburg-Eppendorf ( Site 0351)Recruiting

Hamburg, 20246, Germany

Henry Dunant Hospital ( Site 0385)Recruiting

Athens, Attica 115 26, Greece

Metropolitan General Hospital ( Site 0382)Recruiting

Athens, Attica 155 62, Greece

University General Hospital Attikon ( Site 0381)Recruiting

Chaidari Athens, Attica 124 62, Greece

Study CoordinatorContact

+302105831000

General Oncology Hospital of Kifisia "Agioi Anargyroi" ( Site 0384)Recruiting

Kifissia, Attica 145 64, Greece

Athens Medical Center ( Site 0383)Recruiting

Marousi, Attica 151 25, Greece

MEDI-K ( Site 0401)Recruiting

Guatemala City, 01009, Guatemala

Med Clinic ( Site 0403)Recruiting

Guatemala City, 01010, Guatemala

Onco Go ( Site 0402)Recruiting

Guatemala City, 01010, Guatemala

Queen Mary Hospital ( Site 0415)Recruiting

Hong Kong, Hong Kong

Tuen Mun Hospital ( Site 0416)Recruiting

New Territories, Hong Kong

St Vincent's University Hospital ( Site 0441)Recruiting

Dublin, Dublin D04 T6F4, Ireland

Cork University Hospital ( Site 0442)Recruiting

Cork, T12 E8YV, Ireland

Tallaght University Hospital ( Site 0440)Recruiting

Dublin, D24 NR0A, Ireland

Rambam Health Care Campus ( Site 0462)Recruiting

Haifa, 3109601, Israel

Shaare Zedek Medical Center ( Site 0468)Recruiting

Jerusalem, 9103102, Israel

Meir Medical Center ( Site 0464)Recruiting

Kfar Saba, 4428164, Israel

Rabin Medical Center ( Site 0461)Recruiting

Petah Tikva, 4941492, Israel

Sheba Medical Center ( Site 0460)Recruiting

Ramat Gan, 5265601, Israel

Sourasky Medical Center ( Site 0463)Recruiting

Tel Aviv, 6423906, Israel

Yitzhak Shamir Medical Center. ( Site 0466)Recruiting

Ẕerifin, 7033001, Israel

Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 0500)Recruiting

Milan, Lombardy 20133, Italy

Istituto Clinico Humanitas ( Site 0504)Recruiting

Rozzano, Milano 20089, Italy

Istituto Nazionale Tumori Regina Elena ( Site 0507)Recruiting

Rome, Roma 00128, Italy

Azienda Ospedaliero Universitaria Senese ( Site 0505)Recruiting

Siena, Tuscany 53100, Italy

Azienda USL 8 di Arezzo ( Site 0503)Recruiting

Arezzo, 52100, Italy

Humanitas Gavazzeni ( Site 0508)Completed

Bergamo, 24125, Italy

Azienda Ospedaliero Universitaria Policlinico Riuniti di Foggia ( Site 0510)Recruiting

Foggia, 71122, Italy

Azienda Ospedaliera Santa Maria Terni ( Site 0509)Recruiting

Terni, 05100, Italy

Centro Ricerche Cliniche di Verona ( Site 0506)Recruiting

Verona, 37134, Italy

Nagoya University Hospital ( Site 1508)Recruiting

Nagoya, Aichi-ken 466-8560, Japan

Toho University Sakura Medical Center ( Site 1503)Recruiting

Sakura, Chiba 285-8741, Japan

Ehime University Hospital ( Site 1514)Recruiting

Tōon, Ehime 791-0295, Japan

Hospital of the University of Occupational and Environmental Health, Japan ( Site 1510)Recruiting

Kitakyushu, Fukuoka 807-8556, Japan

Kurume University Hospital ( Site 1516)Recruiting

Kurume, Fukuoka 830-0011, Japan

Sapporo Medical University Hospital ( Site 1501)Recruiting

Sapporo, Hokkaido 060-8543, Japan

Hokkaido University Hospital ( Site 1500)Recruiting

Sapporo, Hokkaido 060-8648, Japan

Kobe University Hospital ( Site 1511)Recruiting

Kobe, Hyōgo 650-0017, Japan

Kanazawa Medical University Hospital ( Site 1507)Recruiting

Kahoku-gun, Ishikawa-ken 920-0293, Japan

Study CoordinatorContact

+81-76-286-3511

Shonan Kamakura General Hospital ( Site 1530)Recruiting

Kamakura, Kanagawa 247-8533, Japan

Oita University Hospital ( Site 1521)Recruiting

Yufu, Oita Prefecture 879-5593, Japan

University of the Ryukyus Hospital ( Site 1519)Recruiting

Ginowan, Okinawa 901-2725, Japan

Bell Land General Hospital ( Site 1509)Recruiting

Sakai, Osaka 599-8247, Japan

Dokkyo Medical University Saitama Medical Center ( Site 1502)Recruiting

Koshigaya, Saitama 343-8555, Japan

Hamamatsu University Hospital ( Site 1520)Recruiting

Hamamatsu, Shizuoka 431-3192, Japan

The Jikei University Hospital ( Site 1504)Recruiting

Minato, Tokyo 105-8471, Japan

Tokyo Women's Medical University ( Site 1505)Active, not recruiting

Shinjuku, Tokyo 162-8666, Japan

Yamaguchi University Hospital ( Site 1522)Recruiting

Ube, Yamaguchi 755-8505, Japan

University of Yamanashi Hospital ( Site 1506)Recruiting

Chūō, Yamanashi 409-3898, Japan

Harasanshin Hospital ( Site 1517)Recruiting

Fukuoka, 812-0033, Japan

Kyushu University Hospital ( Site 1515)Recruiting

Fukuoka, 812-8582, Japan

Gifu University Hospital ( Site 1527)Recruiting

Gifu, 501-1194, Japan

Hiroshima University Hospital ( Site 1512)Recruiting

Hiroshima, 734-8551, Japan

Kagoshima University Hospital ( Site 1518)Completed

Kagoshima, 890-8520, Japan

Kagoshima City Hospital ( Site 1528)Recruiting

Kagoshima, 890-8760, Japan

National Hospital Organization Kumamoto Medical Center ( Site 1524)Recruiting

Kumamoto, 860-0008, Japan

University Hospital,Kyoto Prefectural University of Medicine ( Site 1525)Recruiting

Kyoto, 602-8566, Japan

Nagano Municipal Hospital ( Site 1526)Recruiting

Nagano, 381-8551, Japan

Nagasaki University Hospital ( Site 1523)Recruiting

Nagasaki, 852-8501, Japan

Niigata Cancer Center Hospital ( Site 1529)Recruiting

Niigata, 951-8566, Japan

Tokushima University Hospital ( Site 1513)Recruiting

Tokushima, 770-8503, Japan

Sarawak General Hospital ( Site 0526)Recruiting

Kuching, Sarawak 93586, Malaysia

Sunway Medical Centre ( Site 0529)Recruiting

Petaling Jaya, Selangor 47500, Malaysia

Grupo Ollin Care ( Site 0544)Recruiting

Pachuca, Hidalgo 42000, Mexico

CIO - Centro de Inmuno-Oncología de Occidente ( Site 0541)Recruiting

Guadalajara, Jalisco 44630, Mexico

Higiea Oncologia ( Site 0542)Recruiting

Mexico City, Mexico City 11810, Mexico

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran ( Site 0545)Recruiting

Mexico City, Mexico City 14080, Mexico

Laboratorio de Patología Clínica del Hospital Universitario "Dr. José Eleuterio González" ( Site 0540)Recruiting

Monterrey, Nuevo León 64460, Mexico

Centro de Investigacion Clinica de Oaxaca ( Site 0543)Recruiting

Oaxaca City, Oaxaca 68020, Mexico

UMC St. Radboud ( Site 0601)Recruiting

Nijmegen, Gelderland 6525 GA, Netherlands

Maastricht UMC+ ( Site 0612)Recruiting

Maastricht, Limburg 6229 HX, Netherlands

VieCuri Medisch Centrum, locatie Venlo ( Site 0610)Recruiting

Venlo, Limburg 5912 BL, Netherlands

Nederlands Kanker Instituut - Antoni van Leeuwenhoek - NKI-AVL ( Site 0602)Recruiting

Amsterdam, North Holland 1066 CX, Netherlands

Tergooiziekenhuizen, locatie Hilversum ( Site 0619)Recruiting

Hilversum, North Holland 1212 VG, Netherlands

Spaarne Gasthuis - Hoofddorp ( Site 0608)Recruiting

Hoofddorp, North Holland 2134 TM, Netherlands

Ziekenhuisgroep Twente, locatie Almelo ( Site 0615)Recruiting

Hengelo, Overijssel 7555 DL, Netherlands

Erasmus Medisch Centrum ( Site 0611)Recruiting

Rotterdam, South Holland 3015 GD, Netherlands

Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 0600)Recruiting

Schiedam, South Holland 3118 JH, Netherlands

Haga Ziekenhuis locatie Leyweg ( Site 0607)Recruiting

The Hague, South Holland 2545 AA, Netherlands

Meander Medisch Centrum ( Site 0604)Recruiting

Amersfoort, Utrecht 3813 TZ, Netherlands

Martini Ziekenhuis ( Site 0621)Recruiting

Groningen, 9728 NT, Netherlands

St. Antonius Ziekenhuis, locatie Utrecht ( Site 0620)Recruiting

Utrecht, 3543 AZ, Netherlands

Akershus Universitetssykehus-Onkologisk avdeling ( Site 0650)Recruiting

Lorenskog, Akershus 1474, Norway

Study CoordinatorContact

004767960000

Sykehuset Innlandet HF Gjøvik ( Site 0652)Recruiting

Gjøvik, Oppland 2819, Norway

St. Olavs Hospital-Kreftklinikken ( Site 0651)Recruiting

Trondheim, Sor-Trondelag 7030, Norway

Oslo universitetssykehus, Radiumhospitalet ( Site 0653)Recruiting

Oslo, 0379, Norway

Unidad de Investigacion Oncologia Clínica Piura ( Site 0669)Recruiting

Castilla, Piura 20001, Peru

Hospital Cayetano Heredia ( Site 0667)Recruiting

Lima, 15012, Peru

IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0666)Recruiting

Lima, 15036, Peru

Instituto Nacional de Enfermedades Neoplásicas ( Site 0665)Recruiting

Lima, 15038, Peru

Instituto Neuro Cardiovascular de las Americas ( Site 0668)Recruiting

Lima, 15047, Peru

Clinical Research Center Spółka z ograniczoną odpowiedzialnością MEDIC-R Sp.k ( Site 0688)Completed

Poznan, Greater Poland Voivodeship 61-731, Poland

Centrum Onkologii im prof Franciszka Lukaszczyka ( Site 0696)Recruiting

Bydgoszcz, Kuyavian-Pomeranian Voivodeship 85-796, Poland

Pratia MCM Krakow ( Site 0692)Recruiting

Krakow, Lesser Poland Voivodeship 30-727, Poland

Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 0686)Recruiting

Siedlce, Masovian Voivodeship 08-110, Poland

Narodowy Instytut Onkologii im. Marii Skłodowskiej Curie ( Site 0685)Recruiting

Warsaw, Masovian Voivodeship 02-781, Poland

Pratia Onkologia Katowice ( Site 0693)Recruiting

Katowice, Silesian Voivodeship 40-519, Poland

National Cancer Centre Singapore ( Site 0760)Recruiting

Singapore, Central Singapore 168583, Singapore

Tan Tock Seng Hospital ( Site 0761)Recruiting

Singapore, Central Singapore 308433, Singapore

Cancercare Rondebosch Oncology ( Site 0771)Recruiting

Cape Town, Gauteng 7700, South Africa

Study CoordinatorContact

+27219443700

Wits Clinical Research ( Site 0776)Recruiting

Johannesburg, Gauteng 2193, South Africa

Wilgers Oncology Centre ( Site 0775)Recruiting

Pretoria, Gauteng 0081, South Africa

Curo Oncology Centre ( Site 0779)Recruiting

Pretoria, Gauteng 0084, South Africa

LIFE GROENKLOOF ( Site 0777)Recruiting

Pretoria, Gauteng 0181, South Africa

Chonnam National University Hwasun Hospital ( Site 0794)Recruiting

Hwasun Gun, Jeonranamdo 58128, South Korea

Study CoordinatorContact

82-61-379-7623

The Catholic University of Korea St. Mary s Hospital ( Site 0795)Recruiting

Seocho-gu, Seoul 06591, South Korea

Study CoordinatorContact

82-2-2258-6806

Asan Medical Center ( Site 0791)Recruiting

Songpagu, Seoul 05505, South Korea

Study CoordinatorContact

82-2-3010-6961

Ulsan University Hospital ( Site 0793)Recruiting

Donggu, Ulsan-Kwangyokshi 44033, South Korea

Severance Hospital Yonsei University Health System ( Site 0790)Recruiting

Seoul, 03722, South Korea

Samsung Medical Center ( Site 0792)Recruiting

Seoul, 06351, South Korea

Hospital Universitario Marqués de Valdecilla ( Site 0810)Recruiting

Santander, Cantabria 39008, Spain

CHUS - Hospital Clinico Universitario ( Site 0815)Recruiting

Santiago de Compostela, La Coruna 15706, Spain

HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA ( Site 0811)Recruiting

Majadahonda Madrid, Madrid 28220, Spain

Study CoordinatorContact

+34911917418

Hospital General Universitario Gregorio Marañón ( Site 0812)Recruiting

Madrid, Madrid, Comunidad de 28009, Spain

Hospital del Mar ( Site 0822)Recruiting

Barcelona, 08003, Spain

Hospital Vall D Hebron ( Site 0814)Recruiting

Barcelona, 08035, Spain

Hospital Universitario Reina Sofia ( Site 0816)Recruiting

Córdoba, 14004, Spain

Hospital Lucus Augusti ( Site 0813)Recruiting

Lugo, 27003, Spain

Hospital Universitario Quiron Madrid ( Site 0823)Recruiting

Madrid, 28223, Spain

Hospital Universitario Virgen de Valme ( Site 0819)Recruiting

Seville, 41014, Spain

Fundación Instituto Valenciano de Oncología ( Site 0821)Recruiting

Valencia, 46009, Spain

Skånes Universitetssjukhus Malmö ( Site 0841)Recruiting

Malmö, Skåne County 20502, Sweden

Södersjukhuset ( Site 0844)Recruiting

Stockholm, Stockholm County 11883, Sweden

Karolinska Universitetssjukhuset Solna ( Site 0843)Recruiting

Stockholm, Stockholm County 171 64, Sweden

Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 0840)Recruiting

Uppsala, Östergötland County 751 85, Sweden

Study CoordinatorContact

+46186110000

Kantonspital Aarau ( Site 0857)Recruiting

Aarau, Canton of Aargau 5001, Switzerland

University Hospital Basel ( Site 0859)Recruiting

Basel, Canton of Basel-City 4031, Switzerland

Hopitaux Universitaires de Geneve HUG. ( Site 0856)Recruiting

Geneva, Canton of Geneva 1211, Switzerland

HFR Fribourg - Hôpital Cantonal ( Site 0858)Recruiting

Fribourg, 1708, Switzerland

Stadtspital Zürich Triemli ( Site 0855)Recruiting

Zurich, 8063, Switzerland

National Taiwan University Hospital ( Site 0870)Recruiting

Taiwan, Taipei 10002, Taiwan

Study CoordinatorContact

+88623123456

Chang Gung Medical Foundation - Kaohsiung ( Site 0872)Recruiting

Kaohsiung City, 83301, Taiwan

Taichung Veterans General Hospital ( Site 0873)Recruiting

Taichung, 40705, Taiwan

Taipei Veterans General Hospital ( Site 0875)Recruiting

Taipei, 11217, Taiwan

Faculty of Medicine Siriraj Hospital ( Site 0885)Recruiting

Bangkoknoi, Bangkok 10700, Thailand

Study CoordinatorContact

+6624194488

Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 0887)Recruiting

Dusit, Bangkok 10300, Thailand

Sakarya Egitim ve Arastırma Hastanesi ( Site 0897)Recruiting

Adapazarı, Sakarya 54290, Turkey (Türkiye)

Adana Medical Park Seyhan Hastanesi ( Site 0906)Recruiting

Adana, 01140, Turkey (Türkiye)

Hacettepe Universitesi Tip Fakultesi ( Site 0895)Recruiting

Ankara, 06230, Turkey (Türkiye)

Gazi University Health Research and Application Center Gazi Hospital ( Site 0903)Recruiting

Ankara, 06560, Turkey (Türkiye)

Ankara Universitesi Tıp Fakultesi Hastanesi ( Site 0901)Recruiting

Ankara, 06590, Turkey (Türkiye)

Istanbul Universitesi Cerrahpasa ( Site 0896)Recruiting

Istanbul, 34098, Turkey (Türkiye)

Konya Necmettin Erbakan Universitesi ( Site 0905)Recruiting

Konya, 42080, Turkey (Türkiye)

Addenbrooke's Hospital ( Site 0915)Recruiting

Cambridge, Cambridgeshire CB2 2QQ, United Kingdom

University College London Hospital ( Site 0920)Recruiting

London, Camden NW1 2PG, United Kingdom

Royal Devon & Exeter Hospital ( Site 0924)Recruiting

Exeter, Devon EX2 5DW, United Kingdom

Queen Elizabeth Hospital Birmingham ( Site 0923)Recruiting

Birmingham, England B15 2TH, United Kingdom

Mount Vernon Hospital ( Site 0921)Recruiting

Northwood, Hillingdon HA6 2RN, United Kingdom

St Bartholomew s Hospital ( Site 0925)Recruiting

London, London, City of EC1A 7BE, United Kingdom

Royal Marsden Hospital (Sutton) ( Site 0922)Recruiting

Sutton, London, City of SM2 5PT, United Kingdom

Torbay Hospital ( Site 0918)Recruiting

Devon, United Kingdom TQ2 7AA, United Kingdom

Study CoordinatorContact

+441803656615