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| ID | Type | Description | Link |
|---|---|---|---|
| 1U01NR021591 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Nursing Research (NINR) | NIH |
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This project will compare the health effects of public housing renovation, neighborhood built and social environment improvements, and indoor air purification, alone and in combination, as well as the cost effectiveness of each approach.
STUDY 1: The study will assess the effects of public housing and neighborhood environment (built and social) improvements on health-related behaviors, psychosocial and physiologic stress, and self-reported and physiological markers of lung health and chronic disease.
STUDY 2: The study will determine whether indoor air purification can positively impact lung health in public housing sites not undergoing housing renovation, comparing a site near industrial pollution vs one less contaminated.
Participants will complete surveys, physical exam, lung function tests, and blood draw. An indoor air purifier with a usage tracker and an indoor air quality monitor will be provided, and used filters will be analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elyton Village Community | Active Comparator | Participants will receive improved neighborhood environment (built and social) and indoor air purification. |
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| Southtown Court Community | Active Comparator | Participants will receive new public housing. |
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| Smithfield Court Community | Active Comparator | Participants will receive new public housing and improved neighborhood environment (built and social). |
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| Collegeville Community | Active Comparator | Participants will receive indoor air purification. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Indoor Air Purification | Other | An indoor air purifier with a dual HEPA/activated carbon filter, a usage tracker, and an indoor air quality monitor will be installed in public housing residences. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Patient-Reported Outcomes Measurement Information System (PROMIS-10) Global Health | A self-reported measure of physical, mental, and social health. 10 item questionnaire T-score metric from zero to 100 where higher T-scores indicate better health. | Baseline, 12 months, 24 months |
| Change in Allostatic load | Measure of cumulative stress burden as the number of 10 indicators above a threshold: (1) serum albumin <3.8 g/dL, (2) C Reactive Protein (CRP) >3 mg/L, (3) High-Density Lipoprotein (HDL) <40 mg/dL, (4) total cholesterol ≥240 mg/dL, (5) heart rate ≥90 beats/min, (6) systolic Blood Pressure (BP) ≥140 mmHg, (7) diastolic BP ≥90 mmHg, (8) serum creatinine ≥1.3 mg/dL, (9) Blood Urea Nitrogen (BUN) ≥18 mg/dL, and (10) waist circumference >88 cm in women, >102 cm in men. | Baseline, 12 months |
| Change in Indoor Air Quality | Particulate matter (PM2.5). Measures particles in the air that are 2.5 micrometers or smaller in diameter. | Baseline, 6 months, 12 months (Study 2 only) |
| Measure | Description | Time Frame |
|---|---|---|
| The percentage change in FEV1/FVC | FEV1/FVC. A measure of lung funtion that compares the amount of air exhaled in the first second (FEV1) to the total amount of air exhaled in a forced breath (FVC). | Baseline, 6 months, 12 months (Study 2 only) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Gabriela R Oates, PhD | Contact | 205-996-5689 | goates@uab.edu | |
| Joy R Ledvina, Program Director, MBA | Contact | 205-975-7852 | jrledvina@uabmc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Gabriela R Oates, PhD | University of Alabama at Birmingham (UAB) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UAB Lung Health Center | Recruiting | Birmingham | Alabama | 35233 | United States |
Individual participant data that underlie the reported results, after de-identification.
Data will be available beginning 12 months and ending 36 months after publication.
Data will be available to investigators who submit an approved proposal and sign a Data Use Agreement. Proposals should be submitted to goates@uab.edu.
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| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D002908 | Chronic Disease |
| ID | Term |
|---|---|
| D012140 | Respiratory Tract Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Neighborhood Improvements | Other | Improved built environment (green space, sidewalks, street lights) and social environment (educational and workforce development programs, wrap-around social services, Internet access). |
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| Housing Improvements | Other | High-quality public housing |
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