The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 3)

The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations: A Novel Intervention for Children at Risk for Aspiration-Associated Complications (Aim 3)

Using a longitudinal cohort design, we will compare the impact of a high BA-binding blenderized diet compared to a low BA-binding blenderized diet and an amino acid-based formula, on gastrointestinal and pulmonary hospitalization and emergency room visit rates over six months.

Inclusion Criteria:

• receive at least 80% of their nutritional needs via gastrostomy
• receive an International Dysphagia Diet Standardization Initiative level 4 commercial blend, home blend or amino acid-based formula
• receive their bolus feeds within 30 minutes or less.

Exclusion Criteria:

• have undergone anti-reflux surger
• receive post-pyloric feeds
• receive regular daily prophylactic antibiotics.