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| Name | Class |
|---|---|
| Almirall, S.A. | INDUSTRY |
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Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological conditions. Alloknesia occurs mainly in the context of chronic pruritus. Consequently, patients suffering from chronic pruritus frequently perceive light touch sensations as pruritic, which can be particularly unpleasant and alter human interactions and quality of life on a daily basis. However, the epidemiology and burden of alloknesia have never been studied, whatever the cause of chronic pruritus.Atopic dermatitis is one of the main diseases causing chronic itching, and patients frequently complain of alloknesia. In this study, the investigators are studying the frequency of alloknesia in patients with atopic dermatitis and measuring the consequences of alloknesia in these patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with atopic dermatitis | Patients will take part in the study on a single occasion, during which they will complete the various questionnaires (Alloknesia diagnostic questionnaire, WI-NRS scale, ItchyQol questionnaire, DLQI questionnaire, HADS questionnaire, PUSH-D questionnaire, PSS (Perceived Stress Scale), Epworth questionnaire, ISS questionnaire). There will be no follow-up. |
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| Measure | Description | Time Frame |
|---|---|---|
| Alloknesia diagnostic questionnaire | The questionnaire consists of a single question: 'Can the touch of your skin by clothing, air movements or the light touch of an object or another person trigger itching? | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| Measure | Description | Time Frame |
|---|---|---|
| WI-NRS scale / Worst Itch Numeric Rating Scale | Digital pruritus scale, measuring the worst daily itching intensity 0 to 10. 0: no itching 10: worst itch imaginable | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with atopic dermatitis
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Laurent MISERY, PUPH | Contact | 02 98 22 33 15 | laurent.misery@chu-brest.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU d'Angers | Recruiting | Angers | 49100 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 1798888 | Background | Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991 Dec;14(6):540-5. doi: 10.1093/sleep/14.6.540. | |
| 8033378 | Background | Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994 May;19(3):210-6. doi: 10.1111/j.1365-2230.1994.tb01167.x. |
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All collected data that underlie results in a publication
Data will be available after the publication of result and ending fifteen years following the last visit of the last patient
Data access requests will be reviewed by the internal committee of Brest UH. Requestors will be required to sign and complete a data access agreement.
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| ItchyQoL questionnaire / quality-of life instrument for pruritus |
Quality-of life instrument for pruritus Itch-related quality of life 0 to 110 |
| At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| DLQI questionnaire / Dermatology Life Quality Index | Skin-related quality of life 0 to 30 | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| HADS questionnaire / Hospital Anxiety and Depression Scale | The HAD scale is an instrument for screening for anxiety and depressive disorders. 0 to 21 | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| PUSH-D questionnaire / Patient Unique Stigmatization Holistic tool in dermatology | PUSH-D allows a comprehensive view of the degree of stigmatization in visible skin disorders. 0 to 68 | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| Stress perçu : PSS / Perceived Stress Scale | The PSS (Perceived Stress Scale) is a scale for measuring perceived stress. 0 to 40 | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| Epworth questionnaire / sleepiness scale | The Epworth Test is a self-administered questionnaire that assesses subjective sleepiness and fatigue. 0 to 21 | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| ISS questionnaire / Sexual Satisfaction Index | Satisfaction with sexual relations 25 to 175 | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. |
| CHU de Brest | Recruiting | Brest | 29200 | France |
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| CHD Vendée | Recruiting | La Roche-sur-Yon | 85925 | France |
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| Groupe Hospitalier Bretagne Sud | Recruiting | Lorient | 56100 | France |
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| CHU de Nantes Hôtel-Dieu | Recruiting | Nantes | 44093 | France |
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| CHU de Rennes | Recruiting | Rennes | 35000 | France |
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| CHU de Tours | Recruiting | Tours | 37170 | France |
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| CH Bretagne Atlantique | Recruiting | Vannes | 56000 | France |
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| 32936233 | Background | Kimel M, Zeidler C, Kwon P, Revicki D, Stander S. Validation of Psychometric Properties of the Itch Numeric Rating Scale for Pruritus Associated With Prurigo Nodularis: A Secondary Analysis of a Randomized Clinical Trial. JAMA Dermatol. 2020 Dec 1;156(12):1354-1358. doi: 10.1001/jamadermatol.2020.3071. |