The aim of this study is to take stock of the situation of adult patients with severe asthma on biotherapy, followed up at Poitiers University Hospital, and in particular to increase our knowledge of factors predictive of response to biotherapy. The main aim is to improve the management of adult severe asthma patients treated with biotherapy, according to their allergic status.

Inclusion Criteria:

• Severe asthma patient on biotherapy
• Age > or = 18 years
• Follow-up at Poitiers University Hospital

Exclusion Criteria:

• Absence of allergological assessment
• Patient's refusal to participate in study

severe asthma patients on dual therapy at POITIERS University Hospital