This study used the "Safe and Protected Sex" intervention, adapted and validated from an HIV prevention program to focus on HPV. The intervention consists of a single module with two stages aimed at increasing HPV knowledge by enhancing personal (self-determination) and social (controlled behavior) motivation.

Module 1: "Nursing Consultation on HPV" This structured, planned process follows Corona and Kaltmeier's (2012) horizontal methodology, promoting self-care through social support and trust in nurse-patient dialogue. The goal is to provide counseling on HPV prevention and responsible sexual behavior while acknowledging participants' prior knowledge.

Stage 1: 4.21-minute educational video, "HPV Fun Facts," uses persuasive narrative to explain HPV transmission, symptoms, complications, and prevention.

Stage 2: 45-minute "Friendly Educational Guidance" session uses open-ended questions to explore participants' experiences, clarify misconceptions, and reinforce key information

For the QA, the baseline measurement (test) was performed once the participant arrived at the sexual health clinic of the School of Nursing with the use of an electronic device that contained the first link of the QuestionPro® platform; subsequently, the participant was given information related to HPV through the usual methodology (diptych) (See Appendix H) that the health system in Mexico carries out. Finally, the second measurement was performed after reading the diptych with the use of the electronic device and the second link of the QuestionPro® platform, prior to the application of the intervention.

This study used the "Safe and Protected Sex" intervention (Báez et al., 2019), adapted and validated from an HIV prevention program to focus on HPV. The intervention consists of a single module with two stages aimed at increasing HPV knowledge by enhancing personal (self-determination) and social (controlled behavior) motivation.

Module 1: "Nursing Consultation on HPV" This structured, planned process follows Corona and Kaltmeier's (2012) horizontal methodology, promoting self-care through social support and trust in nurse-patient dialogue. The goal is to provide counseling on HPV prevention and responsible sexual behavior while acknowledging participants' prior knowledge.

Stage 1: A 4.21-minute educational video, "HPV Fun Facts," uses persuasive narrative to explain HPV transmission, symptoms, complications, and prevention.

Stage 2: A 45-minute "Friendly Educational Guidance" session uses open-ended questions to explore participants' experiences.

This Spanish-language questionnaire is intended to measure knowledge about HPV. It is structured by 38 questions, distributed in four dimensions: 1) causal agent of HPV (1, 2 and 3); 2) risk factors (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14 and 15); 3) signs and symptoms (16, 17, 18, 19 and 20) and 4) prevention, diagnosis and treatment (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37 and 38).

The structure for answering each of the questions is through a Likert-type scale, where three possible options are presented: A= true, B= false and C= don't know. To obtain the cut-off points of the instrument, percentiles (zero to 100) will be used, where Percentile 1 (P125) = no knowledge, Percentile 2 (P250) = insufficient knowledge, Percentile 3 (P375) = fair knowledge and Percentile 4 (P4100) = adequate knowledge

To measure personal motivation (self-determination), the Personal Motivation Questionnaire adapted to the Mexican context. It consists of 13 items, which address the preventive behaviors performed by the homosexual male as a result of an emotional-cognitive process, derived from the values and beliefs related to knowledge of HPV, which are manifested during the nursing consultation, through the intervention "Safe and Protected Sex". The response form is Likert type: 1= Strongly agree, 2=Significantly agree, 3= Agree, 4= Neither agree nor disagree, 5= Disagree, 6= Strongly disagree, 7= Strongly disagree, also the score ranges from 13 to 91 points, however for a better interpretation of the data the values are converted into a scale from 0 to 100, where high scores indicate a higher personal motivation during the nursing consultation.

The validity of the instrument was through eight experts, which yielded a content validity index