AI Chatbot for Migraine Management in Hong Kong Women

Development and Evaluation of an AI-empowered Voice-interactive Chatbot for Migraine Management Among Hong Kong Women: a Randomized Crossover Trial

The goal of this randomized crossover trial is to examine whether the AI-empowered chatbot will effectively collect comprehensive migraine feature data and demonstrate higher compliance, accuracy, utilization, acceptability, feasibility, and validity in migraine feature tracking compared to traditional paper-based migraine diaries among Hong Kong women with migraine.

Participants will use different tools (AI-empowered voice-interactive chatbot or paper migraine diary) for migraine tracking. Participants will be randomly allocated to one of two intervention sequences: (1) AI-empowered voice-interactive chatbot followed by paper migraine diary, or (2) paper migraine diary followed by AI-empowered voice-interactive chatbot. The study will consist of two intervention periods, each lasting one month, with a 1:1 allocation ratio.

Inclusion Criteria:

• Women aged 18 years or older
• Meet diagnostic criteria for migraine according to ICHD-3
• Experiencing at least 2 headache days per month
• Living in Hong Kong
• Fluent in Cantonese
• Owning a smartphone with internet access
• Willing to provide informed consent

Exclusion Criteria:

• Individuals with severe cognitive impairments or communication difficulties
• Those unable to use a smartphone or the chatbot due to physical or mental limitations
• Using another alternative electronic migraine diary during recruitment or in the past 12 weeks