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The goal of this observational study is to learn about the effects of psychiatric drug therapies on intra- and extra-oral sicca symptoms and salivation. The main question that it aims to answer is:
Does taking psychiatric medication cause oral dryness and/or any changes on whole and minor saliva secretion? Participants taking psychiatric medication answered a 16-question questionnare, and their saliva production was measured by Periotron device and by spitting method.
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| Measure | Description | Time Frame |
|---|---|---|
| Unstimulated whole saliva flow rate (UWS) | UWS was determined using the "spitting" method (Sreebny 2000). Whole saliva was collected for 5 minutes into a previously weighted empty cup, and then measured again after collecting the saliva. The results are in ml/min. | through study completion, an average of 1 year |
| Minor salivary gland (MSG) secretions | Palatal and labial MSG flow rates were measured by the Periotron 8010® (Oraflow Inc. Amytiville, USA) device with filter paper discs. The results are transferred into µl/cm2/min. | Through study completion, an average of 1 year |
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Inclusion Criteria:
In the psychiatric group, the inclusion criteria was taking specific psychiatric medications.
Exclusion Criteria:
In the control group the exclusion criteria was reporting any diseases and taking medicines.
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Outpatient Clinic, Department of Psychiatry and Psychotherapy and Dental Teaching Center, Semmelweis University, Budapest, Hungary
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41764456 | Derived | Kovacs A, Karolyhazy K, Tolna J, Gotai L, Demeter T, Keremi B, Vag J, Marton K. Effects of frequently used psychiatric drugs on subjective dry mouth, salivary secretion and DMFT in outpatients. BMC Oral Health. 2026 Feb 28;26(1):594. doi: 10.1186/s12903-026-07958-8. |
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| ID | Term |
|---|---|
| D001523 | Mental Disorders |
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