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This study compares the efficacy of two drugs, namely flucanazole and itraconazole for the treatment of a common fungal infection of skin.
Pityriasis versicolor is a common fungal infection of the superficial skin layers. Avalible treatment options include topical and systemic drugs. fluconazole and itraconazole are commonly used systemic agents. The aim of this study is to compare the efficacy of the two systemic drugs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A, Fluconazole group | Experimental | Group A consists of patients in whom oral fluconazole is given in dose of 300mg once weekly for 2 weeks. |
|
| Group B, Itraconazole group | Experimental | Group B consists of patients in whom oral Itraconazole is given in dose of 100mg Twice for 5 days. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fluconazole | Drug | Oral fluconazole prescribed to group A |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Efficacy of Treatment | Efficacy of treatment is defined by absence of scaling by naked eye examination ,absence of yellow or golden scale reflection on woods lamp examination and absence of fungal hyphae on microscopic examination. | Upto 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Khyber Teaching Hospital | Recruiting | Peshawar | KPK | 25000 | Pakistan |
Patient's confidentiality may be breached.
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| ID | Term |
|---|---|
| D014010 | Tinea Versicolor |
| ID | Term |
|---|---|
| D003881 | Dermatomycoses |
| D009181 | Mycoses |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D015725 | Fluconazole |
| D017964 | Itraconazole |
| ID | Term |
|---|---|
| D014230 | Triazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| Itraconazole |
| Drug |
Oral itraconazole prescribed to Group B |
|
| D012874 |
| Skin Diseases, Infectious |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D010879 |
| Piperazines |