Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| University of Nevada, Las Vegas | OTHER |
| Hacettepe University | OTHER |
Not provided
Not provided
Not provided
The aim of this study is to determine the efficacy of Mosquito Shield (spatial repellent) in reducing cutaneous leishmaniasis case incidence among internally displaced persons and sandfly density in temporary shelters and camp settings in Ar-Raqqa governorate, North-East Syria.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | 2 clusters received: 1.The study intervention was Mosquito ShieldTM. The active ingredient releases on a controlled basis over a 1-month period (1 emanator in rooms up to 18 m 2 / 2 emanator per 9 m). The households in the intervention arm were provided with Mosquito ShieldTM for 9 months (April-December 2021). This was distributed directly to households every month with pictogram instructions in the local language describing the correct intervention usage: how to open Mosquito ShieldTM, the number to be installed per room, how to attach and position Mosquito ShieldTM and the duration of Mosquito ShieldTM usage (30 days) prior to replacement. 2. IECs (brochures and posters) with information on cutaneous leishmaniasis transmission, prevention, clinical symptoms, correct treatment seeking practices and treatment locations. 3. Free of charge access to diagnostic and treatment services |
|
| Control | No Intervention | 4 clusters received: 1. IECs (brochures and posters) with information on cutaneous leishmaniasis transmission, prevention, clinical symptoms, correct treatment seeking practices and treatment locations. 2. Free of charge access to diagnostic and treatment services |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Spatial repellant emanator | Device | Spatial emanator with an active ingredient Transfluthrin (C15H12Cl2F4O2, 110mg, EPA registered number 432-1588). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Epidemiological outcome: cutaneous leishmaniasis incidence | Cutaneous leishmaniasis incidence per 1,000 will be estimated as the total number of cutaneous leishmaniasis episodes per 1,000 persons over the course of the trial. Two different incubation times or diagnostic cut-offs will be used: at 2 months post-intervention (from August 2021 to April 2022) and at 4 months post-intervention (from August 2021 to April 2022). | 11 or 9 months |
| Entomological outcome: phlebotomine sandfly density | Phlebotomine sandfly density will be estimated monthly using Centers for Disease Control and Prevention light traps inside shelters. | 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Intervention feasibility, acceptability and uptake | To measure community and household intervention acceptability and uptake, a questionnaire will be conducted post-intervention. | 11 months |
Not provided
Inclusion Criteria:
Known history of cutaneous leishmaniasis in camp Sleeping under same shelter type (all UNHCR tents / plastic sheets) Camp easily accessible by road Camps a minimum of 5km apart Adequate security levels
Exclusion Criteria:
Camps closer than 5km from a camp included in the study Camps with no previously recorded cases of cutaneous leishmaniasis Displaced communities living outside of defined camp settings
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Richard J Allan, PhD | The Mentor Initiative | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The MENTOR Initiative, North East Syria | Ar-Raqqa | Syria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40611204 | Derived | Allan R, Scherrer R, Kasap OE, Paris L, Scott T, Sauskojus H, Wetherill O, Estecha-Querol S, Alkhalaf Z, Karakus M, Yilmaz A, Alten B, Messenger LA. Enhancing protection against vector-borne diseases in forcibly displaced communities: evaluating the efficacy of spatial repellents for cutaneous leishmaniasis control in North-East Syria. BMC Med. 2025 Jul 3;23(1):401. doi: 10.1186/s12916-025-04244-2. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Neither the deliverers of the intervention nor the outcome assessors are blinded to the group allocations
Not provided
| ID | Term |
|---|---|
| D016773 | Leishmaniasis, Cutaneous |
| D000079426 | Vector Borne Diseases |
| ID | Term |
|---|---|
| D007896 | Leishmaniasis |
| D056986 | Euglenozoa Infections |
| D011528 | Protozoan Infections |
| D010272 | Parasitic Diseases |
| D007239 | Infections |
| D012876 | Skin Diseases, Parasitic |
| D012874 | Skin Diseases, Infectious |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
Not provided
Not provided