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This study aims to investigate, based on existing knowledge, the incidence of occult thyroid carcinoma in a cohort of patients with MNG, providing new insights into the prevalence and characteristics of thyroid malignancies in MNG. It seeks to contribute to optimizing diagnostic evaluations for patients with multinodular goiter.
This retrospective study included patients with a preoperative diagnosis of multinodular goiter who underwent total or partial thyroidectomy from January 2018 to May 2024 at the Department of Medical and Surgical Sciences at the University Hospital "Ospedali Riuniti" in Foggia. The study's objective was to investigate the incidence of thyroid carcinoma in patients undergoing thyroidectomy for MNG, also analyzing associated demographic and clinical variables.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient with multinodular goiter who underwent total or partial thyroidectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| total or partial thyroidectomy | Procedure | Total thyroidectomy is a surgical procedure that involves the complete removal of the thyroid gland. It is performed to treat conditions such as thyroid cancer, large goiters, or severe hyperthyroidism. The surgery is typically conducted under general anesthesia through an incision in the lower neck. Postoperative management may include hormone replacement therapy with levothyroxine to compensate for the loss of thyroid function. Potential complications include hypocalcemia due to parathyroid gland injury and vocal cord dysfunction from recurrent laryngeal nerve damage. |
| Measure | Description | Time Frame |
|---|---|---|
| incidence of occult thyroid carcinoma | Incidence of occult thyroid carcinoma in a cohort of patients with multinodular goiter, providing new insights into the prevalence and characteristics of thyroid malignancies. | 6 years |
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Inclusion Criteria:
Exclusion Criteria:
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Patients of both sex with cancer incidence in multinodular thyroid goiter who underwent surgery in the same center
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Foggia | Foggia | FG | 71122 | Italy |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Apr 4, 2025 | Apr 4, 2025 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D006044 | Goiter, Nodular |
| D013964 | Thyroid Neoplasms |
| ID | Term |
|---|---|
| D006042 | Goiter |
| D013959 | Thyroid Diseases |
| D004700 | Endocrine System Diseases |
| D004701 | Endocrine Gland Neoplasms |
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|
| D009371 |
| Neoplasms by Site |
| D009369 | Neoplasms |
| D006258 | Head and Neck Neoplasms |